Are metastases from metastases clinical relevant? Computer modelling of cancer spread in a case of hepatocellular carcinoma.
Standard
Are metastases from metastases clinical relevant? Computer modelling of cancer spread in a case of hepatocellular carcinoma. / Bethge, Anja; Schumacher, Udo; Wree, Andreas; Wedemann, Gero.
In: PLOS ONE, Vol. 7, No. 4, 4, 2012, p. 35689.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Are metastases from metastases clinical relevant? Computer modelling of cancer spread in a case of hepatocellular carcinoma.
AU - Bethge, Anja
AU - Schumacher, Udo
AU - Wree, Andreas
AU - Wedemann, Gero
PY - 2012
Y1 - 2012
N2 - Metastasis formation remains an enigmatic process and one of the main questions recently asked is whether metastases are able to generate further metastases. Different models have been proposed to answer this question; however, their clinical significance remains unclear. Therefore a computer model was developed that permits comparison of the different models quantitatively with clinical data and that additionally predicts the outcome of treatment interventions.
AB - Metastasis formation remains an enigmatic process and one of the main questions recently asked is whether metastases are able to generate further metastases. Different models have been proposed to answer this question; however, their clinical significance remains unclear. Therefore a computer model was developed that permits comparison of the different models quantitatively with clinical data and that additionally predicts the outcome of treatment interventions.
KW - Humans
KW - Cell Count
KW - Computer Simulation
KW - Carcinoma, Hepatocellular/mortality/pathology
KW - Liver Neoplasms/mortality/pathology
KW - Neoplasm Metastasis
KW - Neoplastic Stem Cells/cytology
KW - Humans
KW - Cell Count
KW - Computer Simulation
KW - Carcinoma, Hepatocellular/mortality/pathology
KW - Liver Neoplasms/mortality/pathology
KW - Neoplasm Metastasis
KW - Neoplastic Stem Cells/cytology
U2 - 10.1371/journal.pone.0035689
DO - 10.1371/journal.pone.0035689
M3 - SCORING: Journal article
VL - 7
SP - 35689
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 4
M1 - 4
ER -