Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines
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Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines. / Janovic, Aleksa; Milovanovic, Petar; Hahn, Michael; Rakocevic, Zoran; Amling, Michael; Busse, Bjoern; Dimitrijevic, Milovan; Djuric, Marija.
In: DENT TRAUMATOL, Vol. 33, No. 4, 08.2017, p. 300-306.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Association between regional heterogeneity in the mid-facial bone micro-architecture and increased fragility along Le Fort lines
AU - Janovic, Aleksa
AU - Milovanovic, Petar
AU - Hahn, Michael
AU - Rakocevic, Zoran
AU - Amling, Michael
AU - Busse, Bjoern
AU - Dimitrijevic, Milovan
AU - Djuric, Marija
N1 - © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2017/8
Y1 - 2017/8
N2 - BACKGROUND/AIM: Le Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites.MATERIALS AND METHODS: Twenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton.RESULTS: Cortical bone along Le Fort lines showed tendencies toward lower thickness (1.5±0.63 vs 1.75±0.79; P=.39) and greater porosity (11.48±5.67 vs 10.28±5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14±0.69 vs 1.58±0.34; P=.02).CONCLUSIONS: Regional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.
AB - BACKGROUND/AIM: Le Fort lines have traditionally been considered as zones of weakness in the mid-facial skeleton although the structural basis of increased bone fragility at these sites has not yet been investigated. Considering recent findings of occlusal loading-related regional heterogeneity in the mid-facial bone micro-architecture, the aim of this study was to explore whether such heterogeneity in cortical and cancellous bone micro-architecture may contribute to increased fragility at Le Fort fracture sites.MATERIALS AND METHODS: Twenty-five cortical and thirteen cancellous bone specimens were harvested from a dry skull and analyzed by micro-CT. Specimens were classified into Le Fort or Non-Le Fort groups based on their location in the mid-facial skeleton.RESULTS: Cortical bone along Le Fort lines showed tendencies toward lower thickness (1.5±0.63 vs 1.75±0.79; P=.39) and greater porosity (11.48±5.67 vs 10.28±5.28; P=.59). A significant difference was detected in the trabecular degree of anisotropy which was higher in cancellous bone from Le Fort fracture sites (2.14±0.69 vs 1.58±0.34; P=.02).CONCLUSIONS: Regional heterogeneity in cortical bone micro-architecture could not fully explain increased fragility of the mid-facial skeleton at the Le Fort lines. However, regional differences in trabecular bone anisotropy may contribute to increased bone fragility.
KW - Journal Article
U2 - 10.1111/edt.12333
DO - 10.1111/edt.12333
M3 - SCORING: Journal article
C2 - 28258969
VL - 33
SP - 300
EP - 306
JO - DENT TRAUMATOL
JF - DENT TRAUMATOL
SN - 1600-4469
IS - 4
ER -
