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Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral

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Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral. / Münkler, Paula; Kröger, Stefan; Liosis, Spyridon; Abdin, Amr; Lyan, Evgeny; Eitel, Charlotte; Eitel, Ingo; Meyer, Christian; Willems, Stephan; Heeger, Christian-Hendrik; Tilz, Roland Richard.

In: CIRC J, Vol. 82, No. 11, 25.10.2018, p. 2722-2727.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Münkler, P, Kröger, S, Liosis, S, Abdin, A, Lyan, E, Eitel, C, Eitel, I, Meyer, C, Willems, S, Heeger, C-H & Tilz, RR 2018, 'Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral', CIRC J, vol. 82, no. 11, pp. 2722-2727. https://doi.org/10.1253/circj.CJ-18-0361

APA

Münkler, P., Kröger, S., Liosis, S., Abdin, A., Lyan, E., Eitel, C., Eitel, I., Meyer, C., Willems, S., Heeger, C-H., & Tilz, R. R. (2018). Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral. CIRC J, 82(11), 2722-2727. https://doi.org/10.1253/circj.CJ-18-0361

Vancouver

Münkler P, Kröger S, Liosis S, Abdin A, Lyan E, Eitel C et al. Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral. CIRC J. 2018 Oct 25;82(11):2722-2727. https://doi.org/10.1253/circj.CJ-18-0361

Bibtex

@article{e8a304026b284db6aed8d017fdc7e82a,
title = "Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral",
abstract = "BACKGROUND: Key determinants for lesion formation in catheter ablation are contact force, radiofrequency (RF) power and time. The aim of this study was to evaluate the clinical applicability of ablation index (AI), a novel non-linear formula based on these components, and to compare AI with the conventional linear force-time interval (FTI) in pulmonary vein isolation (PVI). Methods and Results: Target AI ranges were defined for anatomical segments of the ipsilateral pulmonary veins. The operator was blinded to AI during PVI for the initial 11 patients (group A), and was unblinded for the remaining 23 patients (group B). We assessed (1) the clinical value of AI to avoid excessively high and low values with an operator blinded vs. non-blinded to AI; and (2) the relation of AI and FTI in predefined ranges. In group A, 235/564 lesions (41.7%) were in the predefined target range as compared with 1,171/1,412 lesions (82.9%) in group B (P<0.001). A given AI may correspond to a wide range of FTI, as reflected by a quartile coefficient of dispersion for AI of 0.11 vs. a quartile coefficient of dispersion for FTI of 0.36.CONCLUSIONS: Incorporating RF current power, the non-linear AI provides more comprehensive information during PVI compared with FTI. Given that the FTI for a given AI varies widely, the value of FTI in clinical practice is questionable.",
keywords = "Aged, Atrial Fibrillation/pathology, Catheter Ablation, Female, Humans, Male, Middle Aged, Pulmonary Veins/pathology",
author = "Paula M{\"u}nkler and Stefan Kr{\"o}ger and Spyridon Liosis and Amr Abdin and Evgeny Lyan and Charlotte Eitel and Ingo Eitel and Christian Meyer and Stephan Willems and Christian-Hendrik Heeger and Tilz, {Roland Richard}",
year = "2018",
month = oct,
day = "25",
doi = "10.1253/circj.CJ-18-0361",
language = "English",
volume = "82",
pages = "2722--2727",
journal = "CIRC J",
issn = "1346-9843",
publisher = "Japanese Circulation Society",
number = "11",

}

RIS

TY - JOUR

T1 - Ablation Index for Catheter Ablation of Atrial Fibrillation　- Clinical Applicability and Comparison With Force-Time Integral

AU - Münkler, Paula

AU - Kröger, Stefan

AU - Liosis, Spyridon

AU - Abdin, Amr

AU - Lyan, Evgeny

AU - Eitel, Charlotte

AU - Eitel, Ingo

AU - Meyer, Christian

AU - Willems, Stephan

AU - Heeger, Christian-Hendrik

AU - Tilz, Roland Richard

PY - 2018/10/25

Y1 - 2018/10/25

N2 - BACKGROUND: Key determinants for lesion formation in catheter ablation are contact force, radiofrequency (RF) power and time. The aim of this study was to evaluate the clinical applicability of ablation index (AI), a novel non-linear formula based on these components, and to compare AI with the conventional linear force-time interval (FTI) in pulmonary vein isolation (PVI). Methods and Results: Target AI ranges were defined for anatomical segments of the ipsilateral pulmonary veins. The operator was blinded to AI during PVI for the initial 11 patients (group A), and was unblinded for the remaining 23 patients (group B). We assessed (1) the clinical value of AI to avoid excessively high and low values with an operator blinded vs. non-blinded to AI; and (2) the relation of AI and FTI in predefined ranges. In group A, 235/564 lesions (41.7%) were in the predefined target range as compared with 1,171/1,412 lesions (82.9%) in group B (P<0.001). A given AI may correspond to a wide range of FTI, as reflected by a quartile coefficient of dispersion for AI of 0.11 vs. a quartile coefficient of dispersion for FTI of 0.36.CONCLUSIONS: Incorporating RF current power, the non-linear AI provides more comprehensive information during PVI compared with FTI. Given that the FTI for a given AI varies widely, the value of FTI in clinical practice is questionable.

AB - BACKGROUND: Key determinants for lesion formation in catheter ablation are contact force, radiofrequency (RF) power and time. The aim of this study was to evaluate the clinical applicability of ablation index (AI), a novel non-linear formula based on these components, and to compare AI with the conventional linear force-time interval (FTI) in pulmonary vein isolation (PVI). Methods and Results: Target AI ranges were defined for anatomical segments of the ipsilateral pulmonary veins. The operator was blinded to AI during PVI for the initial 11 patients (group A), and was unblinded for the remaining 23 patients (group B). We assessed (1) the clinical value of AI to avoid excessively high and low values with an operator blinded vs. non-blinded to AI; and (2) the relation of AI and FTI in predefined ranges. In group A, 235/564 lesions (41.7%) were in the predefined target range as compared with 1,171/1,412 lesions (82.9%) in group B (P<0.001). A given AI may correspond to a wide range of FTI, as reflected by a quartile coefficient of dispersion for AI of 0.11 vs. a quartile coefficient of dispersion for FTI of 0.36.CONCLUSIONS: Incorporating RF current power, the non-linear AI provides more comprehensive information during PVI compared with FTI. Given that the FTI for a given AI varies widely, the value of FTI in clinical practice is questionable.

KW - Aged

KW - Atrial Fibrillation/pathology

KW - Catheter Ablation

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Pulmonary Veins/pathology

U2 - 10.1253/circj.CJ-18-0361

DO - 10.1253/circj.CJ-18-0361

M3 - SCORING: Journal article

C2 - 30197409

VL - 82

SP - 2722

EP - 2727

JO - CIRC J

JF - CIRC J

SN - 1346-9843

IS - 11

ER -