A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.

Stefanie Meyer; Thomas J Fuchs; Anja K Bosserhoff; Ferdinand Hofstädter; Armin Pauer; Volker Roth; Joachim M Buhmann; Ingrid Moll; Nikos Anagnostou; Johanna Brandner; Kristian Ikenberg; Holger Moch; Michael Landthaler; Thomas Vogt; Peter J Wild

doi:10.1371/journal.pone.0038222

A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.

Stefanie Meyer
Thomas J Fuchs
Anja K Bosserhoff
Ferdinand Hofstädter
Armin Pauer
Volker Roth
Joachim M Buhmann
Ingrid Moll
Nikos Anagnostou
Johanna Brandner
Kristian Ikenberg
Holger Moch
Michael Landthaler
Thomas Vogt
Peter J Wild

Related Research units

Department of Dermatology and Venereology

Abstract

Current staging methods such as tumor thickness, ulceration and invasion of the sentinel node are known to be prognostic parameters in patients with malignant melanoma (MM). However, predictive molecular marker profiles for risk stratification and therapy optimization are not yet available for routine clinical assessment.

Bibliographical data

Original language	English
Article number	6
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0038222
Publication status	Published - 2012

pubmed	22685558