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Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010

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Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010. / Sun, Jiangling; Wang, Wang; Li, Dongdong; Song, Jukun; Chen, Zhu; Chen, Liming; Smeets, Ralf; Beikler, Thomas; Strenge, Jan; Yang, Zhe; Friedrich, Reinhard E.

In: BMC ORAL HEALTH, Vol. 23, No. 1, 22.07.2023, p. 512.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Sun, J, Wang, W, Li, D, Song, J, Chen, Z, Chen, L, Smeets, R, Beikler, T, Strenge, J, Yang, Z & Friedrich, RE 2023, 'Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010', BMC ORAL HEALTH, vol. 23, no. 1, pp. 512. https://doi.org/10.1186/s12903-023-03189-3

APA

Sun, J., Wang, W., Li, D., Song, J., Chen, Z., Chen, L., Smeets, R., Beikler, T., Strenge, J., Yang, Z., & Friedrich, R. E. (2023). Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010. BMC ORAL HEALTH, 23(1), 512. https://doi.org/10.1186/s12903-023-03189-3

Vancouver

Sun J, Wang W, Li D, Song J, Chen Z, Chen L et al. Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010. BMC ORAL HEALTH. 2023 Jul 22;23(1):512. https://doi.org/10.1186/s12903-023-03189-3

Bibtex

@article{fe40161bf8f548b7a0369c80cbb32a69,
title = "Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010",
abstract = "BACKGROUND: Various data have been obtained on the relationship between body mass index (BMI) and C-reactive protein (CRP) and periodontitis. The aim of this study was to determine whether CRP/BMI are associated with periodontitis using data from the National Health and Nutrition Examination Survey (NHANES) database.METHODS: A cross-sectional analysis of data from 3602 participants in the 2009-2010 NHANES cycle was performed. The definition of periodontitis was used to divide participants into four groups according to the criteria of Eke. Correlations between CRP/BMI and periodontitis were tested for statistical significance by means of descriptive statistics, multivariate regression, and subgroup-stratified analyses, with and without adjustments for confounders (such as age and sex).RESULTS: There were no statistically significant differences (p > 0.05) regarding BMI and the development of periodontitis. After adjustment for age, sex, race, marital status, annual family income, alcohol consumption, hypertension, smoking, chronic pulmonary disease, cardiovascular disease, diabetes, flossing, and arthritis, CRP correlated significantly with the development of periodontitis in the subgroups stratified by obesity, with an odds ratio (OR) of 1.2 (95% CI, 1.0 to 1.5).CONCLUSION: Through data analysis, we found an association between CRP levels and periodontitis prevalence in the American population, although this association was only present in the obese population. While there are several hypotheses about the underlying mechanism, further studies are needed to validate these findings.",
keywords = "Humans, C-Reactive Protein, Cross-Sectional Studies, Nutrition Surveys, Obesity/complications, Periodontitis/epidemiology",
author = "Jiangling Sun and Wang Wang and Dongdong Li and Jukun Song and Zhu Chen and Liming Chen and Ralf Smeets and Thomas Beikler and Jan Strenge and Zhe Yang and Friedrich, {Reinhard E}",
note = "{\textcopyright} 2023. The Author(s).",
year = "2023",
month = jul,
day = "22",
doi = "10.1186/s12903-023-03189-3",
language = "English",
volume = "23",
pages = "512",
journal = "BMC ORAL HEALTH",
issn = "1472-6831",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Association between C-Reactive protein and periodontitis in an obese population from the NHANES 2009-2010

AU - Sun, Jiangling

AU - Wang, Wang

AU - Li, Dongdong

AU - Song, Jukun

AU - Chen, Zhu

AU - Chen, Liming

AU - Smeets, Ralf

AU - Beikler, Thomas

AU - Strenge, Jan

AU - Yang, Zhe

AU - Friedrich, Reinhard E

N1 - © 2023. The Author(s).

PY - 2023/7/22

Y1 - 2023/7/22

N2 - BACKGROUND: Various data have been obtained on the relationship between body mass index (BMI) and C-reactive protein (CRP) and periodontitis. The aim of this study was to determine whether CRP/BMI are associated with periodontitis using data from the National Health and Nutrition Examination Survey (NHANES) database.METHODS: A cross-sectional analysis of data from 3602 participants in the 2009-2010 NHANES cycle was performed. The definition of periodontitis was used to divide participants into four groups according to the criteria of Eke. Correlations between CRP/BMI and periodontitis were tested for statistical significance by means of descriptive statistics, multivariate regression, and subgroup-stratified analyses, with and without adjustments for confounders (such as age and sex).RESULTS: There were no statistically significant differences (p > 0.05) regarding BMI and the development of periodontitis. After adjustment for age, sex, race, marital status, annual family income, alcohol consumption, hypertension, smoking, chronic pulmonary disease, cardiovascular disease, diabetes, flossing, and arthritis, CRP correlated significantly with the development of periodontitis in the subgroups stratified by obesity, with an odds ratio (OR) of 1.2 (95% CI, 1.0 to 1.5).CONCLUSION: Through data analysis, we found an association between CRP levels and periodontitis prevalence in the American population, although this association was only present in the obese population. While there are several hypotheses about the underlying mechanism, further studies are needed to validate these findings.

AB - BACKGROUND: Various data have been obtained on the relationship between body mass index (BMI) and C-reactive protein (CRP) and periodontitis. The aim of this study was to determine whether CRP/BMI are associated with periodontitis using data from the National Health and Nutrition Examination Survey (NHANES) database.METHODS: A cross-sectional analysis of data from 3602 participants in the 2009-2010 NHANES cycle was performed. The definition of periodontitis was used to divide participants into four groups according to the criteria of Eke. Correlations between CRP/BMI and periodontitis were tested for statistical significance by means of descriptive statistics, multivariate regression, and subgroup-stratified analyses, with and without adjustments for confounders (such as age and sex).RESULTS: There were no statistically significant differences (p > 0.05) regarding BMI and the development of periodontitis. After adjustment for age, sex, race, marital status, annual family income, alcohol consumption, hypertension, smoking, chronic pulmonary disease, cardiovascular disease, diabetes, flossing, and arthritis, CRP correlated significantly with the development of periodontitis in the subgroups stratified by obesity, with an odds ratio (OR) of 1.2 (95% CI, 1.0 to 1.5).CONCLUSION: Through data analysis, we found an association between CRP levels and periodontitis prevalence in the American population, although this association was only present in the obese population. While there are several hypotheses about the underlying mechanism, further studies are needed to validate these findings.

KW - Humans

KW - C-Reactive Protein

KW - Cross-Sectional Studies

KW - Nutrition Surveys

KW - Obesity/complications

KW - Periodontitis/epidemiology

U2 - 10.1186/s12903-023-03189-3

DO - 10.1186/s12903-023-03189-3

M3 - SCORING: Journal article

C2 - 37481511

VL - 23

SP - 512

JO - BMC ORAL HEALTH

JF - BMC ORAL HEALTH

SN - 1472-6831

IS - 1

ER -