Adherence to a lifestyle intervention - just a question of self-efficacy? Analysis of the AgeWell.de-intervention against cognitive decline

TY - JOUR

T1 - Adherence to a lifestyle intervention - just a question of self-efficacy? Analysis of the AgeWell.de-intervention against cognitive decline

AU - Wittmann, Felix G

AU - Pabst, Alexander

AU - Zülke, Andrea

AU - Luppa, Melanie

AU - Oey, Anke

AU - Boekholt, Melanie

AU - Weise, Solveig

AU - Fankhänel, Thomas

AU - Kosilek, Robert P

AU - Brettschneider, Christian

AU - Döhring, Juliane

AU - Lunden, Laura

AU - Wiese, Birgitt

AU - Hoffmann, Wolfgang

AU - Frese, Thomas

AU - Gensichen, Jochen

AU - König, Hans-Helmut

AU - Kaduszkiewicz, Hanna

AU - Thyrian, Jochen René

AU - Riedel-Heller, Steffi G

N1 - © 2024. The Author(s).

PY - 2024/6/22

Y1 - 2024/6/22

N2 - BACKGROUND: Aim of this study was to detect predictors of better adherence to the AgeWell.de-intervention, a two-year randomized multi-domain lifestyle intervention against cognitive decline.METHODS: Data of 317 intervention group-participants comprising a risk group for dementia (Cardiovascular Risk Factors, Ageing and Dementia (CAIDE) score of  ≥ 9; mean age 68.9 years, 49.5% women) from the AgeWell.de intervention study were analysed. Regression models with four blocks of predictors (sociodemographic, cognitive and psychosocial, lifestyle factors and chronic conditions) were run on adherence to the components of nutrition, enhancement of social and physical activity and cognitive training. Adherence to each component was operationalised by assessing the degree of goal achievement per component at up to seven time points during the intervention period, measured using a 5-point Likert scale (mean score of goal achievement).RESULTS: Increasing age was negatively associated with adherence, while higher education positively predicted adherence. Participants with better mental state (Montreal Cognitive Assessment (MoCA)-score > 25) at baseline and higher self-efficacy adhered better. Diabetes and cardiovascular conditions were not associated with adherence, whereas smoking negatively affected adherence. Highest education and quitting smoking in the past were the only predictors associated with all four intervention components.CONCLUSION: Results identified predictors for better and worse adherence. Particularly self-efficacy seems to be of considerable influence on adherence. This should be considered when designing future intervention trials.TRIAL REGISTRATION: German Clinical Trials Register (ref. number: DRKS00013555).

AB - BACKGROUND: Aim of this study was to detect predictors of better adherence to the AgeWell.de-intervention, a two-year randomized multi-domain lifestyle intervention against cognitive decline.METHODS: Data of 317 intervention group-participants comprising a risk group for dementia (Cardiovascular Risk Factors, Ageing and Dementia (CAIDE) score of  ≥ 9; mean age 68.9 years, 49.5% women) from the AgeWell.de intervention study were analysed. Regression models with four blocks of predictors (sociodemographic, cognitive and psychosocial, lifestyle factors and chronic conditions) were run on adherence to the components of nutrition, enhancement of social and physical activity and cognitive training. Adherence to each component was operationalised by assessing the degree of goal achievement per component at up to seven time points during the intervention period, measured using a 5-point Likert scale (mean score of goal achievement).RESULTS: Increasing age was negatively associated with adherence, while higher education positively predicted adherence. Participants with better mental state (Montreal Cognitive Assessment (MoCA)-score > 25) at baseline and higher self-efficacy adhered better. Diabetes and cardiovascular conditions were not associated with adherence, whereas smoking negatively affected adherence. Highest education and quitting smoking in the past were the only predictors associated with all four intervention components.CONCLUSION: Results identified predictors for better and worse adherence. Particularly self-efficacy seems to be of considerable influence on adherence. This should be considered when designing future intervention trials.TRIAL REGISTRATION: German Clinical Trials Register (ref. number: DRKS00013555).

KW - Humans

KW - Female

KW - Male

KW - Aged

KW - Cognitive Dysfunction/prevention & control

KW - Self Efficacy

KW - Life Style

KW - Patient Compliance/psychology

KW - Middle Aged

KW - Exercise/psychology

KW - Dementia/psychology

KW - Aged, 80 and over

U2 - 10.1186/s13195-024-01499-4

DO - 10.1186/s13195-024-01499-4

M3 - SCORING: Journal article

C2 - 38909256

VL - 16

SP - 133

JO - ALZHEIMERS RES THER

JF - ALZHEIMERS RES THER

SN - 1758-9193

ER -