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Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle?

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Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle? / Kiefer, F; Jahn, Holger; Schick, M; Wiedemann, Klaus.

In: ALCOHOL ALCOHOLISM, Vol. 37, No. 4, 4, 2002, p. 401-404.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Kiefer, F, Jahn, H, Schick, M & Wiedemann, K 2002, 'Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle?', ALCOHOL ALCOHOLISM, vol. 37, no. 4, 4, pp. 401-404. <http://www.ncbi.nlm.nih.gov/pubmed/12107045?dopt=Citation>

APA

Kiefer, F., Jahn, H., Schick, M., & Wiedemann, K. (2002). Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle? ALCOHOL ALCOHOLISM, 37(4), 401-404. [4]. http://www.ncbi.nlm.nih.gov/pubmed/12107045?dopt=Citation

Vancouver

Kiefer F, Jahn H, Schick M, Wiedemann K. Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle? ALCOHOL ALCOHOLISM. 2002;37(4):401-404. 4.

Bibtex

@article{04a0b2a14b8041bd8c0feb4be3d89bd0,
title = "Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle?",
abstract = "AIMS: Since the appetite-regulating peptide leptin was recently found to be highly correlated with both craving for alcohol and lifetime ethanol intake, the aim of our study was to test the hypothesis whether tumour necrosis factor-alpha (TNF-alpha) might be the factor that links alcohol intake with elevated leptin levels. METHODS: TNF-alpha, leptin, and alcohol craving were assessed in male alcohol addicts at the onset of alcohol withdrawal and in matched controls. RESULTS: Increased leptin plasma levels in alcohol addicts correlated significantly with an enhanced secretion of TNF-alpha, which was itself related to the duration of alcohol misuse. CONCLUSIONS: Since leptin was shown to be associated with alcohol craving, a possible vicious circle is suggested, including the components: alcohol intake, increase of TNF-alpha, enhanced leptin secretion, enhanced alcohol craving, and consecutively increased alcohol intake.",
author = "F Kiefer and Holger Jahn and M Schick and Klaus Wiedemann",
year = "2002",
language = "Deutsch",
volume = "37",
pages = "401--404",
journal = "ALCOHOL ALCOHOLISM",
issn = "0735-0414",
publisher = "Oxford University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Alcohol intake, tumour necrosis factor-alpha, leptin and craving: factors of a possibly vicious circle?

AU - Kiefer, F

AU - Jahn, Holger

AU - Schick, M

AU - Wiedemann, Klaus

PY - 2002

Y1 - 2002

N2 - AIMS: Since the appetite-regulating peptide leptin was recently found to be highly correlated with both craving for alcohol and lifetime ethanol intake, the aim of our study was to test the hypothesis whether tumour necrosis factor-alpha (TNF-alpha) might be the factor that links alcohol intake with elevated leptin levels. METHODS: TNF-alpha, leptin, and alcohol craving were assessed in male alcohol addicts at the onset of alcohol withdrawal and in matched controls. RESULTS: Increased leptin plasma levels in alcohol addicts correlated significantly with an enhanced secretion of TNF-alpha, which was itself related to the duration of alcohol misuse. CONCLUSIONS: Since leptin was shown to be associated with alcohol craving, a possible vicious circle is suggested, including the components: alcohol intake, increase of TNF-alpha, enhanced leptin secretion, enhanced alcohol craving, and consecutively increased alcohol intake.

AB - AIMS: Since the appetite-regulating peptide leptin was recently found to be highly correlated with both craving for alcohol and lifetime ethanol intake, the aim of our study was to test the hypothesis whether tumour necrosis factor-alpha (TNF-alpha) might be the factor that links alcohol intake with elevated leptin levels. METHODS: TNF-alpha, leptin, and alcohol craving were assessed in male alcohol addicts at the onset of alcohol withdrawal and in matched controls. RESULTS: Increased leptin plasma levels in alcohol addicts correlated significantly with an enhanced secretion of TNF-alpha, which was itself related to the duration of alcohol misuse. CONCLUSIONS: Since leptin was shown to be associated with alcohol craving, a possible vicious circle is suggested, including the components: alcohol intake, increase of TNF-alpha, enhanced leptin secretion, enhanced alcohol craving, and consecutively increased alcohol intake.

M3 - SCORING: Zeitschriftenaufsatz

VL - 37

SP - 401

EP - 404

JO - ALCOHOL ALCOHOLISM

JF - ALCOHOL ALCOHOLISM

SN - 0735-0414

IS - 4

M1 - 4

ER -