Alphastrahler Radium-223-Dichlorid: Neue Therapie beim kastrationsresistentes Prostatakarzinom mit symptomatischen Knochenmetastasen
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Alphastrahler Radium-223-Dichlorid: Neue Therapie beim kastrationsresistentes Prostatakarzinom mit symptomatischen Knochenmetastasen. / Heinzer, H; König, F; Klutmann, S.
In: UROLOGE, Vol. 53, No. 4, 01.04.2014, p. 519-523.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Alphastrahler Radium-223-Dichlorid: Neue Therapie beim kastrationsresistentes Prostatakarzinom mit symptomatischen Knochenmetastasen
AU - Heinzer, H
AU - König, F
AU - Klutmann, S
PY - 2014/4/1
Y1 - 2014/4/1
N2 - Radium-223 dichloride (Ra-223) is an alpha emitter with low toxicity for the treatment of patients with castrations-resistant prostate cancer (CRPC) and symptomatic bone metastases showing a 30% reduction in the risk of death, as compared to placebo. Because of the favorable physical and chemical characteristics, Ra-223 can be handled easily in daily practice based on interdisciplinary co-operation between urology and nuclear medicine. Ra-223 has been approved under the product name Xofigo® by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
AB - Radium-223 dichloride (Ra-223) is an alpha emitter with low toxicity for the treatment of patients with castrations-resistant prostate cancer (CRPC) and symptomatic bone metastases showing a 30% reduction in the risk of death, as compared to placebo. Because of the favorable physical and chemical characteristics, Ra-223 can be handled easily in daily practice based on interdisciplinary co-operation between urology and nuclear medicine. Ra-223 has been approved under the product name Xofigo® by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
KW - Alpha Particles
KW - Antineoplastic Agents
KW - Bone Neoplasms
KW - Clinical Trials as Topic
KW - Cooperative Behavior
KW - Dose-Response Relationship, Radiation
KW - Humans
KW - Interdisciplinary Communication
KW - Male
KW - Palliative Care
KW - Prostatic Neoplasms, Castration-Resistant
KW - Radioisotopes
KW - Radium
KW - Survival Rate
U2 - 10.1007/s00120-014-3436-1
DO - 10.1007/s00120-014-3436-1
M3 - SCORING: Zeitschriftenaufsatz
C2 - 24604017
VL - 53
SP - 519
EP - 523
JO - UROLOGE
JF - UROLOGE
SN - 0340-2592
IS - 4
ER -