Beta dosimetry with microMOSFETs for endovascular brachytherapy
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Beta dosimetry with microMOSFETs for endovascular brachytherapy. / Drud, Eva; Todorovic, Manuel; Schönborn, Thies; Schmidt, Rainer.
In: PHYS MED BIOL, Vol. 51, No. 23, 07.12.2006, p. 5977-86.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Beta dosimetry with microMOSFETs for endovascular brachytherapy
AU - Drud, Eva
AU - Todorovic, Manuel
AU - Schönborn, Thies
AU - Schmidt, Rainer
PY - 2006/12/7
Y1 - 2006/12/7
N2 - The aim of this study was to investigate if microMOSFETs are suitable for the dosimetry and quality assurance of beta sources. The microMOSFET dosimeters have been tested for their angular dependence in a 6 MeV electron beam. The dose rate dependence was measured with an iridium-192 afterloading source. By varying the source-to-surface distance (SSD) in a 12 MeV electron beam the dose rate dependence in an electron beam was also investigated. To measure a depth dose curve the dose rate at 2, 5, 8 and 12 mm distance from the beta source train axis was determined with the OPTIDOS and the microMOSFET detector. A comparison between the two detector types shows that the microMOSFET is suitable for quality assurance of beta sources for endovascular brachytherapy (EVBT). The homogeneity of the source is checked by measurements at five points (for the 60 mm source at 10, 20, 30, 40 and 50 mm) along the source train. The microMOSFET was then used to evaluate the influence of a common stent type (single layer stainless steel) on the dose distribution in water. The stent led to a dose inhomogeneity of +/-8.5%. Additionally the percentage depth dose curves with and without a stent were compared. The depth dose curves show good agreement which means that the stent does not change the beta spectrum significantly.
AB - The aim of this study was to investigate if microMOSFETs are suitable for the dosimetry and quality assurance of beta sources. The microMOSFET dosimeters have been tested for their angular dependence in a 6 MeV electron beam. The dose rate dependence was measured with an iridium-192 afterloading source. By varying the source-to-surface distance (SSD) in a 12 MeV electron beam the dose rate dependence in an electron beam was also investigated. To measure a depth dose curve the dose rate at 2, 5, 8 and 12 mm distance from the beta source train axis was determined with the OPTIDOS and the microMOSFET detector. A comparison between the two detector types shows that the microMOSFET is suitable for quality assurance of beta sources for endovascular brachytherapy (EVBT). The homogeneity of the source is checked by measurements at five points (for the 60 mm source at 10, 20, 30, 40 and 50 mm) along the source train. The microMOSFET was then used to evaluate the influence of a common stent type (single layer stainless steel) on the dose distribution in water. The stent led to a dose inhomogeneity of +/-8.5%. Additionally the percentage depth dose curves with and without a stent were compared. The depth dose curves show good agreement which means that the stent does not change the beta spectrum significantly.
KW - Biophysical Phenomena
KW - Biophysics
KW - Brachytherapy/methods
KW - Gamma Rays/therapeutic use
KW - Humans
KW - Quality Assurance, Health Care
KW - Radiometry/instrumentation
KW - Radiotherapy Planning, Computer-Assisted
KW - Radiotherapy, High-Energy
KW - Stents
KW - Strontium Radioisotopes/therapeutic use
KW - Vascular Diseases/radiotherapy
KW - Yttrium Radioisotopes/therapeutic use
U2 - 10.1088/0031-9155/51/23/002
DO - 10.1088/0031-9155/51/23/002
M3 - SCORING: Journal article
C2 - 17110764
VL - 51
SP - 5977
EP - 5986
JO - PHYS MED BIOL
JF - PHYS MED BIOL
SN - 0031-9155
IS - 23
ER -
