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Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses

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Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses. / Pischke, S; Knoop, E V; Mader, M; Kling, L; Wolski, A; Wagner, A; Mueller, K; Horvatits, T; Stiller, J; Wisnewski, K; Kohn, B; Schulze Zur Wiesch, J; Groschup, M H; Eiden, M.

In: SCI REP-UK, Vol. 13, No. 1, 07.11.2023, p. 19240.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Pischke, S, Knoop, EV, Mader, M, Kling, L, Wolski, A, Wagner, A, Mueller, K, Horvatits, T, Stiller, J, Wisnewski, K, Kohn, B, Schulze Zur Wiesch, J, Groschup, MH & Eiden, M 2023, 'Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses', SCI REP-UK, vol. 13, no. 1, pp. 19240. https://doi.org/10.1038/s41598-023-46009-y

APA

Pischke, S., Knoop, E. V., Mader, M., Kling, L., Wolski, A., Wagner, A., Mueller, K., Horvatits, T., Stiller, J., Wisnewski, K., Kohn, B., Schulze Zur Wiesch, J., Groschup, M. H., & Eiden, M. (2023). Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses. SCI REP-UK, 13(1), 19240. https://doi.org/10.1038/s41598-023-46009-y

Vancouver

Pischke S, Knoop EV, Mader M, Kling L, Wolski A, Wagner A et al. Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses. SCI REP-UK. 2023 Nov 7;13(1):19240. https://doi.org/10.1038/s41598-023-46009-y

Bibtex

@article{083b32a49d34438e8a4b3b2cc2fd9aac,
title = "Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses",
abstract = "Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as possible sources of HEV transmission in Germany still needs to be defined. A monitoring study was therefore carried out on dogs, cats, and horses from Germany. In total 365 serum samples from pets (124 dogs, 119 cats, and 122 horses) were tested for HEV by PCR and for anti-HEV antibodies by a commercial ELISA. The HEV seroprevalence determined by the sero-assay varied significantly between dogs (10%), cats (6%), and horses (2%). Liver injury-related enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) showed no differences between HEV-positive or negative animals. None of the pet serum samples tested positive for PCR. This serological study suggests that dogs and cats are significantly exposed to HEV in Germany, while horses are of minor relevance.",
keywords = "Animals, Cats, Dogs, Cat Diseases, Dog Diseases/epidemiology, Hepatitis E/epidemiology, Hepatitis E virus, Horses, Seroepidemiologic Studies, Viremia",
author = "S Pischke and Knoop, {E V} and M Mader and L Kling and A Wolski and A Wagner and K Mueller and T Horvatits and J Stiller and K Wisnewski and B Kohn and {Schulze Zur Wiesch}, J and Groschup, {M H} and M Eiden",
note = "{\textcopyright} 2023. The Author(s).",
year = "2023",
month = nov,
day = "7",
doi = "10.1038/s41598-023-46009-y",
language = "English",
volume = "13",
pages = "19240",
journal = "SCI REP-UK",
issn = "2045-2322",
publisher = "NATURE PUBLISHING GROUP",
number = "1",

}

RIS

TY - JOUR

T1 - Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses

AU - Pischke, S

AU - Knoop, E V

AU - Mader, M

AU - Kling, L

AU - Wolski, A

AU - Wagner, A

AU - Mueller, K

AU - Horvatits, T

AU - Stiller, J

AU - Wisnewski, K

AU - Kohn, B

AU - Schulze Zur Wiesch, J

AU - Groschup, M H

AU - Eiden, M

N1 - © 2023. The Author(s).

PY - 2023/11/7

Y1 - 2023/11/7

N2 - Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as possible sources of HEV transmission in Germany still needs to be defined. A monitoring study was therefore carried out on dogs, cats, and horses from Germany. In total 365 serum samples from pets (124 dogs, 119 cats, and 122 horses) were tested for HEV by PCR and for anti-HEV antibodies by a commercial ELISA. The HEV seroprevalence determined by the sero-assay varied significantly between dogs (10%), cats (6%), and horses (2%). Liver injury-related enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) showed no differences between HEV-positive or negative animals. None of the pet serum samples tested positive for PCR. This serological study suggests that dogs and cats are significantly exposed to HEV in Germany, while horses are of minor relevance.

AB - Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as possible sources of HEV transmission in Germany still needs to be defined. A monitoring study was therefore carried out on dogs, cats, and horses from Germany. In total 365 serum samples from pets (124 dogs, 119 cats, and 122 horses) were tested for HEV by PCR and for anti-HEV antibodies by a commercial ELISA. The HEV seroprevalence determined by the sero-assay varied significantly between dogs (10%), cats (6%), and horses (2%). Liver injury-related enzymes, alanine transaminase (ALT), and aspartate transaminase (AST) showed no differences between HEV-positive or negative animals. None of the pet serum samples tested positive for PCR. This serological study suggests that dogs and cats are significantly exposed to HEV in Germany, while horses are of minor relevance.

KW - Animals

KW - Cats

KW - Dogs

KW - Cat Diseases

KW - Dog Diseases/epidemiology

KW - Hepatitis E/epidemiology

KW - Hepatitis E virus

KW - Horses

KW - Seroepidemiologic Studies

KW - Viremia

U2 - 10.1038/s41598-023-46009-y

DO - 10.1038/s41598-023-46009-y

M3 - SCORING: Journal article

C2 - 37935733

VL - 13

SP - 19240

JO - SCI REP-UK

JF - SCI REP-UK

SN - 2045-2322

IS - 1

ER -