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Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies

Standard

Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies. / Schneeberger, Yvonne; Sarwari, Harun; Köll, Benedikt; Demal, Till J; Bhadra, Oliver D; von der Heide, Ina; Hannen, Laura; Grundmann, David; Voigtländer, Lisa; Waldschmidt, Lara; Schirmer, Johannes; Pecha, Simon; Schofer, Niklas; Sörensen, Nils; Blankenberg, Stefan; Reichenspurner, Hermann; Conradi, Lenard; Seiffert, Moritz; Schaefer, Andreas.

In: CATHETER CARDIO INTE, Vol. 103, No. 1, 01.2024, p. 194-201.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Schneeberger, Y, Sarwari, H, Köll, B, Demal, TJ, Bhadra, OD, von der Heide, I, Hannen, L, Grundmann, D, Voigtländer, L, Waldschmidt, L, Schirmer, J, Pecha, S, Schofer, N, Sörensen, N, Blankenberg, S, Reichenspurner, H, Conradi, L, Seiffert, M & Schaefer, A 2024, 'Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies', CATHETER CARDIO INTE, vol. 103, no. 1, pp. 194-201. https://doi.org/10.1002/ccd.30922

APA

Schneeberger, Y., Sarwari, H., Köll, B., Demal, T. J., Bhadra, O. D., von der Heide, I., Hannen, L., Grundmann, D., Voigtländer, L., Waldschmidt, L., Schirmer, J., Pecha, S., Schofer, N., Sörensen, N., Blankenberg, S., Reichenspurner, H., Conradi, L., Seiffert, M., & Schaefer, A. (2024). Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies. CATHETER CARDIO INTE, 103(1), 194-201. https://doi.org/10.1002/ccd.30922

Vancouver

Schneeberger Y, Sarwari H, Köll B, Demal TJ, Bhadra OD, von der Heide I et al. Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies. CATHETER CARDIO INTE. 2024 Jan;103(1):194-201. https://doi.org/10.1002/ccd.30922

Bibtex

@article{f90a565d22854e3391c3801421e527cc,
title = "Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies",
abstract = "OBJECTIVES: Transcatheter aortic valve implantation (TAVI) using balloon-expandable (BE) transcatheter heart valves (THV) in aortic annuli above 29 mm includes particular procedural steps, mainly involving overfilling of the deployment balloon. Data on overfilling strategies in clinical daily practice is scarce. We herein aimed for a retrospective description of utilized overfilling strategies in those patients.METHODS: Between January 2016 and December 2022, 45 patients (100% male, 76.9 ± 6.1 years) received TAVI in aortic annuli above 29 mm using a BE THV. Overfilling volumina of the deployment balloon were left to operators' discretion. Clinical and multislice computed tomography data were retrospectively collected. Clinical endpoints were adjudicated in accordance with the updated standardized VARC-3 definitions.RESULTS: Profound overfilling (+4/5 mL) was used in patients with a mild calcium burden (˂750 mm³) even in aortic annuli of 29.0-30.0 mm. Nominal/slight overfilling (+1 mL) was used in aortic annuli up to 32.5 mm but an intermediate to severe calcific burden (>750-3200 mm³). Accordingly, a low calcification group (˂750 mm³, n = 17) compared to a significant calcification group (≥750 mm³, n = 28), presented with higher overfilling volumina (2.1 ± 1.4 vs. 0.8 ± 1.0; p ˂ 0.001), although aortic annulus diameter was not different (29.8 ± 0.8 vs. 29.9 ± 0.9 mm; p = 0.7). All-cause 30-day mortality was 0%. Device success was 97.8%. Transvalvular mean pressure gradient at discharge was 9.5 ± 3.6 mmHg. No case of PVL >mild was documented.CONCLUSION: Extent of overfilling of the deployment balloon largely depends on calcification burden in addition to aortic annulus diameter with significant and profound overfilling particularly in patients with a calcification burden of the aortic valve complex ˂750 mm³.",
author = "Yvonne Schneeberger and Harun Sarwari and Benedikt K{\"o}ll and Demal, {Till J} and Bhadra, {Oliver D} and {von der Heide}, Ina and Laura Hannen and David Grundmann and Lisa Voigtl{\"a}nder and Lara Waldschmidt and Johannes Schirmer and Simon Pecha and Niklas Schofer and Nils S{\"o}rensen and Stefan Blankenberg and Hermann Reichenspurner and Lenard Conradi and Moritz Seiffert and Andreas Schaefer",
note = "{\textcopyright} 2023 Wiley Periodicals LLC.",
year = "2024",
month = jan,
doi = "10.1002/ccd.30922",
language = "English",
volume = "103",
pages = "194--201",
journal = "CATHETER CARDIO INTE",
issn = "1522-1946",
publisher = "Wiley-Liss Inc.",
number = "1",

}

RIS

TY - JOUR

T1 - Balloon-expandable transcatheter heart valves for treatment of aortic valve stenosis in patients with large aortic annuli: Evaluation of deployment balloon overfilling strategies

AU - Schneeberger, Yvonne

AU - Sarwari, Harun

AU - Köll, Benedikt

AU - Demal, Till J

AU - Bhadra, Oliver D

AU - von der Heide, Ina

AU - Hannen, Laura

AU - Grundmann, David

AU - Voigtländer, Lisa

AU - Waldschmidt, Lara

AU - Schirmer, Johannes

AU - Pecha, Simon

AU - Schofer, Niklas

AU - Sörensen, Nils

AU - Blankenberg, Stefan

AU - Reichenspurner, Hermann

AU - Conradi, Lenard

AU - Seiffert, Moritz

AU - Schaefer, Andreas

N1 - © 2023 Wiley Periodicals LLC.

PY - 2024/1

Y1 - 2024/1

N2 - OBJECTIVES: Transcatheter aortic valve implantation (TAVI) using balloon-expandable (BE) transcatheter heart valves (THV) in aortic annuli above 29 mm includes particular procedural steps, mainly involving overfilling of the deployment balloon. Data on overfilling strategies in clinical daily practice is scarce. We herein aimed for a retrospective description of utilized overfilling strategies in those patients.METHODS: Between January 2016 and December 2022, 45 patients (100% male, 76.9 ± 6.1 years) received TAVI in aortic annuli above 29 mm using a BE THV. Overfilling volumina of the deployment balloon were left to operators' discretion. Clinical and multislice computed tomography data were retrospectively collected. Clinical endpoints were adjudicated in accordance with the updated standardized VARC-3 definitions.RESULTS: Profound overfilling (+4/5 mL) was used in patients with a mild calcium burden (˂750 mm³) even in aortic annuli of 29.0-30.0 mm. Nominal/slight overfilling (+1 mL) was used in aortic annuli up to 32.5 mm but an intermediate to severe calcific burden (>750-3200 mm³). Accordingly, a low calcification group (˂750 mm³, n = 17) compared to a significant calcification group (≥750 mm³, n = 28), presented with higher overfilling volumina (2.1 ± 1.4 vs. 0.8 ± 1.0; p ˂ 0.001), although aortic annulus diameter was not different (29.8 ± 0.8 vs. 29.9 ± 0.9 mm; p = 0.7). All-cause 30-day mortality was 0%. Device success was 97.8%. Transvalvular mean pressure gradient at discharge was 9.5 ± 3.6 mmHg. No case of PVL >mild was documented.CONCLUSION: Extent of overfilling of the deployment balloon largely depends on calcification burden in addition to aortic annulus diameter with significant and profound overfilling particularly in patients with a calcification burden of the aortic valve complex ˂750 mm³.

AB - OBJECTIVES: Transcatheter aortic valve implantation (TAVI) using balloon-expandable (BE) transcatheter heart valves (THV) in aortic annuli above 29 mm includes particular procedural steps, mainly involving overfilling of the deployment balloon. Data on overfilling strategies in clinical daily practice is scarce. We herein aimed for a retrospective description of utilized overfilling strategies in those patients.METHODS: Between January 2016 and December 2022, 45 patients (100% male, 76.9 ± 6.1 years) received TAVI in aortic annuli above 29 mm using a BE THV. Overfilling volumina of the deployment balloon were left to operators' discretion. Clinical and multislice computed tomography data were retrospectively collected. Clinical endpoints were adjudicated in accordance with the updated standardized VARC-3 definitions.RESULTS: Profound overfilling (+4/5 mL) was used in patients with a mild calcium burden (˂750 mm³) even in aortic annuli of 29.0-30.0 mm. Nominal/slight overfilling (+1 mL) was used in aortic annuli up to 32.5 mm but an intermediate to severe calcific burden (>750-3200 mm³). Accordingly, a low calcification group (˂750 mm³, n = 17) compared to a significant calcification group (≥750 mm³, n = 28), presented with higher overfilling volumina (2.1 ± 1.4 vs. 0.8 ± 1.0; p ˂ 0.001), although aortic annulus diameter was not different (29.8 ± 0.8 vs. 29.9 ± 0.9 mm; p = 0.7). All-cause 30-day mortality was 0%. Device success was 97.8%. Transvalvular mean pressure gradient at discharge was 9.5 ± 3.6 mmHg. No case of PVL >mild was documented.CONCLUSION: Extent of overfilling of the deployment balloon largely depends on calcification burden in addition to aortic annulus diameter with significant and profound overfilling particularly in patients with a calcification burden of the aortic valve complex ˂750 mm³.

U2 - 10.1002/ccd.30922

DO - 10.1002/ccd.30922

M3 - SCORING: Journal article

C2 - 38037296

VL - 103

SP - 194

EP - 201

JO - CATHETER CARDIO INTE

JF - CATHETER CARDIO INTE

SN - 1522-1946

IS - 1

ER -