Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study
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Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study. / Wipper, Sabine; Lohrenz, Christina; Ahlbrecht, Oliver; Diener, Holger; Carpenter, Sebastian W; Detter, Christian; Larena-Avellaneda, Axel; Debus, Eike Sebastian; Kölbel, Tilo.
In: J ENDOVASC THER, Vol. 20, No. 2, 04.2013, p. 233-241.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Antegrade side branch access in branched aortic arch endografts: a porcine feasibility study
AU - Wipper, Sabine
AU - Lohrenz, Christina
AU - Ahlbrecht, Oliver
AU - Diener, Holger
AU - Carpenter, Sebastian W
AU - Detter, Christian
AU - Larena-Avellaneda, Axel
AU - Debus, Eike Sebastian
AU - Kölbel, Tilo
PY - 2013/4
Y1 - 2013/4
N2 - PURPOSE: To describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft.METHODS: Six domestic pigs were operated with retrograde delivery of a single side branch arch endograft and antegrade introduction of a mating stent-graft using transseptal access (n=3) and transapical access (n=3). Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied.RESULTS: Transseptal and transapical access techniques were feasible in all animals. Catheterization and introduction of the mating stent-graft was feasible in 2 of 3 animals in the transseptal group and all animals in the transapical group. Technical feasibility was better in the transapical group, with shorter operating and fluoroscopy times and less hemodynamic impact during endograft deployment. Hemodynamic changes were short and reversible in all animals in both groups.CONCLUSION: Antegrade transcardiac access to the aortic arch for implantation of mating stent-grafts in branched arch endografting is feasible in a porcine model with reversible impact on hemodynamic measures during deployment. Transapical access was technically easier, with shorter operating and fluoroscopy times.
AB - PURPOSE: To describe the deployment technique for a single side branch arch endograft in a porcine model and prove the concept of transseptal or transapical antegrade access for catheterization and introduction of the mating stent-graft.METHODS: Six domestic pigs were operated with retrograde delivery of a single side branch arch endograft and antegrade introduction of a mating stent-graft using transseptal access (n=3) and transapical access (n=3). Technical feasibility, operating time, radiation parameters, and hemodynamic changes were studied.RESULTS: Transseptal and transapical access techniques were feasible in all animals. Catheterization and introduction of the mating stent-graft was feasible in 2 of 3 animals in the transseptal group and all animals in the transapical group. Technical feasibility was better in the transapical group, with shorter operating and fluoroscopy times and less hemodynamic impact during endograft deployment. Hemodynamic changes were short and reversible in all animals in both groups.CONCLUSION: Antegrade transcardiac access to the aortic arch for implantation of mating stent-grafts in branched arch endografting is feasible in a porcine model with reversible impact on hemodynamic measures during deployment. Transapical access was technically easier, with shorter operating and fluoroscopy times.
KW - Animals
KW - Aorta, Thoracic/diagnostic imaging
KW - Aortography/methods
KW - Blood Vessel Prosthesis
KW - Blood Vessel Prosthesis Implantation/instrumentation
KW - Endovascular Procedures/instrumentation
KW - Feasibility Studies
KW - Female
KW - Fluoroscopy
KW - Hemodynamics
KW - Male
KW - Models, Animal
KW - Prosthesis Design
KW - Radiography, Interventional/methods
KW - Stents
KW - Sus scrofa
KW - Time Factors
KW - Tomography, X-Ray Computed
U2 - 10.1583/1545-1550-20.2.233
DO - 10.1583/1545-1550-20.2.233
M3 - SCORING: Journal article
C2 - 23581770
VL - 20
SP - 233
EP - 241
JO - J ENDOVASC THER
JF - J ENDOVASC THER
SN - 1526-6028
IS - 2
ER -