A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer

Dirk Rades; Liesa Dziggel; Stefan Janssen; Oliver Blanck; Dagmar Hornung; Steven E Schild

A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer

Standard

A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer. / Rades, Dirk; Dziggel, Liesa; Janssen, Stefan; Blanck, Oliver; Hornung, Dagmar; Schild, Steven E.

In: ANTICANCER RES, Vol. 36, No. 3, 03.2016, p. 1073-6.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Rades, D, Dziggel, L, Janssen, S, Blanck, O, Hornung, D & Schild, SE 2016, 'A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer', ANTICANCER RES, vol. 36, no. 3, pp. 1073-6.

APA

Rades, D., Dziggel, L., Janssen, S., Blanck, O., Hornung, D., & Schild, S. E. (2016). A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer. ANTICANCER RES, 36(3), 1073-6.

Vancouver

Rades D, Dziggel L, Janssen S, Blanck O, Hornung D, Schild SE. A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer. ANTICANCER RES. 2016 Mar;36(3):1073-6.

Bibtex

@article{6527ce8070aa4637ac62b419b73bad89,

title = "A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer",

abstract = "AIM: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases.PATIENTS AND METHODS: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient.RESULTS: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001).CONCLUSION: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.",

keywords = "Brain Neoplasms, Breast Neoplasms, Female, Humans, Karnofsky Performance Status, Middle Aged, Prognosis, Radiosurgery, Survival Rate, Treatment Outcome, Journal Article",

author = "Dirk Rades and Liesa Dziggel and Stefan Janssen and Oliver Blanck and Dagmar Hornung and Schild, {Steven E}",

year = "2016",

month = mar,

language = "English",

volume = "36",

pages = "1073--6",

journal = "ANTICANCER RES",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "3",

}

RIS

TY - JOUR

T1 - A Survival Score for Patients Receiving Stereotactic Radiosurgery Alone for Brain Metastases from Breast Cancer

AU - Rades, Dirk

AU - Dziggel, Liesa

AU - Janssen, Stefan

AU - Blanck, Oliver

AU - Hornung, Dagmar

AU - Schild, Steven E

PY - 2016/3

Y1 - 2016/3

N2 - AIM: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases.PATIENTS AND METHODS: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient.RESULTS: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001).CONCLUSION: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.

AB - AIM: To generate a survival score for patients with breast cancer treated with stereotactic radiosurgery (SRS) alone for brain metastases.PATIENTS AND METHODS: Seven factors were evaluated in 34 patients, namely age, performance score, number of brain metastases, maximum diameter of all brain metastases, location of brain metastases, extracerebral metastases and time between breast cancer diagnosis and SRS. The score was created from factors having a significant impact on survival. Points of 0 (worse survival) or 1 (better survival) were assigned. Factor scores were added to total prognostic scores for each patient.RESULTS: A significant impact on survival was found for performance score (p<0.001), maximum diameter of cerebral lesions (p=0.002), and extracerebral metastases (p=0.026). Three groups were designated by score: 0-1, 2 and 3 points. One-year survival rates were 48%, 71% and 100%, respectively (p<0.001).CONCLUSION: This score contributes to appropriate selection of personalized treatment in patients with breast cancer with few cerebral metastases.

KW - Brain Neoplasms

KW - Breast Neoplasms

KW - Female

KW - Humans

KW - Karnofsky Performance Status

KW - Middle Aged

KW - Prognosis

KW - Radiosurgery

KW - Survival Rate

KW - Treatment Outcome

KW - Journal Article

M3 - SCORING: Journal article

C2 - 26977000

VL - 36

SP - 1073

EP - 1076

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 3

ER -