Biological isoeffect distributions: consideration of the influence of dose per fraction and overall treatment time. A possible tool in future treatment planning.
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Biological isoeffect distributions: consideration of the influence of dose per fraction and overall treatment time. A possible tool in future treatment planning. / Beck-Bornholdt, Hans-Peter; Schmidt, R; Schwarz, R C; Hübener, K H.
In: STRAHLENTHER ONKOL, Vol. 167, No. 12, 12, 1991, p. 708-715.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Biological isoeffect distributions: consideration of the influence of dose per fraction and overall treatment time. A possible tool in future treatment planning.
AU - Beck-Bornholdt, Hans-Peter
AU - Schmidt, R
AU - Schwarz, R C
AU - Hübener, K H
PY - 1991
Y1 - 1991
N2 - The biological isoeffect distributions are calculated on the basis of the physical isodose distributions. They consider parameters of biological relevance such as the dose per fraction and the overall treatment time. A clinical example is presented to illustrate the method. The technique presented in this paper only requires minimal modifications in the conventional computer programs for treatment planning and can be updated very easily. The calculation of biological isoeffect distributions is a simple technique to facilitate the transfer of new radiobiological and clinical findings on alpha/beta ratios, tolerance doses and repopulation kinetics, into treatment planning. However, before they can be introduced into clinical practice, more reliable radiobiological data on normal tissues and tumours are required.
AB - The biological isoeffect distributions are calculated on the basis of the physical isodose distributions. They consider parameters of biological relevance such as the dose per fraction and the overall treatment time. A clinical example is presented to illustrate the method. The technique presented in this paper only requires minimal modifications in the conventional computer programs for treatment planning and can be updated very easily. The calculation of biological isoeffect distributions is a simple technique to facilitate the transfer of new radiobiological and clinical findings on alpha/beta ratios, tolerance doses and repopulation kinetics, into treatment planning. However, before they can be introduced into clinical practice, more reliable radiobiological data on normal tissues and tumours are required.
M3 - SCORING: Zeitschriftenaufsatz
VL - 167
SP - 708
EP - 715
JO - STRAHLENTHER ONKOL
JF - STRAHLENTHER ONKOL
SN - 0179-7158
IS - 12
M1 - 12
ER -
