Benzodiazepine und Z-Substanzen – Analyse der kassenärztlichen Verschreibungen von 2006 bis 2015

TY - JOUR

T1 - Benzodiazepine und Z-Substanzen – Analyse der kassenärztlichen Verschreibungen von 2006 bis 2015

AU - Verthein, Uwe

AU - Buth, Sven

AU - Holzbach, Rüdiger

AU - Neumann-Runde, Eike

AU - Martens, Marcus-S

N1 - © Georg Thieme Verlag KG Stuttgart · New York.

PY - 2019/10

Y1 - 2019/10

N2 - OBJECTIVE: The majority of medication-dependent persons uses sedatives and hypnotics for many years. In this study we describe trends of benzodiazepine and z-drug prescriptions over a 10-years period.METHODS: Prescriptions from 2006 to 2015 (based on German statutory health insurances) from the North German Pharmacy Computing Centre (NARZ) were analysed for the Federal states Schleswig-Holstein, Hamburg, Lower Saxony and Bremen. Data were classified as appropriate (in accordance with the guideline) or inappropriate/risky prescription patterns.RESULTS: In a 10-years period 1.64 Million patients received benzodiazepine and/or z-drug prescriptions. Two thirds were women (65.3 %). More than half were 60 years or older. The percentage of patients with appropriate prescriptions (less than 2 months) increased from 51.7 % in 2006 to 60.2 % in 2015. The rate of inappropriate or risky prescription patterns which can be indicative of misuse or dependence dropped from 34.8 % in 2006 to 27.1 % in 2015.CONCLUSION: Over the past years the amount of inappropriate or risky benzodiazepine and z-drug prescriptions (which are not in accordance with the guideline) among patients with statutory health insurance is steadily decreasing. However, two fifths of the patients still received prescriptions for long-term intake or in higher doses. It remains unclear to what extent private prescriptions are used for inappropriate or long-term prescriptions of benzodiazepines and z-drugs.

AB - OBJECTIVE: The majority of medication-dependent persons uses sedatives and hypnotics for many years. In this study we describe trends of benzodiazepine and z-drug prescriptions over a 10-years period.METHODS: Prescriptions from 2006 to 2015 (based on German statutory health insurances) from the North German Pharmacy Computing Centre (NARZ) were analysed for the Federal states Schleswig-Holstein, Hamburg, Lower Saxony and Bremen. Data were classified as appropriate (in accordance with the guideline) or inappropriate/risky prescription patterns.RESULTS: In a 10-years period 1.64 Million patients received benzodiazepine and/or z-drug prescriptions. Two thirds were women (65.3 %). More than half were 60 years or older. The percentage of patients with appropriate prescriptions (less than 2 months) increased from 51.7 % in 2006 to 60.2 % in 2015. The rate of inappropriate or risky prescription patterns which can be indicative of misuse or dependence dropped from 34.8 % in 2006 to 27.1 % in 2015.CONCLUSION: Over the past years the amount of inappropriate or risky benzodiazepine and z-drug prescriptions (which are not in accordance with the guideline) among patients with statutory health insurance is steadily decreasing. However, two fifths of the patients still received prescriptions for long-term intake or in higher doses. It remains unclear to what extent private prescriptions are used for inappropriate or long-term prescriptions of benzodiazepines and z-drugs.

KW - Benzodiazepines/administration & dosage

KW - Drug Prescriptions

KW - Female

KW - Germany

KW - Humans

KW - Hypnotics and Sedatives/administration & dosage

KW - Inappropriate Prescribing

KW - Male

KW - Middle Aged

KW - Practice Patterns, Physicians'

U2 - 10.1055/a-0961-2371

DO - 10.1055/a-0961-2371

M3 - SCORING: Zeitschriftenaufsatz

C2 - 31412372

VL - 46

SP - 399

EP - 405

JO - PSYCHIAT PRAX

JF - PSYCHIAT PRAX

SN - 0303-4259

IS - 7

ER -