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Atrial fibrillation and prestroke cognitive impairment in stroke

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Atrial fibrillation and prestroke cognitive impairment in stroke. / Horstmann, Solveig; Rizos, Timolaos; Rauch, Geraldine; Fuchs, Maximilian; Arden, Cathrin; Veltkamp, Roland.

In: J NEUROL, Vol. 261, No. 3, 03.2014, p. 546-53.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Horstmann, S, Rizos, T, Rauch, G, Fuchs, M, Arden, C & Veltkamp, R 2014, 'Atrial fibrillation and prestroke cognitive impairment in stroke', J NEUROL, vol. 261, no. 3, pp. 546-53. https://doi.org/10.1007/s00415-013-7233-3

APA

Horstmann, S., Rizos, T., Rauch, G., Fuchs, M., Arden, C., & Veltkamp, R. (2014). Atrial fibrillation and prestroke cognitive impairment in stroke. J NEUROL, 261(3), 546-53. https://doi.org/10.1007/s00415-013-7233-3

Vancouver

Horstmann S, Rizos T, Rauch G, Fuchs M, Arden C, Veltkamp R. Atrial fibrillation and prestroke cognitive impairment in stroke. J NEUROL. 2014 Mar;261(3):546-53. https://doi.org/10.1007/s00415-013-7233-3

Bibtex

@article{6618a8574a824245a1cd010aee57309c,
title = "Atrial fibrillation and prestroke cognitive impairment in stroke",
abstract = "Dementia and atrial fibrillation (AF) are common comorbidities in stroke patients. The potential role of AF in cognitive impairment prior to a first stroke has yet not been characterized. The aim of our study was to evaluate the prevalence of prestroke cognitive impairment in stroke patients, and to identify whether AF is associated with prestroke cognitive impairment. In this prospective, single-center, explorative, observational study, consecutive patients with first ever transient ischemic attack (TIA), ischemic (IS) or hemorrhagic stroke (ICH) were included. For each patient cardiovascular risk factors and the National Institutes of Health Stroke Scale were recorded. Cognitive status prior to the stroke/TIA was assessed using the informant questionnaire on cognitive decline in the elderly (IQCODE). AF was diagnosed according to a standardised procedure that included the documented medical history, ECG upon admission, 24-h Holter-ECG, continuos ECG monitoring, and was categorized into paroxysmal and persistent. Logistic regression analysis was used to evaluate association of AF and prestroke cognitive impairment. A total of 788 patients were enrolled in our study. Of these, 548 (69.5 %) had an IS, TIA was present in 168 (21.3 %) and ICH in 72 (9.1 %) patients. Mean IQCODE was 3.1 (SD 0.4). Prestroke cognitive impairment (IQCODE ≥3.44) was detected in 96 (12.5 %) patients. Of these, 33 patients (4.3 %) were demented before the actual stroke event. AF was independently associated with prestroke cognitive impairment. Patients with an acute stroke frequently show a history of cognitive impairment before the event. AF is independently associated with prestroke cognitive impairment.",
keywords = "Aged, Atrial Fibrillation, Brain Ischemia, Cognition Disorders, Comorbidity, Female, Humans, Intracranial Hemorrhages, Ischemic Attack, Transient, Male, Middle Aged, Prevalence, Prospective Studies, Risk Factors, Stroke, Journal Article, Observational Study, Research Support, Non-U.S. Gov't",
author = "Solveig Horstmann and Timolaos Rizos and Geraldine Rauch and Maximilian Fuchs and Cathrin Arden and Roland Veltkamp",
year = "2014",
month = mar,
doi = "10.1007/s00415-013-7233-3",
language = "English",
volume = "261",
pages = "546--53",
journal = "J NEUROL",
issn = "0340-5354",
publisher = "D. Steinkopff-Verlag",
number = "3",

}

RIS

TY - JOUR

T1 - Atrial fibrillation and prestroke cognitive impairment in stroke

AU - Horstmann, Solveig

AU - Rizos, Timolaos

AU - Rauch, Geraldine

AU - Fuchs, Maximilian

AU - Arden, Cathrin

AU - Veltkamp, Roland

PY - 2014/3

Y1 - 2014/3

N2 - Dementia and atrial fibrillation (AF) are common comorbidities in stroke patients. The potential role of AF in cognitive impairment prior to a first stroke has yet not been characterized. The aim of our study was to evaluate the prevalence of prestroke cognitive impairment in stroke patients, and to identify whether AF is associated with prestroke cognitive impairment. In this prospective, single-center, explorative, observational study, consecutive patients with first ever transient ischemic attack (TIA), ischemic (IS) or hemorrhagic stroke (ICH) were included. For each patient cardiovascular risk factors and the National Institutes of Health Stroke Scale were recorded. Cognitive status prior to the stroke/TIA was assessed using the informant questionnaire on cognitive decline in the elderly (IQCODE). AF was diagnosed according to a standardised procedure that included the documented medical history, ECG upon admission, 24-h Holter-ECG, continuos ECG monitoring, and was categorized into paroxysmal and persistent. Logistic regression analysis was used to evaluate association of AF and prestroke cognitive impairment. A total of 788 patients were enrolled in our study. Of these, 548 (69.5 %) had an IS, TIA was present in 168 (21.3 %) and ICH in 72 (9.1 %) patients. Mean IQCODE was 3.1 (SD 0.4). Prestroke cognitive impairment (IQCODE ≥3.44) was detected in 96 (12.5 %) patients. Of these, 33 patients (4.3 %) were demented before the actual stroke event. AF was independently associated with prestroke cognitive impairment. Patients with an acute stroke frequently show a history of cognitive impairment before the event. AF is independently associated with prestroke cognitive impairment.

AB - Dementia and atrial fibrillation (AF) are common comorbidities in stroke patients. The potential role of AF in cognitive impairment prior to a first stroke has yet not been characterized. The aim of our study was to evaluate the prevalence of prestroke cognitive impairment in stroke patients, and to identify whether AF is associated with prestroke cognitive impairment. In this prospective, single-center, explorative, observational study, consecutive patients with first ever transient ischemic attack (TIA), ischemic (IS) or hemorrhagic stroke (ICH) were included. For each patient cardiovascular risk factors and the National Institutes of Health Stroke Scale were recorded. Cognitive status prior to the stroke/TIA was assessed using the informant questionnaire on cognitive decline in the elderly (IQCODE). AF was diagnosed according to a standardised procedure that included the documented medical history, ECG upon admission, 24-h Holter-ECG, continuos ECG monitoring, and was categorized into paroxysmal and persistent. Logistic regression analysis was used to evaluate association of AF and prestroke cognitive impairment. A total of 788 patients were enrolled in our study. Of these, 548 (69.5 %) had an IS, TIA was present in 168 (21.3 %) and ICH in 72 (9.1 %) patients. Mean IQCODE was 3.1 (SD 0.4). Prestroke cognitive impairment (IQCODE ≥3.44) was detected in 96 (12.5 %) patients. Of these, 33 patients (4.3 %) were demented before the actual stroke event. AF was independently associated with prestroke cognitive impairment. Patients with an acute stroke frequently show a history of cognitive impairment before the event. AF is independently associated with prestroke cognitive impairment.

KW - Aged

KW - Atrial Fibrillation

KW - Brain Ischemia

KW - Cognition Disorders

KW - Comorbidity

KW - Female

KW - Humans

KW - Intracranial Hemorrhages

KW - Ischemic Attack, Transient

KW - Male

KW - Middle Aged

KW - Prevalence

KW - Prospective Studies

KW - Risk Factors

KW - Stroke

KW - Journal Article

KW - Observational Study

KW - Research Support, Non-U.S. Gov't

U2 - 10.1007/s00415-013-7233-3

DO - 10.1007/s00415-013-7233-3

M3 - SCORING: Journal article

C2 - 24413641

VL - 261

SP - 546

EP - 553

JO - J NEUROL

JF - J NEUROL

SN - 0340-5354

IS - 3

ER -