Biomarkers of coronary artery disease: the promise of the transcriptome

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Biomarkers of coronary artery disease: the promise of the transcriptome. / Siemelink, Marten Antoon; Zeller, Tanja.

In: CURR CARDIOL REP, Vol. 16, No. 8, 08.2014, p. 513.

Research output: SCORING: Contribution to journalSCORING: Review articleResearch

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@article{45cc1e4184f04d818b9e00f0c66b62e4,
title = "Biomarkers of coronary artery disease: the promise of the transcriptome",
abstract = "The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification. ",
keywords = "Biomarkers/analysis, Coronary Artery Disease/diagnosis, Gene Expression Profiling/methods, Genomics/methods, Humans, Transcriptome",
author = "Siemelink, {Marten Antoon} and Tanja Zeller",
year = "2014",
month = aug,
doi = "10.1007/s11886-014-0513-4",
language = "English",
volume = "16",
pages = "513",
journal = "CURR CARDIOL REP",
issn = "1523-3782",
publisher = "Current Medicine Group",
number = "8",

}

RIS

TY - JOUR

T1 - Biomarkers of coronary artery disease: the promise of the transcriptome

AU - Siemelink, Marten Antoon

AU - Zeller, Tanja

PY - 2014/8

Y1 - 2014/8

N2 - The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification.

AB - The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification.

KW - Biomarkers/analysis

KW - Coronary Artery Disease/diagnosis

KW - Gene Expression Profiling/methods

KW - Genomics/methods

KW - Humans

KW - Transcriptome

U2 - 10.1007/s11886-014-0513-4

DO - 10.1007/s11886-014-0513-4

M3 - SCORING: Review article

C2 - 24950674

VL - 16

SP - 513

JO - CURR CARDIOL REP

JF - CURR CARDIOL REP

SN - 1523-3782

IS - 8

ER -