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Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye?

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Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye? / Psychogios, Marios-Nikos; Sporns, Peter B; Ospel, Johanna; Katsanos, Aristeidis H; Kabiri, Reza; Flottmann, Fabian A; Menon, Bijoy K; Horn, Mackenzie; Liebeskind, David S; Honda, Tristan; Ribo, Marc; Ruiz, Manuel Requena; Kabbasch, Christoph; Lichtenstein, Thorsten; Maurer, Christoph J; Berlis, Ansgar; Hellstern, Victoria; Henkes, Hans; Möhlenbruch, Markus A; Seker, Fatih; Ernst, Marielle S; Liman, Jan; Tsivgoulis, Georgios; Brehm, Alex.

In: CLIN NEURORADIOL, Vol. 31, No. 2, 06.2021, p. 499-506.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Psychogios, M-N, Sporns, PB, Ospel, J, Katsanos, AH, Kabiri, R, Flottmann, FA, Menon, BK, Horn, M, Liebeskind, DS, Honda, T, Ribo, M, Ruiz, MR, Kabbasch, C, Lichtenstein, T, Maurer, CJ, Berlis, A, Hellstern, V, Henkes, H, Möhlenbruch, MA, Seker, F, Ernst, MS, Liman, J, Tsivgoulis, G & Brehm, A 2021, 'Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye?', CLIN NEURORADIOL, vol. 31, no. 2, pp. 499-506. https://doi.org/10.1007/s00062-020-00974-3

APA

Psychogios, M-N., Sporns, P. B., Ospel, J., Katsanos, A. H., Kabiri, R., Flottmann, F. A., Menon, B. K., Horn, M., Liebeskind, D. S., Honda, T., Ribo, M., Ruiz, M. R., Kabbasch, C., Lichtenstein, T., Maurer, C. J., Berlis, A., Hellstern, V., Henkes, H., Möhlenbruch, M. A., ... Brehm, A. (2021). Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye? CLIN NEURORADIOL, 31(2), 499-506. https://doi.org/10.1007/s00062-020-00974-3

Vancouver

Psychogios M-N, Sporns PB, Ospel J, Katsanos AH, Kabiri R, Flottmann FA et al. Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye? CLIN NEURORADIOL. 2021 Jun;31(2):499-506. https://doi.org/10.1007/s00062-020-00974-3

Bibtex

@article{6858cfe9eeed48a0879a6c2e1aa557f2,
title = "Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye?",
abstract = "PURPOSE: Use of automated perfusion software has gained importance for imaging of stroke patients for mechanical thrombectomy (MT). We aim to compare four perfusion software packages: 1) with respect to their association with 3‑month functional outcome after successful reperfusion with MT in comparison to visual Cerebral Blood Volume - Alberta Stroke Program Early CT Score (CBV-ASPECTS) and collateral scoring and 2) with respect to their agreement in estimation of core and penumbra volume.METHODS: This retrospective, multicenter cohort study (2015-2019) analyzed data from 8 centers. We included patients who were functionally independent before and underwent successful MT of the middle cerebral artery. Primary outcome measurements were the relationship of core and penumbra volume calculated by each software, qualitative assessment of collaterals and CBV-APECTS with 3‑month functional outcome and disability (modified Rankin scale >2). Quantitative differences between perfusion software measurements were also assessed.RESULTS: A total of 215 patients (57% women, median age 77 years) from 8 centers fulfilled the inclusion criteria. Multivariable analyses showed a significant association of RAPID core (common odds ratio, cOR 1.02; p = 0.015), CBV-ASPECTS (cOR 0.78; p = 0.007) and collaterals (cOR 0.78; p = 0.001) with 3‑month functional outcome (shift analysis), while RAPID core (OR 1.02; p = 0.018), CBV-ASPECTS (OR 0.77; p = 0.024), collaterals (OR 0.78; p = 0.007) and OLEA core (OR 1.02; p = 0.029) were significantly associated with 3‑month functional disability. Mean differences on core estimates between VEOcore and RAPID were 13.4 ml, between syngo.via and RAPID 30.0 ml and between OLEA and RAPID -3.2 ml.CONCLUSION: Collateral scoring, CBV-ASPECTS and RAPID were independently associated with functional outcome at 90 days. Core and Penumbra estimates using automated software packages varied significantly and should therefore be used with caution.",
author = "Marios-Nikos Psychogios and Sporns, {Peter B} and Johanna Ospel and Katsanos, {Aristeidis H} and Reza Kabiri and Flottmann, {Fabian A} and Menon, {Bijoy K} and Mackenzie Horn and Liebeskind, {David S} and Tristan Honda and Marc Ribo and Ruiz, {Manuel Requena} and Christoph Kabbasch and Thorsten Lichtenstein and Maurer, {Christoph J} and Ansgar Berlis and Victoria Hellstern and Hans Henkes and M{\"o}hlenbruch, {Markus A} and Fatih Seker and Ernst, {Marielle S} and Jan Liman and Georgios Tsivgoulis and Alex Brehm",
year = "2021",
month = jun,
doi = "10.1007/s00062-020-00974-3",
language = "English",
volume = "31",
pages = "499--506",
journal = "CLIN NEURORADIOL",
issn = "1869-1439",
publisher = "Springer Heidelberg",
number = "2",

}

RIS

TY - JOUR

T1 - Automated Perfusion Calculations vs. Visual Scoring of Collaterals and CBV-ASPECTS: Has the Machine Surpassed the Eye?

AU - Psychogios, Marios-Nikos

AU - Sporns, Peter B

AU - Ospel, Johanna

AU - Katsanos, Aristeidis H

AU - Kabiri, Reza

AU - Flottmann, Fabian A

AU - Menon, Bijoy K

AU - Horn, Mackenzie

AU - Liebeskind, David S

AU - Honda, Tristan

AU - Ribo, Marc

AU - Ruiz, Manuel Requena

AU - Kabbasch, Christoph

AU - Lichtenstein, Thorsten

AU - Maurer, Christoph J

AU - Berlis, Ansgar

AU - Hellstern, Victoria

AU - Henkes, Hans

AU - Möhlenbruch, Markus A

AU - Seker, Fatih

AU - Ernst, Marielle S

AU - Liman, Jan

AU - Tsivgoulis, Georgios

AU - Brehm, Alex

PY - 2021/6

Y1 - 2021/6

N2 - PURPOSE: Use of automated perfusion software has gained importance for imaging of stroke patients for mechanical thrombectomy (MT). We aim to compare four perfusion software packages: 1) with respect to their association with 3‑month functional outcome after successful reperfusion with MT in comparison to visual Cerebral Blood Volume - Alberta Stroke Program Early CT Score (CBV-ASPECTS) and collateral scoring and 2) with respect to their agreement in estimation of core and penumbra volume.METHODS: This retrospective, multicenter cohort study (2015-2019) analyzed data from 8 centers. We included patients who were functionally independent before and underwent successful MT of the middle cerebral artery. Primary outcome measurements were the relationship of core and penumbra volume calculated by each software, qualitative assessment of collaterals and CBV-APECTS with 3‑month functional outcome and disability (modified Rankin scale >2). Quantitative differences between perfusion software measurements were also assessed.RESULTS: A total of 215 patients (57% women, median age 77 years) from 8 centers fulfilled the inclusion criteria. Multivariable analyses showed a significant association of RAPID core (common odds ratio, cOR 1.02; p = 0.015), CBV-ASPECTS (cOR 0.78; p = 0.007) and collaterals (cOR 0.78; p = 0.001) with 3‑month functional outcome (shift analysis), while RAPID core (OR 1.02; p = 0.018), CBV-ASPECTS (OR 0.77; p = 0.024), collaterals (OR 0.78; p = 0.007) and OLEA core (OR 1.02; p = 0.029) were significantly associated with 3‑month functional disability. Mean differences on core estimates between VEOcore and RAPID were 13.4 ml, between syngo.via and RAPID 30.0 ml and between OLEA and RAPID -3.2 ml.CONCLUSION: Collateral scoring, CBV-ASPECTS and RAPID were independently associated with functional outcome at 90 days. Core and Penumbra estimates using automated software packages varied significantly and should therefore be used with caution.

AB - PURPOSE: Use of automated perfusion software has gained importance for imaging of stroke patients for mechanical thrombectomy (MT). We aim to compare four perfusion software packages: 1) with respect to their association with 3‑month functional outcome after successful reperfusion with MT in comparison to visual Cerebral Blood Volume - Alberta Stroke Program Early CT Score (CBV-ASPECTS) and collateral scoring and 2) with respect to their agreement in estimation of core and penumbra volume.METHODS: This retrospective, multicenter cohort study (2015-2019) analyzed data from 8 centers. We included patients who were functionally independent before and underwent successful MT of the middle cerebral artery. Primary outcome measurements were the relationship of core and penumbra volume calculated by each software, qualitative assessment of collaterals and CBV-APECTS with 3‑month functional outcome and disability (modified Rankin scale >2). Quantitative differences between perfusion software measurements were also assessed.RESULTS: A total of 215 patients (57% women, median age 77 years) from 8 centers fulfilled the inclusion criteria. Multivariable analyses showed a significant association of RAPID core (common odds ratio, cOR 1.02; p = 0.015), CBV-ASPECTS (cOR 0.78; p = 0.007) and collaterals (cOR 0.78; p = 0.001) with 3‑month functional outcome (shift analysis), while RAPID core (OR 1.02; p = 0.018), CBV-ASPECTS (OR 0.77; p = 0.024), collaterals (OR 0.78; p = 0.007) and OLEA core (OR 1.02; p = 0.029) were significantly associated with 3‑month functional disability. Mean differences on core estimates between VEOcore and RAPID were 13.4 ml, between syngo.via and RAPID 30.0 ml and between OLEA and RAPID -3.2 ml.CONCLUSION: Collateral scoring, CBV-ASPECTS and RAPID were independently associated with functional outcome at 90 days. Core and Penumbra estimates using automated software packages varied significantly and should therefore be used with caution.

U2 - 10.1007/s00062-020-00974-3

DO - 10.1007/s00062-020-00974-3

M3 - SCORING: Journal article

C2 - 33216157

VL - 31

SP - 499

EP - 506

JO - CLIN NEURORADIOL

JF - CLIN NEURORADIOL

SN - 1869-1439

IS - 2

ER -