A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect
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A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect. / Jaya, E S; Ascone, L; Lincoln, T M.
In: PSYCHOL MED, Vol. 48, No. 8, 06.2018, p. 1299-1307.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - A longitudinal mediation analysis of the effect of negative-self-schemas on positive symptoms via negative affect
AU - Jaya, E S
AU - Ascone, L
AU - Lincoln, T M
PY - 2018/6
Y1 - 2018/6
N2 - BACKGROUND: Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design.METHODS: A longitudinal cohort design in an online community sample (N = 962) from Germany, Indonesia, and the USA was used. NSS, negative affect and positive symptoms were measured at four time-points (T0-T3) over a 1-year period. Cross-lagged panel and longitudinal mediation analyses with structural equation modeling were used to test the temporal mediation.RESULTS: Independent cross-lagged panel models showed a significant unidirectional longitudinal path from NSS to positive symptoms (T2-T3, β = 0.18, p < 0.01) and bidirectional longitudinal associations from NSS to negative affect (T0-T1, γ = 0.14, p < 0.01) and vice versa (T0-T1, γ = 0.19, p < 0.01). There was also a significant indirect pathway from NSS at baseline via negative affect at T1 and T2 to positive symptoms at T3 (unstandardized indirect effect coefficient = 0.020, p < 0.05, BCa CI 0.004-0.035), indicating mediation.CONCLUSIONS: Our findings support the postulated affective pathway from NSS to positive symptoms via negative affect. Specifically, our data indicate that NSS and negative affect influence each other and build up over the course of several months before leading on to positive symptoms. We conclude that interrupting this process by targeting NSS and negative affect early in the process could be a promising strategy to prevent the exacerbation of positive symptoms.
AB - BACKGROUND: Cognitive models postulate that negative-self-schemas (NSS) cause and maintain positive symptoms and that negative affect mediates this link. However, only few studies have tested the temporal mediation claim systematically using an appropriate design.METHODS: A longitudinal cohort design in an online community sample (N = 962) from Germany, Indonesia, and the USA was used. NSS, negative affect and positive symptoms were measured at four time-points (T0-T3) over a 1-year period. Cross-lagged panel and longitudinal mediation analyses with structural equation modeling were used to test the temporal mediation.RESULTS: Independent cross-lagged panel models showed a significant unidirectional longitudinal path from NSS to positive symptoms (T2-T3, β = 0.18, p < 0.01) and bidirectional longitudinal associations from NSS to negative affect (T0-T1, γ = 0.14, p < 0.01) and vice versa (T0-T1, γ = 0.19, p < 0.01). There was also a significant indirect pathway from NSS at baseline via negative affect at T1 and T2 to positive symptoms at T3 (unstandardized indirect effect coefficient = 0.020, p < 0.05, BCa CI 0.004-0.035), indicating mediation.CONCLUSIONS: Our findings support the postulated affective pathway from NSS to positive symptoms via negative affect. Specifically, our data indicate that NSS and negative affect influence each other and build up over the course of several months before leading on to positive symptoms. We conclude that interrupting this process by targeting NSS and negative affect early in the process could be a promising strategy to prevent the exacerbation of positive symptoms.
KW - Adolescent
KW - Adult
KW - Affect
KW - Aged
KW - Anxiety/psychology
KW - Depression/psychology
KW - Female
KW - Germany
KW - Humans
KW - Indonesia
KW - Longitudinal Studies
KW - Male
KW - Middle Aged
KW - Models, Psychological
KW - Psychiatric Status Rating Scales
KW - Psychotic Disorders/psychology
KW - Regression Analysis
KW - Self Concept
KW - Surveys and Questionnaires
KW - United States
KW - Young Adult
U2 - 10.1017/S003329171700277X
DO - 10.1017/S003329171700277X
M3 - SCORING: Journal article
C2 - 28956520
VL - 48
SP - 1299
EP - 1307
JO - PSYCHOL MED
JF - PSYCHOL MED
SN - 0033-2917
IS - 8
ER -