Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

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Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas. / Tachezy, Michael; Reichelt, Uta; Melenberg, Tanja; Gebauer, Florian; Izbicki, Jakob R.; Kaifi, Jussuf.

In: HISTOL HISTOPATHOL, Vol. 25, No. 10, 10, 2010, p. 1239-1246.

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@article{f77f34a82e354730b8582e1f96bc00ff,
title = "Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.",
abstract = "Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic factors will help to address this. Angiogenesis plays an elementary role in the development of malignant tumors and may well also be important in the development of IPMN of the pancreas. Therefore we investigated endothelial cell marker CD31 (PECAM-1) and angiogenesis associated marker CD105 (endoglin) by immunohistochemistry.",
keywords = "Adult, Germany, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Immunohistochemistry, Prognosis, Time Factors, Retrospective Studies, Neoplasm Staging, Cell Proliferation, Kaplan-Meier Estimate, Tumor Markers, Biological analysis, Antigens, CD analysis, Antigens, CD31 analysis, Carcinoma, Pancreatic Ductal blood supply, Carcinoma, Papillary blood supply, Ki-67 Antigen analysis, Neoplasm Invasiveness, Neoplasms, Cystic, Mucinous, and Serous blood supply, Neovascularization, Pathologic metabolism, Pancreatic Neoplasms blood supply, Receptors, Cell Surface analysis, Adult, Germany, Humans, Male, Aged, Female, Middle Aged, Aged, 80 and over, Immunohistochemistry, Prognosis, Time Factors, Retrospective Studies, Neoplasm Staging, Cell Proliferation, Kaplan-Meier Estimate, Tumor Markers, Biological analysis, Antigens, CD analysis, Antigens, CD31 analysis, Carcinoma, Pancreatic Ductal blood supply, Carcinoma, Papillary blood supply, Ki-67 Antigen analysis, Neoplasm Invasiveness, Neoplasms, Cystic, Mucinous, and Serous blood supply, Neovascularization, Pathologic metabolism, Pancreatic Neoplasms blood supply, Receptors, Cell Surface analysis",
author = "Michael Tachezy and Uta Reichelt and Tanja Melenberg and Florian Gebauer and Izbicki, {Jakob R.} and Jussuf Kaifi",
year = "2010",
language = "Deutsch",
volume = "25",
pages = "1239--1246",
journal = "HISTOL HISTOPATHOL",
issn = "0213-3911",
publisher = "Histology and Histopathology",
number = "10",

}

RIS

TY - JOUR

T1 - Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

AU - Tachezy, Michael

AU - Reichelt, Uta

AU - Melenberg, Tanja

AU - Gebauer, Florian

AU - Izbicki, Jakob R.

AU - Kaifi, Jussuf

PY - 2010

Y1 - 2010

N2 - Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic factors will help to address this. Angiogenesis plays an elementary role in the development of malignant tumors and may well also be important in the development of IPMN of the pancreas. Therefore we investigated endothelial cell marker CD31 (PECAM-1) and angiogenesis associated marker CD105 (endoglin) by immunohistochemistry.

AB - Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic factors will help to address this. Angiogenesis plays an elementary role in the development of malignant tumors and may well also be important in the development of IPMN of the pancreas. Therefore we investigated endothelial cell marker CD31 (PECAM-1) and angiogenesis associated marker CD105 (endoglin) by immunohistochemistry.

KW - Adult

KW - Germany

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Immunohistochemistry

KW - Prognosis

KW - Time Factors

KW - Retrospective Studies

KW - Neoplasm Staging

KW - Cell Proliferation

KW - Kaplan-Meier Estimate

KW - Tumor Markers, Biological analysis

KW - Antigens, CD analysis

KW - Antigens, CD31 analysis

KW - Carcinoma, Pancreatic Ductal blood supply

KW - Carcinoma, Papillary blood supply

KW - Ki-67 Antigen analysis

KW - Neoplasm Invasiveness

KW - Neoplasms, Cystic, Mucinous, and Serous blood supply

KW - Neovascularization, Pathologic metabolism

KW - Pancreatic Neoplasms blood supply

KW - Receptors, Cell Surface analysis

KW - Adult

KW - Germany

KW - Humans

KW - Male

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Immunohistochemistry

KW - Prognosis

KW - Time Factors

KW - Retrospective Studies

KW - Neoplasm Staging

KW - Cell Proliferation

KW - Kaplan-Meier Estimate

KW - Tumor Markers, Biological analysis

KW - Antigens, CD analysis

KW - Antigens, CD31 analysis

KW - Carcinoma, Pancreatic Ductal blood supply

KW - Carcinoma, Papillary blood supply

KW - Ki-67 Antigen analysis

KW - Neoplasm Invasiveness

KW - Neoplasms, Cystic, Mucinous, and Serous blood supply

KW - Neovascularization, Pathologic metabolism

KW - Pancreatic Neoplasms blood supply

KW - Receptors, Cell Surface analysis

M3 - SCORING: Zeitschriftenaufsatz

VL - 25

SP - 1239

EP - 1246

JO - HISTOL HISTOPATHOL

JF - HISTOL HISTOPATHOL

SN - 0213-3911

IS - 10

M1 - 10

ER -