Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV.
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Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV. / Stieler, Kristin; Fischer, Nicole.
In: PLOS ONE, Vol. 5, No. 7, 7, 2010, p. 11738.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Apobec 3G efficiently reduces infectivity of the human exogenous gammaretrovirus XMRV.
AU - Stieler, Kristin
AU - Fischer, Nicole
PY - 2010
Y1 - 2010
N2 - The human exogenous gammaretrovirus XMRV is thought to be implicated in prostate cancer and chronic fatigue syndrome. Besides pressing epidemiologic questions, the elucidation of the tissue and cell tropism of the virus, as well as its sensitivity to retroviral restriction factors is of fundamental importance. The Apobec3 (A3) proteins, a family of cytidine deaminases, are one important group of host proteins that control primary infection and efficient viral spread.
AB - The human exogenous gammaretrovirus XMRV is thought to be implicated in prostate cancer and chronic fatigue syndrome. Besides pressing epidemiologic questions, the elucidation of the tissue and cell tropism of the virus, as well as its sensitivity to retroviral restriction factors is of fundamental importance. The Apobec3 (A3) proteins, a family of cytidine deaminases, are one important group of host proteins that control primary infection and efficient viral spread.
U2 - 10.1371/journal.pone.0011738
DO - 10.1371/journal.pone.0011738
M3 - SCORING: Zeitschriftenaufsatz
VL - 5
SP - 11738
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 7
M1 - 7
ER -