Age effects on interleukin-6 and interleukin-1beta responses to endurance exercise in patients with neuromuscular diseases.
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Age effects on interleukin-6 and interleukin-1beta responses to endurance exercise in patients with neuromuscular diseases. / Joerg Stuerenburg, H; Jung, Roman; Schoser, B G.
In: ARCH GERONTOL GERIAT, Vol. 29, No. 1, 1, 1999, p. 21-27.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Age effects on interleukin-6 and interleukin-1beta responses to endurance exercise in patients with neuromuscular diseases.
AU - Joerg Stuerenburg, H
AU - Jung, Roman
AU - Schoser, B G
PY - 1999
Y1 - 1999
N2 - Plasma IL-6 before and 20 min after prolonged muscular exercise for 20 min at the individual aerobic/anaerobic threshold was analyzed in patients with neuromuscular diseases and in controls. Patients were assigned to the following diagnostic categories: Controls (n=18); amyotrophic lateral sclerosis (n=7); peripheral neuropathy (n=6); muscular dystrophy (n=13); mitochondriopathy (n=3); myopathy (others) (n=3); inflammatory myopathy (n=6); mononeuropathy (n=4). The concentrations of IL-6 before exercise were 5.55+/-0.94 pg/ml, and 6.52+/-0.97 pg/ml after exercise (P=0.0001). We introduced the independent variables age, sex and diagnostic category into a stepwise multiple linear regression model. Age emerged as a significant predictor of the IL-6 ratio (IL-6 post exercise/lL-6 before exercise). The regression equation was: IL-6 ratio=0.87+0.009xage (years), R=0.33, P
AB - Plasma IL-6 before and 20 min after prolonged muscular exercise for 20 min at the individual aerobic/anaerobic threshold was analyzed in patients with neuromuscular diseases and in controls. Patients were assigned to the following diagnostic categories: Controls (n=18); amyotrophic lateral sclerosis (n=7); peripheral neuropathy (n=6); muscular dystrophy (n=13); mitochondriopathy (n=3); myopathy (others) (n=3); inflammatory myopathy (n=6); mononeuropathy (n=4). The concentrations of IL-6 before exercise were 5.55+/-0.94 pg/ml, and 6.52+/-0.97 pg/ml after exercise (P=0.0001). We introduced the independent variables age, sex and diagnostic category into a stepwise multiple linear regression model. Age emerged as a significant predictor of the IL-6 ratio (IL-6 post exercise/lL-6 before exercise). The regression equation was: IL-6 ratio=0.87+0.009xage (years), R=0.33, P
M3 - SCORING: Zeitschriftenaufsatz
VL - 29
SP - 21
EP - 27
JO - ARCH GERONTOL GERIAT
JF - ARCH GERONTOL GERIAT
SN - 0167-4943
IS - 1
M1 - 1
ER -
