Adenosine triphosphate stress dynamic perfusion CT imaging to identify myocardial ischemia: correlation with coronary CTA and invasive coronary angiography
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Adenosine triphosphate stress dynamic perfusion CT imaging to identify myocardial ischemia: correlation with coronary CTA and invasive coronary angiography. / Tahir, Enver; Kido, Teruhito; Tanabe, Yuki; Fukuyama, Naoki; Kido, Tomoyuki; Yamamura, Jin; Lund, Gunnar; Adam, Gerhard; Mochizuki, Teruhito.
Insights Imaging (2016) 7 (Suppl 1):S162–S465. 2016.Research output: SCORING: Contribution to book/anthology › Conference contribution - Published abstract for conference with selection process › Research › peer-review
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T1 - Adenosine triphosphate stress dynamic perfusion CT imaging to identify myocardial ischemia: correlation with coronary CTA and invasive coronary angiography
AU - Tahir, Enver
AU - Kido, Teruhito
AU - Tanabe, Yuki
AU - Fukuyama, Naoki
AU - Kido, Tomoyuki
AU - Yamamura, Jin
AU - Lund, Gunnar
AU - Adam, Gerhard
AU - Mochizuki, Teruhito
PY - 2016
Y1 - 2016
N2 - Methods and Materials: 30 patients underwent ATP stress dynamic CTP without table movement using a 256-slice MDCT and both CCTA and invasive coronary angiography (ICA). Dynamic CTP (whole heart datasets with 20 sample times in 40 beats in systole) was acquired with prospective ECG- gating. Obstructive CAD was defined as more than 50% stenosis on CTA or ICA, respectively. Quantitative CTP assessment of myocardium was performed according to the AHA 16 segment model. Myocardial peak CT attenuation value (HU), peak enhancement value (ΔHU), enhancement ratio (peak myocardial enhancement ΔHU / peak aortic enhancement ΔHU) and time to peak (ttp) enhancement were evaluated. Results: On CCTA 40 segments were classified as normal, 29 had coronary stenosis and 7 were excluded. CAG: 20 normal and 21 stenotic vessels. CCTA defined normal and ischemic myocardium showed mean peak CT attenuation values of 154±24 HU vs. 142±27 HU (p < 0.05), enhancement values of 100±23ΔHU vs. 87±25ΔHU (p < 0.05), enhancement ratios of 0.21±0.03 vs. 0.18±0.04 (p < 0.01) and ttp enhancement of 8.9±2.5s vs. 8.05±1.0s (p=0.49). ICA defined normal and ischemic myocardium showed mean peak CT attenuation values of 149±27HU vs. 142±34HU (p<0.05), enhancement values of 95±25ΔHU vs. 87±32ΔHU (p=0.39), enhancement ratios of 0.19±0.03 vs. 0.17±0.05 (p < 0.05) and ttp enhancement 8.3±1.5s vs. 8.2±1.0s (p=0.67). Conclusion: Ischaemic myocardium in the territory of stenotic coronary arteries can be identified using cut-off points for peak CT attenuation, enhancement and ehancement ratio.
AB - Methods and Materials: 30 patients underwent ATP stress dynamic CTP without table movement using a 256-slice MDCT and both CCTA and invasive coronary angiography (ICA). Dynamic CTP (whole heart datasets with 20 sample times in 40 beats in systole) was acquired with prospective ECG- gating. Obstructive CAD was defined as more than 50% stenosis on CTA or ICA, respectively. Quantitative CTP assessment of myocardium was performed according to the AHA 16 segment model. Myocardial peak CT attenuation value (HU), peak enhancement value (ΔHU), enhancement ratio (peak myocardial enhancement ΔHU / peak aortic enhancement ΔHU) and time to peak (ttp) enhancement were evaluated. Results: On CCTA 40 segments were classified as normal, 29 had coronary stenosis and 7 were excluded. CAG: 20 normal and 21 stenotic vessels. CCTA defined normal and ischemic myocardium showed mean peak CT attenuation values of 154±24 HU vs. 142±27 HU (p < 0.05), enhancement values of 100±23ΔHU vs. 87±25ΔHU (p < 0.05), enhancement ratios of 0.21±0.03 vs. 0.18±0.04 (p < 0.01) and ttp enhancement of 8.9±2.5s vs. 8.05±1.0s (p=0.49). ICA defined normal and ischemic myocardium showed mean peak CT attenuation values of 149±27HU vs. 142±34HU (p<0.05), enhancement values of 95±25ΔHU vs. 87±32ΔHU (p=0.39), enhancement ratios of 0.19±0.03 vs. 0.17±0.05 (p < 0.05) and ttp enhancement 8.3±1.5s vs. 8.2±1.0s (p=0.67). Conclusion: Ischaemic myocardium in the territory of stenotic coronary arteries can be identified using cut-off points for peak CT attenuation, enhancement and ehancement ratio.
M3 - Konferenzbeitrag - Abstract in Konferenzband
BT - Insights Imaging (2016) 7 (Suppl 1):S162–S465
ER -