Association between pulmonary embolism and COVID-19 disease
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Association between pulmonary embolism and COVID-19 disease. / Stevik, Martin; Zelenak, Kamil; Dzian, Anton; Drobna Saniova, Beata; Trabalkova, Zuzana; Lozan, Daniel; Grendar, Marian; Sykora, Jan; Vorcak, Martin; Malik, Marek; Meyer, Lukas; Fiehler, Jens; Vajdova, Veronika.
In: NEUROENDOCRINOL LETT, Vol. 44, No. 2, 30.04.2023, p. 105-114.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Association between pulmonary embolism and COVID-19 disease
AU - Stevik, Martin
AU - Zelenak, Kamil
AU - Dzian, Anton
AU - Drobna Saniova, Beata
AU - Trabalkova, Zuzana
AU - Lozan, Daniel
AU - Grendar, Marian
AU - Sykora, Jan
AU - Vorcak, Martin
AU - Malik, Marek
AU - Meyer, Lukas
AU - Fiehler, Jens
AU - Vajdova, Veronika
PY - 2023/4/30
Y1 - 2023/4/30
N2 - OBJECTIVES: The current retrospective study focused on evaluation of the relationship between pulmonary embolism during COVID-19 pandemic and demographic, presenting symptoms, comorbidities and laboratory results in patients who underwent CT angiography of the pulmonary arteries.METHODS: The study enrolled all adult patients with suspected acute pulmonary embolism (PE) who underwent computed tomography pulmonary angiography (CTPA) between March 1, 2020, and April 30, 2022, during the SARS-CoV-2 pandemic. 1698 CTPAs were reviewed and various data were collected. Based on examination results, patients were divided into 4 groups: a group with positive PE and a group with negative PE for both COVID-19 and non-COVID-19 patients.RESULTS: When comparing different predictors of COVID-19 patients and non-COVID-19 patients we noticed lower probability of PE in female gender (OR 0.77, 95% CI: 0.60-1.00, p = 0.052) and in chronic obstructive pulmonary disease (COPD) patients (OR 0.6, 95% CI: 0.38-0.90, p = 0.017). Higher probability of PE was in cases of older age (OR 1.02, 95% CI: 1.01-1.02, p < 0.001), increased heart rate (OR 1.01, 95% CI: 1.01-1.02, p < 0.001) and increased D-dimer levels (OR 1.03, 95% CI: 1.02-1.04, p < 0.001).CONCLUSION: Considering predictors of PE there was a significantly lower risk of PE in the female gender and COPD, and a higher risk with increasing age, heart rate, and D-dimer levels.
AB - OBJECTIVES: The current retrospective study focused on evaluation of the relationship between pulmonary embolism during COVID-19 pandemic and demographic, presenting symptoms, comorbidities and laboratory results in patients who underwent CT angiography of the pulmonary arteries.METHODS: The study enrolled all adult patients with suspected acute pulmonary embolism (PE) who underwent computed tomography pulmonary angiography (CTPA) between March 1, 2020, and April 30, 2022, during the SARS-CoV-2 pandemic. 1698 CTPAs were reviewed and various data were collected. Based on examination results, patients were divided into 4 groups: a group with positive PE and a group with negative PE for both COVID-19 and non-COVID-19 patients.RESULTS: When comparing different predictors of COVID-19 patients and non-COVID-19 patients we noticed lower probability of PE in female gender (OR 0.77, 95% CI: 0.60-1.00, p = 0.052) and in chronic obstructive pulmonary disease (COPD) patients (OR 0.6, 95% CI: 0.38-0.90, p = 0.017). Higher probability of PE was in cases of older age (OR 1.02, 95% CI: 1.01-1.02, p < 0.001), increased heart rate (OR 1.01, 95% CI: 1.01-1.02, p < 0.001) and increased D-dimer levels (OR 1.03, 95% CI: 1.02-1.04, p < 0.001).CONCLUSION: Considering predictors of PE there was a significantly lower risk of PE in the female gender and COPD, and a higher risk with increasing age, heart rate, and D-dimer levels.
KW - Adult
KW - Humans
KW - Female
KW - COVID-19/complications
KW - SARS-CoV-2
KW - Retrospective Studies
KW - Pandemics
KW - Pulmonary Embolism/diagnostic imaging
KW - Pulmonary Disease, Chronic Obstructive
M3 - SCORING: Journal article
C2 - 37182233
VL - 44
SP - 105
EP - 114
JO - NEUROENDOCRINOL LETT
JF - NEUROENDOCRINOL LETT
SN - 0172-780X
IS - 2
ER -