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Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease

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Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease. / Zengin, Elvin; Sinning, Christoph; Zeller, Tanja; Rupprecht, Hans-J; Schnabel, Renate B; Lackner, Karl-J; Blankenberg, Stefan; Westermann, Dirk; Bickel, Christoph.

In: BIOMARK MED, Vol. 9, No. 6, 2015, p. 597-604.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Zengin, E, Sinning, C, Zeller, T, Rupprecht, H-J, Schnabel, RB, Lackner, K-J, Blankenberg, S, Westermann, D & Bickel, C 2015, 'Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease', BIOMARK MED, vol. 9, no. 6, pp. 597-604. https://doi.org/10.2217/bmm.15.23

APA

Zengin, E., Sinning, C., Zeller, T., Rupprecht, H-J., Schnabel, R. B., Lackner, K-J., Blankenberg, S., Westermann, D., & Bickel, C. (2015). Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease. BIOMARK MED, 9(6), 597-604. https://doi.org/10.2217/bmm.15.23

Vancouver

Zengin E, Sinning C, Zeller T, Rupprecht H-J, Schnabel RB, Lackner K-J et al. Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease. BIOMARK MED. 2015;9(6):597-604. https://doi.org/10.2217/bmm.15.23

Bibtex

@article{8c747e6ea58c4b26b8929373b9457977,
title = "Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease",
abstract = "AIM: Superoxide dismutase (SOD) is important to control reactive oxygen species, but the relevance to human disease like coronary artery disease (CAD) and underlying ischemia/reperfusion injury is not clarified.METHODS: For this study, 2239 patients with known CAD were prospectively followed with a median follow-up time period of 3.6 years and a maximum of 6.9 years. During follow-up cardiovascular death was reported in 103 cases.RESULTS: SOD activity (log-transformed) was investigated as continuous and categorical variable, showing a significant influence on outcome in the fully adjusted model (p = 0.045).CONCLUSION: Increased SOD activity beyond the normal range in the human physiology is related to an adverse outcome in patients with CAD.",
keywords = "Aged, Biomarkers/blood, Coronary Artery Disease/blood, Female, Follow-Up Studies, Humans, Male, Middle Aged, Superoxide Dismutase/blood",
author = "Elvin Zengin and Christoph Sinning and Tanja Zeller and Hans-J Rupprecht and Schnabel, {Renate B} and Karl-J Lackner and Stefan Blankenberg and Dirk Westermann and Christoph Bickel",
year = "2015",
doi = "10.2217/bmm.15.23",
language = "English",
volume = "9",
pages = "597--604",
journal = "BIOMARK MED",
issn = "1752-0363",
publisher = "Future Medicine Ltd",
number = "6",

}

RIS

TY - JOUR

T1 - Activity of superoxide dismutase copper/zinc type and prognosis in a cohort of patients with coronary artery disease

AU - Zengin, Elvin

AU - Sinning, Christoph

AU - Zeller, Tanja

AU - Rupprecht, Hans-J

AU - Schnabel, Renate B

AU - Lackner, Karl-J

AU - Blankenberg, Stefan

AU - Westermann, Dirk

AU - Bickel, Christoph

PY - 2015

Y1 - 2015

N2 - AIM: Superoxide dismutase (SOD) is important to control reactive oxygen species, but the relevance to human disease like coronary artery disease (CAD) and underlying ischemia/reperfusion injury is not clarified.METHODS: For this study, 2239 patients with known CAD were prospectively followed with a median follow-up time period of 3.6 years and a maximum of 6.9 years. During follow-up cardiovascular death was reported in 103 cases.RESULTS: SOD activity (log-transformed) was investigated as continuous and categorical variable, showing a significant influence on outcome in the fully adjusted model (p = 0.045).CONCLUSION: Increased SOD activity beyond the normal range in the human physiology is related to an adverse outcome in patients with CAD.

AB - AIM: Superoxide dismutase (SOD) is important to control reactive oxygen species, but the relevance to human disease like coronary artery disease (CAD) and underlying ischemia/reperfusion injury is not clarified.METHODS: For this study, 2239 patients with known CAD were prospectively followed with a median follow-up time period of 3.6 years and a maximum of 6.9 years. During follow-up cardiovascular death was reported in 103 cases.RESULTS: SOD activity (log-transformed) was investigated as continuous and categorical variable, showing a significant influence on outcome in the fully adjusted model (p = 0.045).CONCLUSION: Increased SOD activity beyond the normal range in the human physiology is related to an adverse outcome in patients with CAD.

KW - Aged

KW - Biomarkers/blood

KW - Coronary Artery Disease/blood

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Superoxide Dismutase/blood

U2 - 10.2217/bmm.15.23

DO - 10.2217/bmm.15.23

M3 - SCORING: Journal article

C2 - 26079963

VL - 9

SP - 597

EP - 604

JO - BIOMARK MED

JF - BIOMARK MED

SN - 1752-0363

IS - 6

ER -