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Autophagy in cardiomyopathies

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Autophagy in cardiomyopathies. / Zech, Antonia Theresa Luisa; Singh, Sonia; Schlossarek, Saskia; Carrier, Lucie.

In: BBA-MOL CELL RES, Vol. 1867, No. 3, 03.2020, p. 118432.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Zech, ATL, Singh, S, Schlossarek, S & Carrier, L 2020, 'Autophagy in cardiomyopathies', BBA-MOL CELL RES, vol. 1867, no. 3, pp. 118432. https://doi.org/10.1016/j.bbamcr.2019.01.013

APA

Zech, A. T. L., Singh, S., Schlossarek, S., & Carrier, L. (2020). Autophagy in cardiomyopathies. BBA-MOL CELL RES, 1867(3), 118432. https://doi.org/10.1016/j.bbamcr.2019.01.013

Vancouver

Zech ATL, Singh S, Schlossarek S, Carrier L. Autophagy in cardiomyopathies. BBA-MOL CELL RES. 2020 Mar;1867(3):118432. https://doi.org/10.1016/j.bbamcr.2019.01.013

Bibtex

@article{11e618dfdb4544fcb7dba4806b2535e2,
title = "Autophagy in cardiomyopathies",
abstract = "Autophagy (greek auto: self; phagein: eating) is a highly conserved process within eukaryotes that degrades long-lived proteins and organelles within lysosomes. Its accurate and constant operation in basal conditions ensures cellular homeostasis by degrading damaged cellular components and thereby acting not only as a quality control but as well as an energy supplier. An increasing body of evidence indicates a major role of autophagy in the regulation of cardiac homeostasis and function. In this review, we describe the different forms of mammalian autophagy, their regulations and monitoring with a specific emphasis on the heart. Furthermore, we address the role of autophagy in several forms of cardiomyopathy and the options for therapy.",
author = "Zech, {Antonia Theresa Luisa} and Sonia Singh and Saskia Schlossarek and Lucie Carrier",
year = "2020",
month = mar,
doi = "10.1016/j.bbamcr.2019.01.013",
language = "English",
volume = "1867",
pages = "118432",
journal = "BBA-MOL CELL RES",
issn = "0167-4889",
publisher = "Elsevier",
number = "3",

}

RIS

TY - JOUR

T1 - Autophagy in cardiomyopathies

AU - Zech, Antonia Theresa Luisa

AU - Singh, Sonia

AU - Schlossarek, Saskia

AU - Carrier, Lucie

PY - 2020/3

Y1 - 2020/3

N2 - Autophagy (greek auto: self; phagein: eating) is a highly conserved process within eukaryotes that degrades long-lived proteins and organelles within lysosomes. Its accurate and constant operation in basal conditions ensures cellular homeostasis by degrading damaged cellular components and thereby acting not only as a quality control but as well as an energy supplier. An increasing body of evidence indicates a major role of autophagy in the regulation of cardiac homeostasis and function. In this review, we describe the different forms of mammalian autophagy, their regulations and monitoring with a specific emphasis on the heart. Furthermore, we address the role of autophagy in several forms of cardiomyopathy and the options for therapy.

AB - Autophagy (greek auto: self; phagein: eating) is a highly conserved process within eukaryotes that degrades long-lived proteins and organelles within lysosomes. Its accurate and constant operation in basal conditions ensures cellular homeostasis by degrading damaged cellular components and thereby acting not only as a quality control but as well as an energy supplier. An increasing body of evidence indicates a major role of autophagy in the regulation of cardiac homeostasis and function. In this review, we describe the different forms of mammalian autophagy, their regulations and monitoring with a specific emphasis on the heart. Furthermore, we address the role of autophagy in several forms of cardiomyopathy and the options for therapy.

U2 - 10.1016/j.bbamcr.2019.01.013

DO - 10.1016/j.bbamcr.2019.01.013

M3 - SCORING: Review article

VL - 1867

SP - 118432

JO - BBA-MOL CELL RES

JF - BBA-MOL CELL RES

SN - 0167-4889

IS - 3

ER -