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Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study

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Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study. / Vogler, Julia; Fink, Thomas; Sohns, Christian; Sommer, Philipp; Pott, Alexander; Dahme, Tillman; Rottner, Laura; Sciacca, Vanessa; Sieren, Malte Maria; Jacob, Fabian; Barkhausen, Jörg; Sano, Makoto; Eitel, Charlotte; Metzner, Andreas; Ouyang, Feifan; Kuck, Karl-Heinz; Tilz, Roland Richard; Heeger, Christian-Hendrik.

In: JACC-CLIN ELECTROPHY, Vol. 6, No. 7, 07.2020, p. 773-782.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Vogler, J, Fink, T, Sohns, C, Sommer, P, Pott, A, Dahme, T, Rottner, L, Sciacca, V, Sieren, MM, Jacob, F, Barkhausen, J, Sano, M, Eitel, C, Metzner, A, Ouyang, F, Kuck, K-H, Tilz, RR & Heeger, C-H 2020, 'Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study', JACC-CLIN ELECTROPHY, vol. 6, no. 7, pp. 773-782. https://doi.org/10.1016/j.jacep.2020.02.003

APA

Vogler, J., Fink, T., Sohns, C., Sommer, P., Pott, A., Dahme, T., Rottner, L., Sciacca, V., Sieren, M. M., Jacob, F., Barkhausen, J., Sano, M., Eitel, C., Metzner, A., Ouyang, F., Kuck, K-H., Tilz, R. R., & Heeger, C-H. (2020). Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study. JACC-CLIN ELECTROPHY, 6(7), 773-782. https://doi.org/10.1016/j.jacep.2020.02.003

Vancouver

Vogler J, Fink T, Sohns C, Sommer P, Pott A, Dahme T et al. Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study. JACC-CLIN ELECTROPHY. 2020 Jul;6(7):773-782. https://doi.org/10.1016/j.jacep.2020.02.003

Bibtex

@article{e0a8d1deba0d4b229567755c21cbe30a,
title = "Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study",
abstract = "OBJECTIVES: This study sought to assess the incidence, procedural characteristics, contributing factors, and clinical outcome of cryoballoon-based pulmonary vein isolation (CB-PVI)-related hemoptysis in a multicenter study.BACKGROUND: Hemoptysis has been described as a rare complication of CB-PVI. However, the precise mechanism and the etiology of this complication are poorly characterized.METHODS: Consecutive patients undergoing CB-PVI for paroxysmal or persistent atrial fibrillation at 4 German hospitals were included in this observational analysis.RESULTS: A total of 4,331 CB-PVI procedures were performed between 2006 and 2019. Fifteen patients (9 men, mean age 68.1 ± 9.8 years) developed acute hemoptysis during or within 24 h after CB-PVI, resulting in a hemoptysis frequency of 0.35%. Hemoptysis occurred in 6 of 720 procedures using the first-generation CB (0.83%) and in 9 of 3,611 procedures using the second-, third-, or fourth-generation CB (0.25%) (p = 0.015). Bronchoscopy was performed in 8 patients and showed bleeding exclusively due to mucosal injury or due to a coagulum at a bronchus adjacent to the ablation site. Hemoptysis resolved spontaneously without any long-term sequelae in all patients, except for a 92-year-old patient who died 13 days after CB-PVI due to pneumonia. No specific endobronchial treatment was necessary.CONCLUSIONS: Acute hemoptysis after CB-PVI is a rare but potentially life-threatening complication that is usually self-limiting. Direct thermal injury of bronchi adjacent to a pulmonary vein seems to be the most likely mechanism.",
keywords = "Aged, Aged, 80 and over, Catheter Ablation/adverse effects, Cryosurgery/adverse effects, Hemoptysis/epidemiology, Humans, Male, Pulmonary Veins/surgery, Treatment Outcome",
author = "Julia Vogler and Thomas Fink and Christian Sohns and Philipp Sommer and Alexander Pott and Tillman Dahme and Laura Rottner and Vanessa Sciacca and Sieren, {Malte Maria} and Fabian Jacob and J{\"o}rg Barkhausen and Makoto Sano and Charlotte Eitel and Andreas Metzner and Feifan Ouyang and Karl-Heinz Kuck and Tilz, {Roland Richard} and Christian-Hendrik Heeger",
note = "Copyright {\textcopyright} 2020 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.",
year = "2020",
month = jul,
doi = "10.1016/j.jacep.2020.02.003",
language = "English",
volume = "6",
pages = "773--782",
journal = "JACC-CLIN ELECTROPHY",
issn = "2405-500X",
publisher = "Elsevier USA",
number = "7",

}

RIS

TY - JOUR

T1 - Acute Hemoptysis Following Cryoballoon Pulmonary Vein Isolation: A Multicenter Study

AU - Vogler, Julia

AU - Fink, Thomas

AU - Sohns, Christian

AU - Sommer, Philipp

AU - Pott, Alexander

AU - Dahme, Tillman

AU - Rottner, Laura

AU - Sciacca, Vanessa

AU - Sieren, Malte Maria

AU - Jacob, Fabian

AU - Barkhausen, Jörg

AU - Sano, Makoto

AU - Eitel, Charlotte

AU - Metzner, Andreas

AU - Ouyang, Feifan

AU - Kuck, Karl-Heinz

AU - Tilz, Roland Richard

AU - Heeger, Christian-Hendrik

N1 - Copyright © 2020 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

PY - 2020/7

Y1 - 2020/7

N2 - OBJECTIVES: This study sought to assess the incidence, procedural characteristics, contributing factors, and clinical outcome of cryoballoon-based pulmonary vein isolation (CB-PVI)-related hemoptysis in a multicenter study.BACKGROUND: Hemoptysis has been described as a rare complication of CB-PVI. However, the precise mechanism and the etiology of this complication are poorly characterized.METHODS: Consecutive patients undergoing CB-PVI for paroxysmal or persistent atrial fibrillation at 4 German hospitals were included in this observational analysis.RESULTS: A total of 4,331 CB-PVI procedures were performed between 2006 and 2019. Fifteen patients (9 men, mean age 68.1 ± 9.8 years) developed acute hemoptysis during or within 24 h after CB-PVI, resulting in a hemoptysis frequency of 0.35%. Hemoptysis occurred in 6 of 720 procedures using the first-generation CB (0.83%) and in 9 of 3,611 procedures using the second-, third-, or fourth-generation CB (0.25%) (p = 0.015). Bronchoscopy was performed in 8 patients and showed bleeding exclusively due to mucosal injury or due to a coagulum at a bronchus adjacent to the ablation site. Hemoptysis resolved spontaneously without any long-term sequelae in all patients, except for a 92-year-old patient who died 13 days after CB-PVI due to pneumonia. No specific endobronchial treatment was necessary.CONCLUSIONS: Acute hemoptysis after CB-PVI is a rare but potentially life-threatening complication that is usually self-limiting. Direct thermal injury of bronchi adjacent to a pulmonary vein seems to be the most likely mechanism.

AB - OBJECTIVES: This study sought to assess the incidence, procedural characteristics, contributing factors, and clinical outcome of cryoballoon-based pulmonary vein isolation (CB-PVI)-related hemoptysis in a multicenter study.BACKGROUND: Hemoptysis has been described as a rare complication of CB-PVI. However, the precise mechanism and the etiology of this complication are poorly characterized.METHODS: Consecutive patients undergoing CB-PVI for paroxysmal or persistent atrial fibrillation at 4 German hospitals were included in this observational analysis.RESULTS: A total of 4,331 CB-PVI procedures were performed between 2006 and 2019. Fifteen patients (9 men, mean age 68.1 ± 9.8 years) developed acute hemoptysis during or within 24 h after CB-PVI, resulting in a hemoptysis frequency of 0.35%. Hemoptysis occurred in 6 of 720 procedures using the first-generation CB (0.83%) and in 9 of 3,611 procedures using the second-, third-, or fourth-generation CB (0.25%) (p = 0.015). Bronchoscopy was performed in 8 patients and showed bleeding exclusively due to mucosal injury or due to a coagulum at a bronchus adjacent to the ablation site. Hemoptysis resolved spontaneously without any long-term sequelae in all patients, except for a 92-year-old patient who died 13 days after CB-PVI due to pneumonia. No specific endobronchial treatment was necessary.CONCLUSIONS: Acute hemoptysis after CB-PVI is a rare but potentially life-threatening complication that is usually self-limiting. Direct thermal injury of bronchi adjacent to a pulmonary vein seems to be the most likely mechanism.

KW - Aged

KW - Aged, 80 and over

KW - Catheter Ablation/adverse effects

KW - Cryosurgery/adverse effects

KW - Hemoptysis/epidemiology

KW - Humans

KW - Male

KW - Pulmonary Veins/surgery

KW - Treatment Outcome

U2 - 10.1016/j.jacep.2020.02.003

DO - 10.1016/j.jacep.2020.02.003

M3 - SCORING: Journal article

C2 - 32703558

VL - 6

SP - 773

EP - 782

JO - JACC-CLIN ELECTROPHY

JF - JACC-CLIN ELECTROPHY

SN - 2405-500X

IS - 7

ER -