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Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance

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Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance. / Sebode, Marcial; Weiler-Normann, Christina; Liwinski, Timur; Schramm, Christoph.

In: FRONT IMMUNOL, Vol. 9, 2018, p. 609.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Sebode, M, Weiler-Normann, C, Liwinski, T & Schramm, C 2018, 'Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance', FRONT IMMUNOL, vol. 9, pp. 609. https://doi.org/10.3389/fimmu.2018.00609

APA

Sebode, M., Weiler-Normann, C., Liwinski, T., & Schramm, C. (2018). Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance. FRONT IMMUNOL, 9, 609. https://doi.org/10.3389/fimmu.2018.00609

Vancouver

Sebode M, Weiler-Normann C, Liwinski T, Schramm C. Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance. FRONT IMMUNOL. 2018;9:609. https://doi.org/10.3389/fimmu.2018.00609

Bibtex

@article{0ce087e7dc394b269d4d4f0393757dfd,
title = "Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance",
abstract = "Testing for liver-related autoantibodies should be included in the workup of patients with hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not disease specific, their determination is a prerequisite to diagnose autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC), and they are components of the diagnostic scoring system in these diseases. In primary sclerosing cholangitis (PSC), on the other hand, autoantibodies are frequently present but play a minor role in establishing the diagnosis. In PSC, however, data on antibodies suggest a link between disease pathogenesis and the intestinal microbiota. This review will focus on practical aspects of antibody testing in the three major autoimmune liver diseases AIH, PBC, and PSC.",
keywords = "Journal Article, Review",
author = "Marcial Sebode and Christina Weiler-Normann and Timur Liwinski and Christoph Schramm",
year = "2018",
doi = "10.3389/fimmu.2018.00609",
language = "English",
volume = "9",
pages = "609",
journal = "FRONT IMMUNOL",
issn = "1664-3224",
publisher = "Lausanne : Frontiers Research Foundation",

}

RIS

TY - JOUR

T1 - Autoantibodies in Autoimmune Liver Disease-Clinical and Diagnostic Relevance

AU - Sebode, Marcial

AU - Weiler-Normann, Christina

AU - Liwinski, Timur

AU - Schramm, Christoph

PY - 2018

Y1 - 2018

N2 - Testing for liver-related autoantibodies should be included in the workup of patients with hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not disease specific, their determination is a prerequisite to diagnose autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC), and they are components of the diagnostic scoring system in these diseases. In primary sclerosing cholangitis (PSC), on the other hand, autoantibodies are frequently present but play a minor role in establishing the diagnosis. In PSC, however, data on antibodies suggest a link between disease pathogenesis and the intestinal microbiota. This review will focus on practical aspects of antibody testing in the three major autoimmune liver diseases AIH, PBC, and PSC.

AB - Testing for liver-related autoantibodies should be included in the workup of patients with hepatitis or cholestasis of unknown origin. Although most of these autoantibodies are not disease specific, their determination is a prerequisite to diagnose autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC), and they are components of the diagnostic scoring system in these diseases. In primary sclerosing cholangitis (PSC), on the other hand, autoantibodies are frequently present but play a minor role in establishing the diagnosis. In PSC, however, data on antibodies suggest a link between disease pathogenesis and the intestinal microbiota. This review will focus on practical aspects of antibody testing in the three major autoimmune liver diseases AIH, PBC, and PSC.

KW - Journal Article

KW - Review

U2 - 10.3389/fimmu.2018.00609

DO - 10.3389/fimmu.2018.00609

M3 - SCORING: Review article

C2 - 29636752

VL - 9

SP - 609

JO - FRONT IMMUNOL

JF - FRONT IMMUNOL

SN - 1664-3224

ER -