An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?

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An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome? / Meyer-Schwesinger, Catherine.

In: KIDNEY INT, Vol. 95, No. 5, 05.2019, p. 1015-1017.

Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

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@article{d938b70340c0432d88ec4daa2dc921b4,
title = "An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?",
abstract = "In this issue of Kidney International, Jobst-Schwan et al. developed a zebrafish model of MAGI2-deficiency, which recapitulates findings of human nephrotic syndrome due to MAGI2 mutations. The authors use this model system to screen for drugs that might target and alleviate MAGI2-associated nephrotic syndrome pathways. The scientific context of this publication and the significance of its key findings are discussed in this commentary.",
keywords = "Adrenal Cortex Hormones, Animals, Humans, Nephrotic Syndrome, Podocytes, Zebrafish, Zebrafish Proteins",
author = "Catherine Meyer-Schwesinger",
note = "Editorial Material",
year = "2019",
month = may,
doi = "10.1016/j.kint.2019.01.044",
language = "English",
volume = "95",
pages = "1015--1017",
journal = "KIDNEY INT",
issn = "0085-2538",
publisher = "NATURE PUBLISHING GROUP",
number = "5",

}

RIS

TY - JOUR

T1 - An unexpected role of steroid on podocytes: from zebrafish to human nephrotic syndrome?

AU - Meyer-Schwesinger, Catherine

N1 - Editorial Material

PY - 2019/5

Y1 - 2019/5

N2 - In this issue of Kidney International, Jobst-Schwan et al. developed a zebrafish model of MAGI2-deficiency, which recapitulates findings of human nephrotic syndrome due to MAGI2 mutations. The authors use this model system to screen for drugs that might target and alleviate MAGI2-associated nephrotic syndrome pathways. The scientific context of this publication and the significance of its key findings are discussed in this commentary.

AB - In this issue of Kidney International, Jobst-Schwan et al. developed a zebrafish model of MAGI2-deficiency, which recapitulates findings of human nephrotic syndrome due to MAGI2 mutations. The authors use this model system to screen for drugs that might target and alleviate MAGI2-associated nephrotic syndrome pathways. The scientific context of this publication and the significance of its key findings are discussed in this commentary.

KW - Adrenal Cortex Hormones

KW - Animals

KW - Humans

KW - Nephrotic Syndrome

KW - Podocytes

KW - Zebrafish

KW - Zebrafish Proteins

U2 - 10.1016/j.kint.2019.01.044

DO - 10.1016/j.kint.2019.01.044

M3 - Other (editorial matter etc.)

C2 - 31010473

VL - 95

SP - 1015

EP - 1017

JO - KIDNEY INT

JF - KIDNEY INT

SN - 0085-2538

IS - 5

ER -