An update on ABO-incompatible kidney transplantation
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An update on ABO-incompatible kidney transplantation. / Zschiedrich, Stefan; Kramer-Zucker, Albrecht; Jänigen, Bernd; Seidl, Maximilian; Emmerich, Florian; Pisarski, Przemyslaw; Huber, Tobias B.
In: TRANSPL INT, Vol. 28, No. 4, 04.2015, p. 387-97.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
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TY - JOUR
T1 - An update on ABO-incompatible kidney transplantation
AU - Zschiedrich, Stefan
AU - Kramer-Zucker, Albrecht
AU - Jänigen, Bernd
AU - Seidl, Maximilian
AU - Emmerich, Florian
AU - Pisarski, Przemyslaw
AU - Huber, Tobias B
N1 - © 2014 Steunstichting ESOT.
PY - 2015/4
Y1 - 2015/4
N2 - ABO-incompatible kidney transplantation is nowadays a well-established procedure to expand living donor transplantation to blood group incompatible donor/recipient constellations. In the last two decades, transplantation protocols evolved to more specific isohaemagglutinin elimination techniques and established competent antirejection protection protocols without the need of splenectomy. ABOi kidney transplantation associated accommodation despite isohaemagglutinin reappearance, C4d positivity of peritubular capillaries as well as the increased incidence of bleeding complications is currently under intense investigation. However, most recent data show excellent graft survival rates equivalent to ABO-compatible kidney transplantation outcome.
AB - ABO-incompatible kidney transplantation is nowadays a well-established procedure to expand living donor transplantation to blood group incompatible donor/recipient constellations. In the last two decades, transplantation protocols evolved to more specific isohaemagglutinin elimination techniques and established competent antirejection protection protocols without the need of splenectomy. ABOi kidney transplantation associated accommodation despite isohaemagglutinin reappearance, C4d positivity of peritubular capillaries as well as the increased incidence of bleeding complications is currently under intense investigation. However, most recent data show excellent graft survival rates equivalent to ABO-compatible kidney transplantation outcome.
KW - ABO Blood-Group System
KW - Clinical Protocols
KW - Complement C4
KW - Graft Rejection
KW - Hemagglutinins
KW - Humans
KW - Immunoglobulins, Intravenous
KW - Immunologic Factors
KW - Kidney Transplantation
KW - Rituximab
KW - Transplantation Immunology
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
KW - Review
U2 - 10.1111/tri.12485
DO - 10.1111/tri.12485
M3 - SCORING: Review article
C2 - 25387763
VL - 28
SP - 387
EP - 397
JO - TRANSPL INT
JF - TRANSPL INT
SN - 0934-0874
IS - 4
ER -