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A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer

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A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer. / Rades, Dirk; Huttenlocher, Stefan; Dziggel, Liesa; Khoa, Mai Trong; Van Thai, Pham; Hornung, Dagmar; Schild, Steven E.

In: LUNG, Vol. 193, No. 2, 04.2015, p. 299-302.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Rades, D, Huttenlocher, S, Dziggel, L, Khoa, MT, Van Thai, P, Hornung, D & Schild, SE 2015, 'A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer', LUNG, vol. 193, no. 2, pp. 299-302. https://doi.org/10.1007/s00408-014-9676-4

APA

Rades, D., Huttenlocher, S., Dziggel, L., Khoa, M. T., Van Thai, P., Hornung, D., & Schild, S. E. (2015). A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer. LUNG, 193(2), 299-302. https://doi.org/10.1007/s00408-014-9676-4

Vancouver

Rades D, Huttenlocher S, Dziggel L, Khoa MT, Van Thai P, Hornung D et al. A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer. LUNG. 2015 Apr;193(2):299-302. https://doi.org/10.1007/s00408-014-9676-4

Bibtex

@article{044cf98bf83a43229fb082206bf59dc4,
title = "A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer",
abstract = "Radiosurgery is frequently used for patients with few cerebral metastases. Decisions regarding personalized treatment should include the patient's survival prognosis. Prognostic tools should be available for estimating the remaining lifetime for each primary tumor and treatment. We designed such a tool for patients receiving radiosurgery alone for cerebral metastases from lung cancer. Ten variables were analyzed in 98 patients. On multivariate analysis, extra-cranial spread was significantly associated with worse survival (p < 0.001). A trend was observed for poorer performance status (p = 0.08) and greater diameter of cerebral lesions (p = 0.07). Points for the tool were derived from 12-month survival rates of these variables and added, resulting in sum scores of 10-16 points. Three groups were built, 10-12, 14-15, and 16 points with 12-month survival rates of 22, 52, and 79% (p < 0.001). This new tool enables physicians to estimate the survival of lung cancer patients with few cerebral metastases which should impact individualized treatment choices.",
author = "Dirk Rades and Stefan Huttenlocher and Liesa Dziggel and Khoa, {Mai Trong} and {Van Thai}, Pham and Dagmar Hornung and Schild, {Steven E}",
year = "2015",
month = apr,
doi = "10.1007/s00408-014-9676-4",
language = "English",
volume = "193",
pages = "299--302",
journal = "LUNG",
issn = "0341-2040",
publisher = "Springer New York",
number = "2",

}

RIS

TY - JOUR

T1 - A new tool predicting survival after radiosurgery alone for one or two cerebral metastases from lung cancer

AU - Rades, Dirk

AU - Huttenlocher, Stefan

AU - Dziggel, Liesa

AU - Khoa, Mai Trong

AU - Van Thai, Pham

AU - Hornung, Dagmar

AU - Schild, Steven E

PY - 2015/4

Y1 - 2015/4

N2 - Radiosurgery is frequently used for patients with few cerebral metastases. Decisions regarding personalized treatment should include the patient's survival prognosis. Prognostic tools should be available for estimating the remaining lifetime for each primary tumor and treatment. We designed such a tool for patients receiving radiosurgery alone for cerebral metastases from lung cancer. Ten variables were analyzed in 98 patients. On multivariate analysis, extra-cranial spread was significantly associated with worse survival (p < 0.001). A trend was observed for poorer performance status (p = 0.08) and greater diameter of cerebral lesions (p = 0.07). Points for the tool were derived from 12-month survival rates of these variables and added, resulting in sum scores of 10-16 points. Three groups were built, 10-12, 14-15, and 16 points with 12-month survival rates of 22, 52, and 79% (p < 0.001). This new tool enables physicians to estimate the survival of lung cancer patients with few cerebral metastases which should impact individualized treatment choices.

AB - Radiosurgery is frequently used for patients with few cerebral metastases. Decisions regarding personalized treatment should include the patient's survival prognosis. Prognostic tools should be available for estimating the remaining lifetime for each primary tumor and treatment. We designed such a tool for patients receiving radiosurgery alone for cerebral metastases from lung cancer. Ten variables were analyzed in 98 patients. On multivariate analysis, extra-cranial spread was significantly associated with worse survival (p < 0.001). A trend was observed for poorer performance status (p = 0.08) and greater diameter of cerebral lesions (p = 0.07). Points for the tool were derived from 12-month survival rates of these variables and added, resulting in sum scores of 10-16 points. Three groups were built, 10-12, 14-15, and 16 points with 12-month survival rates of 22, 52, and 79% (p < 0.001). This new tool enables physicians to estimate the survival of lung cancer patients with few cerebral metastases which should impact individualized treatment choices.

U2 - 10.1007/s00408-014-9676-4

DO - 10.1007/s00408-014-9676-4

M3 - SCORING: Journal article

C2 - 25528743

VL - 193

SP - 299

EP - 302

JO - LUNG

JF - LUNG

SN - 0341-2040

IS - 2

ER -