Atrial natriuretic peptide-induced stimulation of cyclic GMP formation by isolated bovine luteal cells.

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Atrial natriuretic peptide-induced stimulation of cyclic GMP formation by isolated bovine luteal cells. / Brunswig, B; Budnik, Lygia Therese; Mukhopadhyay, A K.

In: J Reprod Fertil, Vol. 86, No. 2, 2, 1989, p. 665-669.

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@article{5b6fa83cf2914b058f4cba543335430d,
title = "Atrial natriuretic peptide-induced stimulation of cyclic GMP formation by isolated bovine luteal cells.",
abstract = "Incubation of bovine luteal cells with an atrial natriuretic peptide (rat atriopeptin II, rAP-II) did not affect hCG-stimulated or basal cyclic AMP accumulation and progesterone production, but cyclic GMP formation was stimulated by rAP-II in a dose-dependent manner, being maximally stimulatory in the nanomolar range. This stimulatory influence of rAP-II on cyclic GMP formation results from a specific stimulation of particulate guanylate cyclase. We suggest that, although rAP-II mediated cyclic GMP formation can be demonstrated in bovine luteal cells, there appear to be no acute effects of the atrial peptide on the regulation of progesterone production by these cells.",
author = "B Brunswig and Budnik, {Lygia Therese} and Mukhopadhyay, {A K}",
year = "1989",
language = "Deutsch",
volume = "86",
pages = "665--669",
journal = "J Reprod Fertil",
issn = "0022-4251",
publisher = "Society for Reproduction and Fertility",
number = "2",

}

RIS

TY - JOUR

T1 - Atrial natriuretic peptide-induced stimulation of cyclic GMP formation by isolated bovine luteal cells.

AU - Brunswig, B

AU - Budnik, Lygia Therese

AU - Mukhopadhyay, A K

PY - 1989

Y1 - 1989

N2 - Incubation of bovine luteal cells with an atrial natriuretic peptide (rat atriopeptin II, rAP-II) did not affect hCG-stimulated or basal cyclic AMP accumulation and progesterone production, but cyclic GMP formation was stimulated by rAP-II in a dose-dependent manner, being maximally stimulatory in the nanomolar range. This stimulatory influence of rAP-II on cyclic GMP formation results from a specific stimulation of particulate guanylate cyclase. We suggest that, although rAP-II mediated cyclic GMP formation can be demonstrated in bovine luteal cells, there appear to be no acute effects of the atrial peptide on the regulation of progesterone production by these cells.

AB - Incubation of bovine luteal cells with an atrial natriuretic peptide (rat atriopeptin II, rAP-II) did not affect hCG-stimulated or basal cyclic AMP accumulation and progesterone production, but cyclic GMP formation was stimulated by rAP-II in a dose-dependent manner, being maximally stimulatory in the nanomolar range. This stimulatory influence of rAP-II on cyclic GMP formation results from a specific stimulation of particulate guanylate cyclase. We suggest that, although rAP-II mediated cyclic GMP formation can be demonstrated in bovine luteal cells, there appear to be no acute effects of the atrial peptide on the regulation of progesterone production by these cells.

M3 - SCORING: Zeitschriftenaufsatz

VL - 86

SP - 665

EP - 669

JO - J Reprod Fertil

JF - J Reprod Fertil

SN - 0022-4251

IS - 2

M1 - 2

ER -