A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies

Standard

A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies. / Janssen, Stefan; Bajrovic, Amira; Schild, Steven E; Rades, Dirk.

In: ANTICANCER RES, Vol. 36, No. 10, 10.2016, p. 5469-5472.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

APA

Vancouver

Bibtex

@article{9df5fd3b0fd74e3f938a38d984250d69,
title = "A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies",
abstract = "AIM: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies.PATIENTS AND METHODS: In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument.RESULTS: On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001).CONCLUSION: An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.",
keywords = "Female, Genital Neoplasms, Female, Humans, Middle Aged, Prognosis, Spinal Cord Compression, Spinal Neoplasms, Survival Rate, Journal Article",
author = "Stefan Janssen and Amira Bajrovic and Schild, {Steven E} and Dirk Rades",
note = "Copyright{\textcopyright} 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.",
year = "2016",
month = oct,
doi = "10.21873/anticanres.11127",
language = "English",
volume = "36",
pages = "5469--5472",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "10",

}

RIS

TY - JOUR

T1 - A Scoring Instrument to Predict the Survival Prognoses of Patients with Metastatic Epidural Spinal Cord Compression from Gynecological Malignancies

AU - Janssen, Stefan

AU - Bajrovic, Amira

AU - Schild, Steven E

AU - Rades, Dirk

N1 - Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

PY - 2016/10

Y1 - 2016/10

N2 - AIM: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies.PATIENTS AND METHODS: In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument.RESULTS: On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001).CONCLUSION: An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.

AB - AIM: To design a scoring instrument for rating overall survival (OS) of patients with metastatic epidural sinal cord compression (MESCC) from gynecological malignancies.PATIENTS AND METHODS: In 22 patients treated with radiotherapy alone for MESCC from gynecological malignancies, ten factors were analyzed for effects on OS. Factors significantly associated with OS on multivariate analysis were included in a scoring instrument.RESULTS: On multivariate analyses, no visceral metastases (p=0.004) and affection of 1-2 vertebrae (p=0.012) were significant. Scoring points for each factor were 0 or 1, depending on OS rates. After summing, scores of 0 (n=6), 1 (n=9) or 2 points (n=9) were obtained. OS rates were 0%, 78% and 100%, respectively, at 3 months and 0%, 33% and 86%, respectively, at 6 months (p<0.001).CONCLUSION: An instrument was developed for estimating the lifespan of patients with MESCC from gynecological malignancies. This instrument can support physicians when picking an individual treatment.

KW - Female

KW - Genital Neoplasms, Female

KW - Humans

KW - Middle Aged

KW - Prognosis

KW - Spinal Cord Compression

KW - Spinal Neoplasms

KW - Survival Rate

KW - Journal Article

U2 - 10.21873/anticanres.11127

DO - 10.21873/anticanres.11127

M3 - SCORING: Journal article

C2 - 27798917

VL - 36

SP - 5469

EP - 5472

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 10

ER -