Association of a healthy lifestyle with mortality in older people

TY - JOUR

T1 - Association of a healthy lifestyle with mortality in older people

AU - Robb, Catherine

AU - Carr, Prudence R

AU - Ball, Jocasta

AU - Owen, Alice

AU - Beilin, Lawrence J

AU - Newman, Anne B

AU - Nelson, Mark R

AU - Reid, Christopher M

AU - Orchard, Suzanne G

AU - Neumann, Johannes T

AU - Tonkin, Andrew M

AU - Wolfe, Rory

AU - McNeil, John J

N1 - © 2023. BioMed Central Ltd., part of Springer Nature.

PY - 2023/10/11

Y1 - 2023/10/11

N2 - BACKGROUND: Unhealthy lifestyle behaviours such as smoking, high alcohol consumption, poor diet or low physical activity are associated with morbidity and mortality. Public health guidelines provide recommendations for adherence to these four factors, however, their relationship to the health of older people is less certain.METHODS: The study involved 11,340 Australian participants (median age 7.39 [Interquartile Range (IQR) 71.7, 77.3]) from the ASPirin in Reducing Events in the Elderly study, followed for a median of 6.8 years (IQR: 5.7, 7.9). We investigated whether a point-based lifestyle score based on adherence to guidelines for a healthy diet, physical activity, non-smoking and moderate alcohol consumption was associated with subsequent all-cause and cause-specific mortality.RESULTS: In multivariable adjusted models, compared to those in the unfavourable lifestyle group, individuals in the moderate lifestyle group (Hazard Ratio (HR) 0.73 [95% CI 0.61, 0.88]) and favourable lifestyle group (HR 0.68 [95% CI 0.56, 0.83]) had lower risk of all-cause mortality. A similar pattern was observed for cardiovascular related mortality and non-cancer/non-cardiovascular related mortality. There was no association of lifestyle with cancer-related mortality.CONCLUSIONS: In a large cohort of initially healthy older people, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.

AB - BACKGROUND: Unhealthy lifestyle behaviours such as smoking, high alcohol consumption, poor diet or low physical activity are associated with morbidity and mortality. Public health guidelines provide recommendations for adherence to these four factors, however, their relationship to the health of older people is less certain.METHODS: The study involved 11,340 Australian participants (median age 7.39 [Interquartile Range (IQR) 71.7, 77.3]) from the ASPirin in Reducing Events in the Elderly study, followed for a median of 6.8 years (IQR: 5.7, 7.9). We investigated whether a point-based lifestyle score based on adherence to guidelines for a healthy diet, physical activity, non-smoking and moderate alcohol consumption was associated with subsequent all-cause and cause-specific mortality.RESULTS: In multivariable adjusted models, compared to those in the unfavourable lifestyle group, individuals in the moderate lifestyle group (Hazard Ratio (HR) 0.73 [95% CI 0.61, 0.88]) and favourable lifestyle group (HR 0.68 [95% CI 0.56, 0.83]) had lower risk of all-cause mortality. A similar pattern was observed for cardiovascular related mortality and non-cancer/non-cardiovascular related mortality. There was no association of lifestyle with cancer-related mortality.CONCLUSIONS: In a large cohort of initially healthy older people, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.

KW - Aged

KW - Humans

KW - Australia/epidemiology

KW - Cardiovascular Diseases/epidemiology

KW - Health Behavior

KW - Healthy Lifestyle

KW - Life Style

KW - Prospective Studies

KW - Risk Factors

KW - Diet, Healthy/mortality

KW - Exercise/statistics & numerical data

KW - Alcohol Drinking/epidemiology

KW - Smoking/epidemiology

KW - Mortality

KW - Neoplasms/epidemiology

U2 - 10.1186/s12877-023-04247-9

DO - 10.1186/s12877-023-04247-9

M3 - SCORING: Journal article

C2 - 37821846

VL - 23

SP - 646

JO - BMC GERIATR

JF - BMC GERIATR

SN - 1471-2318

IS - 1

ER -