A Protocol for Rat Kidney Normothermic Machine Perfusion and Subsequent Transplantation

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A Protocol for Rat Kidney Normothermic Machine Perfusion and Subsequent Transplantation. / Czogalla, Jan; Grahammer, Florian; Puelles, Victor G; Huber, Tobias B.

In: ARTIF ORGANS, Vol. 45, No. 2, 02.2021, p. 168-174.

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@article{fd0e5ea0ac884de38cf2b15ceccad51a,
title = "A Protocol for Rat Kidney Normothermic Machine Perfusion and Subsequent Transplantation",
abstract = "End-stage renal disease is a major global health burden. The only definitive treatment existing is renal transplantation. Worldwide, the demand for donated kidneys by far exceeds the supply. A novel technique for organ preservation, normothermic machine perfusion (NMP), now promises to increase the potential pool of available organs by extending the spectrum of donors and reducing the incidence of graft failure. First studies in humans and large animals are being performed with promising results, but refinement of the technique, buffer, and machines involved is labor-intensive and expensive. To our knowledge, this is the first report of a small animal model of NMP and subsequent transplantation.",
author = "Jan Czogalla and Florian Grahammer and Puelles, {Victor G} and Huber, {Tobias B}",
note = "{\textcopyright} 2020 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation and Wiley Periodicals LLC.",
year = "2021",
month = feb,
doi = "10.1111/aor.13799",
language = "English",
volume = "45",
pages = "168--174",
journal = "ARTIF ORGANS",
issn = "0160-564X",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - A Protocol for Rat Kidney Normothermic Machine Perfusion and Subsequent Transplantation

AU - Czogalla, Jan

AU - Grahammer, Florian

AU - Puelles, Victor G

AU - Huber, Tobias B

N1 - © 2020 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation and Wiley Periodicals LLC.

PY - 2021/2

Y1 - 2021/2

N2 - End-stage renal disease is a major global health burden. The only definitive treatment existing is renal transplantation. Worldwide, the demand for donated kidneys by far exceeds the supply. A novel technique for organ preservation, normothermic machine perfusion (NMP), now promises to increase the potential pool of available organs by extending the spectrum of donors and reducing the incidence of graft failure. First studies in humans and large animals are being performed with promising results, but refinement of the technique, buffer, and machines involved is labor-intensive and expensive. To our knowledge, this is the first report of a small animal model of NMP and subsequent transplantation.

AB - End-stage renal disease is a major global health burden. The only definitive treatment existing is renal transplantation. Worldwide, the demand for donated kidneys by far exceeds the supply. A novel technique for organ preservation, normothermic machine perfusion (NMP), now promises to increase the potential pool of available organs by extending the spectrum of donors and reducing the incidence of graft failure. First studies in humans and large animals are being performed with promising results, but refinement of the technique, buffer, and machines involved is labor-intensive and expensive. To our knowledge, this is the first report of a small animal model of NMP and subsequent transplantation.

U2 - 10.1111/aor.13799

DO - 10.1111/aor.13799

M3 - SCORING: Journal article

C2 - 32780541

VL - 45

SP - 168

EP - 174

JO - ARTIF ORGANS

JF - ARTIF ORGANS

SN - 0160-564X

IS - 2

ER -