A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen

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A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen. / Kirchhoff, C.

In: BIOL REPROD, Vol. 50, No. 4, 04.1994, p. 896-902.

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@article{4ac64f122b5c43fba0702d43362aa4e0,
title = "A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen",
abstract = "The adult rodent epididymis and seminal vesicles were shown by polymerase chain reaction (PCR) cloning. Northern blot analysis, and in situ hybridization to be major expression sites of an mRNA encoding a small glycosylphosphatidylinositol (GPI)-anchored cell surface antigen that has been previously described as the mouse lymphocyte differentiation antigen B7, herein referred to as MB7. Sequence comparison of the corresponding epididymal cDNAs from the mouse (MB7) and the rat (RB7) revealed an unexpected divergence in the peptide coding regions of these homologous genes. A possible functional relationship to the human sperm surface and lymphocyte differentiation antigen CDw52/HE5 is discussed with respect to the highly variable mature peptide coding regions.",
keywords = "Amino Acid Sequence, Animals, Antigens, CD80, Base Sequence, Blotting, Northern, Cloning, Molecular, DNA, Complementary, Epididymis, Glycosylphosphatidylinositols, In Situ Hybridization, Male, Mice, Mice, Inbred C57BL, Molecular Sequence Data, Polymerase Chain Reaction, RNA, Messenger, Rats, Rats, Wistar, Sequence Homology",
author = "C Kirchhoff",
year = "1994",
month = apr,
language = "English",
volume = "50",
pages = "896--902",
journal = "BIOL REPROD",
issn = "0006-3363",
publisher = "Society for the Study of Reproduction",
number = "4",

}

RIS

TY - JOUR

T1 - A major messenger ribonucleic acid of the rodent epididymis encodes a small glycosylphosphatidylinositol-anchored lymphocyte surface antigen

AU - Kirchhoff, C

PY - 1994/4

Y1 - 1994/4

N2 - The adult rodent epididymis and seminal vesicles were shown by polymerase chain reaction (PCR) cloning. Northern blot analysis, and in situ hybridization to be major expression sites of an mRNA encoding a small glycosylphosphatidylinositol (GPI)-anchored cell surface antigen that has been previously described as the mouse lymphocyte differentiation antigen B7, herein referred to as MB7. Sequence comparison of the corresponding epididymal cDNAs from the mouse (MB7) and the rat (RB7) revealed an unexpected divergence in the peptide coding regions of these homologous genes. A possible functional relationship to the human sperm surface and lymphocyte differentiation antigen CDw52/HE5 is discussed with respect to the highly variable mature peptide coding regions.

AB - The adult rodent epididymis and seminal vesicles were shown by polymerase chain reaction (PCR) cloning. Northern blot analysis, and in situ hybridization to be major expression sites of an mRNA encoding a small glycosylphosphatidylinositol (GPI)-anchored cell surface antigen that has been previously described as the mouse lymphocyte differentiation antigen B7, herein referred to as MB7. Sequence comparison of the corresponding epididymal cDNAs from the mouse (MB7) and the rat (RB7) revealed an unexpected divergence in the peptide coding regions of these homologous genes. A possible functional relationship to the human sperm surface and lymphocyte differentiation antigen CDw52/HE5 is discussed with respect to the highly variable mature peptide coding regions.

KW - Amino Acid Sequence

KW - Animals

KW - Antigens, CD80

KW - Base Sequence

KW - Blotting, Northern

KW - Cloning, Molecular

KW - DNA, Complementary

KW - Epididymis

KW - Glycosylphosphatidylinositols

KW - In Situ Hybridization

KW - Male

KW - Mice

KW - Mice, Inbred C57BL

KW - Molecular Sequence Data

KW - Polymerase Chain Reaction

KW - RNA, Messenger

KW - Rats

KW - Rats, Wistar

KW - Sequence Homology

M3 - SCORING: Journal article

C2 - 7515288

VL - 50

SP - 896

EP - 902

JO - BIOL REPROD

JF - BIOL REPROD

SN - 0006-3363

IS - 4

ER -