Acute and long-term success of left atrial anterior line and mitral isthmus line ablation in patients after mitral valve surgery

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Acute and long-term success of left atrial anterior line and mitral isthmus line ablation in patients after mitral valve surgery. / Bertels, Jana; Rottner, Laura; Heeger, Christian-Hendrik; Maurer, Tilman; Reissmann, Bruno; Ouyang, Feifan; Mathew, Shibu; Wohlmuth, Peter; Schlüter, Michael; Kuck, Karl-Heinz; Metzner, Andreas; Lemeš, Christine.

In: PACE, Vol. 45, No. 9, 09.2022, p. 1024-1031.

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@article{0c9c7e613b24472fab35c43b629d7799,
title = "Acute and long-term success of left atrial anterior line and mitral isthmus line ablation in patients after mitral valve surgery",
abstract = "BACKGROUND: Perimitral flutter and atrial fibrillation may occur in patients with prior surgical mitral valve (MV) repair or replacement and can be challenging for percutaneous catheter ablation. This study sought to determine the feasibility, acute success and durability of catheter ablation of atrial fibrillation or atrial tachycardia by way of a mitral isthmus line (MIL) or an anterior line (AL).METHODS: A total of 81 patients (49 males, mean age 62±11 years) with prior MV replacement (n = 30) or reconstruction (n = 51) underwent creation of a MIL (34) and/or an AL (72).RESULTS: Acute bidirectional block of the MIL was successfully achieved in 24/34 cases and of the AL in 64/72 patients. Patients of the control group without prior MV surgery were matched 1:1 with the valve group. In the AL control subgroup, acute bidirectional block was achieved in 65/72 patients. Acute blockage in the MIL control subgroup could be achieved in 31/34 patients. The MIL valve subgroup showed the worst results in terms of durability, whereas a similar trend emerged in the control group and the AL valve subgroup (probability of failure in MIL valve subgroup 2.224 vs. MIL control subgroup 0.605 [Hazard Ratio (HR) = 0.27, 95% confidence interval (CI), 0.11-0.65), P = .004]; probability of failure in AL valve subgroup 0.844 vs. AL control subgroup 1.03 [HR = 1.22 (95% CI, 0.66-2.26), P = .523]).CONCLUSIONS: Percutaneous creation of MIL and AL is feasible and safe in patients with prior MV replacement/repair and associated with moderate acute and long-term success rates to achieve bidirectional block.",
keywords = "Aged, Atrial Fibrillation/surgery, Catheter Ablation/methods, Heart Atria, Humans, Male, Middle Aged, Mitral Valve/surgery, Tachycardia, Supraventricular, Treatment Outcome",
author = "Jana Bertels and Laura Rottner and Christian-Hendrik Heeger and Tilman Maurer and Bruno Reissmann and Feifan Ouyang and Shibu Mathew and Peter Wohlmuth and Michael Schl{\"u}ter and Karl-Heinz Kuck and Andreas Metzner and Christine Leme{\v s}",
note = "{\textcopyright} 2022 Wiley Periodicals LLC.",
year = "2022",
month = sep,
doi = "10.1111/pace.14564",
language = "English",
volume = "45",
pages = "1024--1031",
journal = "PACE",
issn = "0147-8389",
publisher = "Wiley-Blackwell",
number = "9",

}

RIS

TY - JOUR

T1 - Acute and long-term success of left atrial anterior line and mitral isthmus line ablation in patients after mitral valve surgery

AU - Bertels, Jana

AU - Rottner, Laura

AU - Heeger, Christian-Hendrik

AU - Maurer, Tilman

AU - Reissmann, Bruno

AU - Ouyang, Feifan

AU - Mathew, Shibu

AU - Wohlmuth, Peter

AU - Schlüter, Michael

AU - Kuck, Karl-Heinz

AU - Metzner, Andreas

AU - Lemeš, Christine

N1 - © 2022 Wiley Periodicals LLC.

PY - 2022/9

Y1 - 2022/9

N2 - BACKGROUND: Perimitral flutter and atrial fibrillation may occur in patients with prior surgical mitral valve (MV) repair or replacement and can be challenging for percutaneous catheter ablation. This study sought to determine the feasibility, acute success and durability of catheter ablation of atrial fibrillation or atrial tachycardia by way of a mitral isthmus line (MIL) or an anterior line (AL).METHODS: A total of 81 patients (49 males, mean age 62±11 years) with prior MV replacement (n = 30) or reconstruction (n = 51) underwent creation of a MIL (34) and/or an AL (72).RESULTS: Acute bidirectional block of the MIL was successfully achieved in 24/34 cases and of the AL in 64/72 patients. Patients of the control group without prior MV surgery were matched 1:1 with the valve group. In the AL control subgroup, acute bidirectional block was achieved in 65/72 patients. Acute blockage in the MIL control subgroup could be achieved in 31/34 patients. The MIL valve subgroup showed the worst results in terms of durability, whereas a similar trend emerged in the control group and the AL valve subgroup (probability of failure in MIL valve subgroup 2.224 vs. MIL control subgroup 0.605 [Hazard Ratio (HR) = 0.27, 95% confidence interval (CI), 0.11-0.65), P = .004]; probability of failure in AL valve subgroup 0.844 vs. AL control subgroup 1.03 [HR = 1.22 (95% CI, 0.66-2.26), P = .523]).CONCLUSIONS: Percutaneous creation of MIL and AL is feasible and safe in patients with prior MV replacement/repair and associated with moderate acute and long-term success rates to achieve bidirectional block.

AB - BACKGROUND: Perimitral flutter and atrial fibrillation may occur in patients with prior surgical mitral valve (MV) repair or replacement and can be challenging for percutaneous catheter ablation. This study sought to determine the feasibility, acute success and durability of catheter ablation of atrial fibrillation or atrial tachycardia by way of a mitral isthmus line (MIL) or an anterior line (AL).METHODS: A total of 81 patients (49 males, mean age 62±11 years) with prior MV replacement (n = 30) or reconstruction (n = 51) underwent creation of a MIL (34) and/or an AL (72).RESULTS: Acute bidirectional block of the MIL was successfully achieved in 24/34 cases and of the AL in 64/72 patients. Patients of the control group without prior MV surgery were matched 1:1 with the valve group. In the AL control subgroup, acute bidirectional block was achieved in 65/72 patients. Acute blockage in the MIL control subgroup could be achieved in 31/34 patients. The MIL valve subgroup showed the worst results in terms of durability, whereas a similar trend emerged in the control group and the AL valve subgroup (probability of failure in MIL valve subgroup 2.224 vs. MIL control subgroup 0.605 [Hazard Ratio (HR) = 0.27, 95% confidence interval (CI), 0.11-0.65), P = .004]; probability of failure in AL valve subgroup 0.844 vs. AL control subgroup 1.03 [HR = 1.22 (95% CI, 0.66-2.26), P = .523]).CONCLUSIONS: Percutaneous creation of MIL and AL is feasible and safe in patients with prior MV replacement/repair and associated with moderate acute and long-term success rates to achieve bidirectional block.

KW - Aged

KW - Atrial Fibrillation/surgery

KW - Catheter Ablation/methods

KW - Heart Atria

KW - Humans

KW - Male

KW - Middle Aged

KW - Mitral Valve/surgery

KW - Tachycardia, Supraventricular

KW - Treatment Outcome

U2 - 10.1111/pace.14564

DO - 10.1111/pace.14564

M3 - SCORING: Journal article

C2 - 35822917

VL - 45

SP - 1024

EP - 1031

JO - PACE

JF - PACE

SN - 0147-8389

IS - 9

ER -