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Adenomatoid odontogenic tumour of the mandible

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Adenomatoid odontogenic tumour of the mandible. / Friedrich, Reinhard E; Zustin, Jozef; Scheuer, Hanna A.

In: ANTICANCER RES, Vol. 30, No. 5, 01.05.2010, p. 1787-92.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Friedrich, RE, Zustin, J & Scheuer, HA 2010, 'Adenomatoid odontogenic tumour of the mandible', ANTICANCER RES, vol. 30, no. 5, pp. 1787-92.

APA

Friedrich, R. E., Zustin, J., & Scheuer, H. A. (2010). Adenomatoid odontogenic tumour of the mandible. ANTICANCER RES, 30(5), 1787-92.

Vancouver

Friedrich RE, Zustin J, Scheuer HA. Adenomatoid odontogenic tumour of the mandible. ANTICANCER RES. 2010 May 1;30(5):1787-92.

Bibtex

@article{dfe7018c391f49368d9a280e4054dde3,
title = "Adenomatoid odontogenic tumour of the mandible",
abstract = "Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin. The differential diagnosis of AOT is crucial in terms of surgical management. The 23-year old male patient presented in this case study was referred to the maxillofacial surgery clinic due to the incidental radiological finding of a large osteolytic lesion of the anterior mandible with a retained permanent canine at the base of the bone. Ultrasound imaging revealed the anterior surface of the tooth inside the lesion, indicating extreme thinning of the maintained cortical bone and liquid filling of the cystic lesion. Surgery revealed a bone defect with a deformed, incomplete tooth inside a granulation-like soft tissue. The tooth was extracted and the soft tissues were excavated. Healing was uneventful. Radiographic and physical investigations during long-term follow-up demonstrated complete bone remodeling. Some areas of the tumour were alpha-smooth-muscle-actin positive, indicating a myoepithelial differentiation. Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy. Exact morphological diagnosis avoids extensive ablative surgery.",
keywords = "Actins, Adult, Bone Remodeling, Cell Differentiation, Cell Membrane, Epithelium, Humans, Immunohistochemistry, Keratins, Male, Mandibular Neoplasms, Muscle, Smooth, Odontogenic Tumors",
author = "Friedrich, {Reinhard E} and Jozef Zustin and Scheuer, {Hanna A}",
year = "2010",
month = may,
day = "1",
language = "English",
volume = "30",
pages = "1787--92",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "5",

}

RIS

TY - JOUR

T1 - Adenomatoid odontogenic tumour of the mandible

AU - Friedrich, Reinhard E

AU - Zustin, Jozef

AU - Scheuer, Hanna A

PY - 2010/5/1

Y1 - 2010/5/1

N2 - Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin. The differential diagnosis of AOT is crucial in terms of surgical management. The 23-year old male patient presented in this case study was referred to the maxillofacial surgery clinic due to the incidental radiological finding of a large osteolytic lesion of the anterior mandible with a retained permanent canine at the base of the bone. Ultrasound imaging revealed the anterior surface of the tooth inside the lesion, indicating extreme thinning of the maintained cortical bone and liquid filling of the cystic lesion. Surgery revealed a bone defect with a deformed, incomplete tooth inside a granulation-like soft tissue. The tooth was extracted and the soft tissues were excavated. Healing was uneventful. Radiographic and physical investigations during long-term follow-up demonstrated complete bone remodeling. Some areas of the tumour were alpha-smooth-muscle-actin positive, indicating a myoepithelial differentiation. Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy. Exact morphological diagnosis avoids extensive ablative surgery.

AB - Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin. The differential diagnosis of AOT is crucial in terms of surgical management. The 23-year old male patient presented in this case study was referred to the maxillofacial surgery clinic due to the incidental radiological finding of a large osteolytic lesion of the anterior mandible with a retained permanent canine at the base of the bone. Ultrasound imaging revealed the anterior surface of the tooth inside the lesion, indicating extreme thinning of the maintained cortical bone and liquid filling of the cystic lesion. Surgery revealed a bone defect with a deformed, incomplete tooth inside a granulation-like soft tissue. The tooth was extracted and the soft tissues were excavated. Healing was uneventful. Radiographic and physical investigations during long-term follow-up demonstrated complete bone remodeling. Some areas of the tumour were alpha-smooth-muscle-actin positive, indicating a myoepithelial differentiation. Differential diagnosis of AOT to other odontogenic tumours, such as ameloblastoma, is crucial for therapy. Exact morphological diagnosis avoids extensive ablative surgery.

KW - Actins

KW - Adult

KW - Bone Remodeling

KW - Cell Differentiation

KW - Cell Membrane

KW - Epithelium

KW - Humans

KW - Immunohistochemistry

KW - Keratins

KW - Male

KW - Mandibular Neoplasms

KW - Muscle, Smooth

KW - Odontogenic Tumors

M3 - SCORING: Journal article

C2 - 20592380

VL - 30

SP - 1787

EP - 1792

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 5

ER -