Association of hypertension with depression and generalized anxiety symptoms in a large population-based sample of older adults

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Association of hypertension with depression and generalized anxiety symptoms in a large population-based sample of older adults. / Maatouk, Imad; Herzog, Wolfgang; Böhlen, Friederike; Quinzler, Renate; Löwe, Bernd; Saum, Kai-Uwe; Brenner, Hermann; Wild, Beate.

In: J HYPERTENS, Vol. 34, No. 9, 09.2016, p. 1711-20.

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@article{7577aa24da5e46dd9c14feb7548d7e2f,
title = "Association of hypertension with depression and generalized anxiety symptoms in a large population-based sample of older adults",
abstract = "OBJECTIVE: The aim of the study was to assess the association of hypertension and symptoms of depression and generalized anxiety in a large cohort of elderly people.METHODS: Data were derived from the 8-year follow-up (2008-2010) of the epidemiological ESTHER-cohort study. A total of 3124 randomly chosen participants aged 57-84 were visited at their homes by trained study doctors. General practitioner based diagnosis, self-reported status of hypertension, medication, and blood pressure measurement were considered to define the existence of hypertension. Depression and general anxiety severity were assessed using validated questionnaires. Logistic regression analyses were performed to determine cross-sectional associations between hypertension and clinically significant symptoms of depression (CSD) and generalized anxiety. Well known lifestyle risk factors for hypertension such as obesity were included in multivariate cross-sectional analyses.RESULTS: Hypertension was prevalent in 1659 participants [53.1%; 95% confidence interval (CI) = (51.3; 54.9)]. CSD was detected in 163 participants [5.2%; 95%-CI = (4.4; 6.0)]. Symptoms of generalized anxiety were found in 434 participants [13.9%; 95%-CI = (12.7; 15.1)]. Patients with CSD showed significantly higher odds of being hypertensive [odds ratio (OR) = 1.76; 95%-CI = (1.14; 2.74)]. Participants with symptoms of generalized anxiety were found to have no higher odds for a hypertension diagnosis [OR = 1.1; 95%-CI = (0.85; 1.44)]. Overweight [OR = 1.86; 95%-CI = (1.53; 2.25)] as well as obesity [OR = 3.58; 95%-CI = (2.84; 4.52)] was significantly associated with hypertension.CONCLUSION: CSD appear to be related to hypertension in elderly adults. No association was found between symptoms of generalized anxiety and hypertension.",
keywords = "Journal Article",
author = "Imad Maatouk and Wolfgang Herzog and Friederike B{\"o}hlen and Renate Quinzler and Bernd L{\"o}we and Kai-Uwe Saum and Hermann Brenner and Beate Wild",
year = "2016",
month = sep,
doi = "10.1097/HJH.0000000000001006",
language = "English",
volume = "34",
pages = "1711--20",
journal = "J HYPERTENS",
issn = "0263-6352",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

RIS

TY - JOUR

T1 - Association of hypertension with depression and generalized anxiety symptoms in a large population-based sample of older adults

AU - Maatouk, Imad

AU - Herzog, Wolfgang

AU - Böhlen, Friederike

AU - Quinzler, Renate

AU - Löwe, Bernd

AU - Saum, Kai-Uwe

AU - Brenner, Hermann

AU - Wild, Beate

PY - 2016/9

Y1 - 2016/9

N2 - OBJECTIVE: The aim of the study was to assess the association of hypertension and symptoms of depression and generalized anxiety in a large cohort of elderly people.METHODS: Data were derived from the 8-year follow-up (2008-2010) of the epidemiological ESTHER-cohort study. A total of 3124 randomly chosen participants aged 57-84 were visited at their homes by trained study doctors. General practitioner based diagnosis, self-reported status of hypertension, medication, and blood pressure measurement were considered to define the existence of hypertension. Depression and general anxiety severity were assessed using validated questionnaires. Logistic regression analyses were performed to determine cross-sectional associations between hypertension and clinically significant symptoms of depression (CSD) and generalized anxiety. Well known lifestyle risk factors for hypertension such as obesity were included in multivariate cross-sectional analyses.RESULTS: Hypertension was prevalent in 1659 participants [53.1%; 95% confidence interval (CI) = (51.3; 54.9)]. CSD was detected in 163 participants [5.2%; 95%-CI = (4.4; 6.0)]. Symptoms of generalized anxiety were found in 434 participants [13.9%; 95%-CI = (12.7; 15.1)]. Patients with CSD showed significantly higher odds of being hypertensive [odds ratio (OR) = 1.76; 95%-CI = (1.14; 2.74)]. Participants with symptoms of generalized anxiety were found to have no higher odds for a hypertension diagnosis [OR = 1.1; 95%-CI = (0.85; 1.44)]. Overweight [OR = 1.86; 95%-CI = (1.53; 2.25)] as well as obesity [OR = 3.58; 95%-CI = (2.84; 4.52)] was significantly associated with hypertension.CONCLUSION: CSD appear to be related to hypertension in elderly adults. No association was found between symptoms of generalized anxiety and hypertension.

AB - OBJECTIVE: The aim of the study was to assess the association of hypertension and symptoms of depression and generalized anxiety in a large cohort of elderly people.METHODS: Data were derived from the 8-year follow-up (2008-2010) of the epidemiological ESTHER-cohort study. A total of 3124 randomly chosen participants aged 57-84 were visited at their homes by trained study doctors. General practitioner based diagnosis, self-reported status of hypertension, medication, and blood pressure measurement were considered to define the existence of hypertension. Depression and general anxiety severity were assessed using validated questionnaires. Logistic regression analyses were performed to determine cross-sectional associations between hypertension and clinically significant symptoms of depression (CSD) and generalized anxiety. Well known lifestyle risk factors for hypertension such as obesity were included in multivariate cross-sectional analyses.RESULTS: Hypertension was prevalent in 1659 participants [53.1%; 95% confidence interval (CI) = (51.3; 54.9)]. CSD was detected in 163 participants [5.2%; 95%-CI = (4.4; 6.0)]. Symptoms of generalized anxiety were found in 434 participants [13.9%; 95%-CI = (12.7; 15.1)]. Patients with CSD showed significantly higher odds of being hypertensive [odds ratio (OR) = 1.76; 95%-CI = (1.14; 2.74)]. Participants with symptoms of generalized anxiety were found to have no higher odds for a hypertension diagnosis [OR = 1.1; 95%-CI = (0.85; 1.44)]. Overweight [OR = 1.86; 95%-CI = (1.53; 2.25)] as well as obesity [OR = 3.58; 95%-CI = (2.84; 4.52)] was significantly associated with hypertension.CONCLUSION: CSD appear to be related to hypertension in elderly adults. No association was found between symptoms of generalized anxiety and hypertension.

KW - Journal Article

U2 - 10.1097/HJH.0000000000001006

DO - 10.1097/HJH.0000000000001006

M3 - SCORING: Journal article

C2 - 27341438

VL - 34

SP - 1711

EP - 1720

JO - J HYPERTENS

JF - J HYPERTENS

SN - 0263-6352

IS - 9

ER -