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Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations

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Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations : hereditary persistence of α-fetoprotein is an important and benign differential diagnosis! / Bonfig, Walter; Hempel, Maja; Teichert-von Lüttichau, Irene; Liptay, Susanne; Burdach, Stefan.

In: J PEDIAT HEMATOL ONC, Vol. 34, No. 7, 10.2012, p. e301-3.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Bonfig, W, Hempel, M, Teichert-von Lüttichau, I, Liptay, S & Burdach, S 2012, 'Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations: hereditary persistence of α-fetoprotein is an important and benign differential diagnosis!', J PEDIAT HEMATOL ONC, vol. 34, no. 7, pp. e301-3. https://doi.org/10.1097/MPH.0b013e3182441256

APA

Bonfig, W., Hempel, M., Teichert-von Lüttichau, I., Liptay, S., & Burdach, S. (2012). Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations: hereditary persistence of α-fetoprotein is an important and benign differential diagnosis! J PEDIAT HEMATOL ONC, 34(7), e301-3. https://doi.org/10.1097/MPH.0b013e3182441256

Vancouver

Bonfig W, Hempel M, Teichert-von Lüttichau I, Liptay S, Burdach S. Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations: hereditary persistence of α-fetoprotein is an important and benign differential diagnosis! J PEDIAT HEMATOL ONC. 2012 Oct;34(7):e301-3. https://doi.org/10.1097/MPH.0b013e3182441256

Bibtex

@article{66ccdf03f7534be498109b750375119f,
title = "Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations: hereditary persistence of α-fetoprotein is an important and benign differential diagnosis!",
abstract = "BACKGROUND: Hereditary persistence of α-fetoprotein (AFP) is a rare but benign condition.OBSERVATION: A 13-year-old girl presented with dysmenorrhoic complaints and irregular cycles. Diagnostic workup revealed a cystic lesion of the ovary and elevated AFP; β-human chorionic gonadotrophin was negative. Right-sided ovarectomy was performed. Postsurgery AFP concentration did not decline. The patient underwent further diagnostic workup with negative results. Histology revealed follicular cysts but no tumor. Finally, hereditary persistence of AFP was suspected and AFP testing was performed in the family.CONCLUSIONS: It is important to include hereditary persistence of AFP in the differential diagnosis of elevated AFP concentrations to avoid harmful procedures.",
keywords = "Adolescent, Diagnosis, Differential, Female, Humans, Ovarian Cysts, Ovarian Neoplasms, Ovariectomy, alpha-Fetoproteins",
author = "Walter Bonfig and Maja Hempel and {Teichert-von L{\"u}ttichau}, Irene and Susanne Liptay and Stefan Burdach",
year = "2012",
month = oct,
doi = "10.1097/MPH.0b013e3182441256",
language = "English",
volume = "34",
pages = "e301--3",
journal = "J PEDIAT HEMATOL ONC",
issn = "1077-4114",
publisher = "Raven Press",
number = "7",

}

RIS

TY - JOUR

T1 - Avoiding harmful procedures in patients with elevated α-fetoprotein concentrations

T2 - hereditary persistence of α-fetoprotein is an important and benign differential diagnosis!

AU - Bonfig, Walter

AU - Hempel, Maja

AU - Teichert-von Lüttichau, Irene

AU - Liptay, Susanne

AU - Burdach, Stefan

PY - 2012/10

Y1 - 2012/10

N2 - BACKGROUND: Hereditary persistence of α-fetoprotein (AFP) is a rare but benign condition.OBSERVATION: A 13-year-old girl presented with dysmenorrhoic complaints and irregular cycles. Diagnostic workup revealed a cystic lesion of the ovary and elevated AFP; β-human chorionic gonadotrophin was negative. Right-sided ovarectomy was performed. Postsurgery AFP concentration did not decline. The patient underwent further diagnostic workup with negative results. Histology revealed follicular cysts but no tumor. Finally, hereditary persistence of AFP was suspected and AFP testing was performed in the family.CONCLUSIONS: It is important to include hereditary persistence of AFP in the differential diagnosis of elevated AFP concentrations to avoid harmful procedures.

AB - BACKGROUND: Hereditary persistence of α-fetoprotein (AFP) is a rare but benign condition.OBSERVATION: A 13-year-old girl presented with dysmenorrhoic complaints and irregular cycles. Diagnostic workup revealed a cystic lesion of the ovary and elevated AFP; β-human chorionic gonadotrophin was negative. Right-sided ovarectomy was performed. Postsurgery AFP concentration did not decline. The patient underwent further diagnostic workup with negative results. Histology revealed follicular cysts but no tumor. Finally, hereditary persistence of AFP was suspected and AFP testing was performed in the family.CONCLUSIONS: It is important to include hereditary persistence of AFP in the differential diagnosis of elevated AFP concentrations to avoid harmful procedures.

KW - Adolescent

KW - Diagnosis, Differential

KW - Female

KW - Humans

KW - Ovarian Cysts

KW - Ovarian Neoplasms

KW - Ovariectomy

KW - alpha-Fetoproteins

U2 - 10.1097/MPH.0b013e3182441256

DO - 10.1097/MPH.0b013e3182441256

M3 - SCORING: Journal article

C2 - 22430587

VL - 34

SP - e301-3

JO - J PEDIAT HEMATOL ONC

JF - J PEDIAT HEMATOL ONC

SN - 1077-4114

IS - 7

ER -