Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis
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Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis. / Eggers, C; Hagel, C; Pfeiffer, G.
In: J NEUROL SCI, Vol. 155, No. 2, 05.03.1998, p. 178-81.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Anti-Hu-associated paraneoplastic sensory neuropathy with peripheral nerve demyelination and microvasculitis
AU - Eggers, C
AU - Hagel, C
AU - Pfeiffer, G
PY - 1998/3/5
Y1 - 1998/3/5
N2 - A patient had a paraneoplastic autonomic, then sensory, then sensory-motor neuropathy with small cell lung carcinoma and a high titer Anti-Hu antibody to nuclei of neuronal cells. As an unusual finding there was electrophysiological and pathological evidence of demyelination and a peripheral nerve microvasculitis. The relationship of microvasculitis and peripheral nerve demyelination is discussed and their occurrence with paraneoplastic anti-Hu-associated sensory neuropathy is suggested not to be by chance.
AB - A patient had a paraneoplastic autonomic, then sensory, then sensory-motor neuropathy with small cell lung carcinoma and a high titer Anti-Hu antibody to nuclei of neuronal cells. As an unusual finding there was electrophysiological and pathological evidence of demyelination and a peripheral nerve microvasculitis. The relationship of microvasculitis and peripheral nerve demyelination is discussed and their occurrence with paraneoplastic anti-Hu-associated sensory neuropathy is suggested not to be by chance.
KW - Aged
KW - Antibodies
KW - Biopsy
KW - Carcinoma, Small Cell
KW - Demyelinating Diseases
KW - Electromyography
KW - Hereditary Sensory and Autonomic Neuropathies
KW - Hu Paraneoplastic Encephalomyelitis Antigens
KW - Humans
KW - Lung Neoplasms
KW - Male
KW - Nerve Tissue Proteins
KW - Neural Conduction
KW - Paraneoplastic Syndromes
KW - Peripheral Nerves
KW - RNA-Binding Proteins
KW - Vasculitis
M3 - SCORING: Journal article
C2 - 9562263
VL - 155
SP - 178
EP - 181
JO - J NEUROL SCI
JF - J NEUROL SCI
SN - 0022-510X
IS - 2
ER -