Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study

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Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study. / Wipper, Sabine; Lohrenz, Christina; Ahlbrecht, Oliver; Diener, Holger; Carpenter, Sebastian W; Detter, Christian; Larena-Avellaneda, Axel; Debus, Eike Sebastian; Kölbel, Tilo.

In: J ENDOVASC THER, Vol. 20, No. 2, 04.2013, p. 233-241.

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@article{2e2524c369e24682a722296f14624979,
title = "Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study",
abstract = "PURPOSE: To describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft.METHODS: Six domestic pigs were operated with retrograde delivery of a single side branch arch endograft and antegrade introduction of a mating stent-graft using transseptal access (n=3) and transapical access (n=3). Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied.RESULTS: Transseptal and transapical access techniques were feasible in all animals. Catheterization and introduction of the mating stent-graft was feasible in 2 of 3 animals in the transseptal group and all animals in the transapical group. Technical feasibility was better in the transapical group, with shorter operating and fluoroscopy times and less hemodynamic impact during endograft deployment. Hemodynamic changes were short and reversible in all animals in both groups.CONCLUSION: Antegrade transcardiac access to the aortic arch for implantation of mating stent-grafts in branched arch endografting is feasible in a porcine model with reversible impact on hemodynamic measures during deployment. Transapical access was technically easier, with shorter operating and fluoroscopy times.",
keywords = "Animals, Aorta, Thoracic/diagnostic imaging, Aortography/methods, Blood Vessel Prosthesis, Blood Vessel Prosthesis Implantation/instrumentation, Endovascular Procedures/instrumentation, Feasibility Studies, Female, Fluoroscopy, Hemodynamics, Male, Models, Animal, Prosthesis Design, Radiography, Interventional/methods, Stents, Sus scrofa, Time Factors, Tomography, X-Ray Computed",
author = "Sabine Wipper and Christina Lohrenz and Oliver Ahlbrecht and Holger Diener and Carpenter, {Sebastian W} and Christian Detter and Axel Larena-Avellaneda and Debus, {Eike Sebastian} and Tilo K{\"o}lbel",
year = "2013",
month = apr,
doi = "10.1583/1545-1550-20.2.233",
language = "English",
volume = "20",
pages = "233--241",
journal = "J ENDOVASC THER",
issn = "1526-6028",
publisher = "International Society of Endovascular Specialists",
number = "2",

}

RIS

TY - JOUR

T1 - Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study

AU - Wipper, Sabine

AU - Lohrenz, Christina

AU - Ahlbrecht, Oliver

AU - Diener, Holger

AU - Carpenter, Sebastian W

AU - Detter, Christian

AU - Larena-Avellaneda, Axel

AU - Debus, Eike Sebastian

AU - Kölbel, Tilo

PY - 2013/4

Y1 - 2013/4

N2 - PURPOSE: To describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft.METHODS: Six domestic pigs were operated with retrograde delivery of a single side branch arch endograft and antegrade introduction of a mating stent-graft using transseptal access (n=3) and transapical access (n=3). Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied.RESULTS: Transseptal and transapical access techniques were feasible in all animals. Catheterization and introduction of the mating stent-graft was feasible in 2 of 3 animals in the transseptal group and all animals in the transapical group. Technical feasibility was better in the transapical group, with shorter operating and fluoroscopy times and less hemodynamic impact during endograft deployment. Hemodynamic changes were short and reversible in all animals in both groups.CONCLUSION: Antegrade transcardiac access to the aortic arch for implantation of mating stent-grafts in branched arch endografting is feasible in a porcine model with reversible impact on hemodynamic measures during deployment. Transapical access was technically easier, with shorter operating and fluoroscopy times.

AB - PURPOSE: To describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft.METHODS: Six domestic pigs were operated with retrograde delivery of a single side branch arch endograft and antegrade introduction of a mating stent-graft using transseptal access (n=3) and transapical access (n=3). Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied.RESULTS: Transseptal and transapical access techniques were feasible in all animals. Catheterization and introduction of the mating stent-graft was feasible in 2 of 3 animals in the transseptal group and all animals in the transapical group. Technical feasibility was better in the transapical group, with shorter operating and fluoroscopy times and less hemodynamic impact during endograft deployment. Hemodynamic changes were short and reversible in all animals in both groups.CONCLUSION: Antegrade transcardiac access to the aortic arch for implantation of mating stent-grafts in branched arch endografting is feasible in a porcine model with reversible impact on hemodynamic measures during deployment. Transapical access was technically easier, with shorter operating and fluoroscopy times.

KW - Animals

KW - Aorta, Thoracic/diagnostic imaging

KW - Aortography/methods

KW - Blood Vessel Prosthesis

KW - Blood Vessel Prosthesis Implantation/instrumentation

KW - Endovascular Procedures/instrumentation

KW - Feasibility Studies

KW - Female

KW - Fluoroscopy

KW - Hemodynamics

KW - Male

KW - Models, Animal

KW - Prosthesis Design

KW - Radiography, Interventional/methods

KW - Stents

KW - Sus scrofa

KW - Time Factors

KW - Tomography, X-Ray Computed

U2 - 10.1583/1545-1550-20.2.233

DO - 10.1583/1545-1550-20.2.233

M3 - SCORING: Journal article

C2 - 23581770

VL - 20

SP - 233

EP - 241

JO - J ENDOVASC THER

JF - J ENDOVASC THER

SN - 1526-6028

IS - 2

ER -