Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.
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Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas. / Tachezy, Michael; Reichelt, Uta; Melenberg, Tanja; Gebauer, Florian; Izbicki, Jakob R.; Kaifi, Jussuf.
In: HISTOL HISTOPATHOL, Vol. 25, No. 10, 10, 2010, p. 1239-1246.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Angiogenesis index CD105 (endoglin)/CD31 (PECAM-1) as a predictive factor for invasion and proliferation in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.
AU - Tachezy, Michael
AU - Reichelt, Uta
AU - Melenberg, Tanja
AU - Gebauer, Florian
AU - Izbicki, Jakob R.
AU - Kaifi, Jussuf
PY - 2010
Y1 - 2010
N2 - Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic factors will help to address this. Angiogenesis plays an elementary role in the development of malignant tumors and may well also be important in the development of IPMN of the pancreas. Therefore we investigated endothelial cell marker CD31 (PECAM-1) and angiogenesis associated marker CD105 (endoglin) by immunohistochemistry.
AB - Intraductal papillary-mucinous neoplasm (IPMN) of the pancreas is an increasingly diagnosed entity since its definition by the World Health Organization in 1996. It has a broad clinical spectrum ranging from benign to malignant tumors. Optimum treatment is controversial and a better understanding of the development of IPMN of the pancreas and identification of potential prognostic factors will help to address this. Angiogenesis plays an elementary role in the development of malignant tumors and may well also be important in the development of IPMN of the pancreas. Therefore we investigated endothelial cell marker CD31 (PECAM-1) and angiogenesis associated marker CD105 (endoglin) by immunohistochemistry.
KW - Adult
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Immunohistochemistry
KW - Prognosis
KW - Time Factors
KW - Retrospective Studies
KW - Neoplasm Staging
KW - Cell Proliferation
KW - Kaplan-Meier Estimate
KW - Tumor Markers, Biological analysis
KW - Antigens, CD analysis
KW - Antigens, CD31 analysis
KW - Carcinoma, Pancreatic Ductal blood supply
KW - Carcinoma, Papillary blood supply
KW - Ki-67 Antigen analysis
KW - Neoplasm Invasiveness
KW - Neoplasms, Cystic, Mucinous, and Serous blood supply
KW - Neovascularization, Pathologic metabolism
KW - Pancreatic Neoplasms blood supply
KW - Receptors, Cell Surface analysis
KW - Adult
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Immunohistochemistry
KW - Prognosis
KW - Time Factors
KW - Retrospective Studies
KW - Neoplasm Staging
KW - Cell Proliferation
KW - Kaplan-Meier Estimate
KW - Tumor Markers, Biological analysis
KW - Antigens, CD analysis
KW - Antigens, CD31 analysis
KW - Carcinoma, Pancreatic Ductal blood supply
KW - Carcinoma, Papillary blood supply
KW - Ki-67 Antigen analysis
KW - Neoplasm Invasiveness
KW - Neoplasms, Cystic, Mucinous, and Serous blood supply
KW - Neovascularization, Pathologic metabolism
KW - Pancreatic Neoplasms blood supply
KW - Receptors, Cell Surface analysis
M3 - SCORING: Zeitschriftenaufsatz
VL - 25
SP - 1239
EP - 1246
JO - HISTOL HISTOPATHOL
JF - HISTOL HISTOPATHOL
SN - 0213-3911
IS - 10
M1 - 10
ER -