A comparison of the three year course between chronic depression and depression with multiple vs. few prior episodes
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A comparison of the three year course between chronic depression and depression with multiple vs. few prior episodes. / Humer, Elke; Kocsis-Bogar, Krisztina; Berger, Thomas; Schröder, Johanna; Späth, Christina; Meyer, Björn; Moritz, Steffen; Lutz, Wolfgang; Probst, Thomas; Klein, Jan Philipp.
In: PSYCHIAT RES, Vol. 291, 09.2020, p. 113235.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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T1 - A comparison of the three year course between chronic depression and depression with multiple vs. few prior episodes
AU - Humer, Elke
AU - Kocsis-Bogar, Krisztina
AU - Berger, Thomas
AU - Schröder, Johanna
AU - Späth, Christina
AU - Meyer, Björn
AU - Moritz, Steffen
AU - Lutz, Wolfgang
AU - Probst, Thomas
AU - Klein, Jan Philipp
N1 - Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.
PY - 2020/9
Y1 - 2020/9
N2 - This study tested the hypothesis that chronic depression (CD) is more similar to depression with multiple prior episodes (ME) than to depression with few prior episodes (FE). Data from participants (n = 1013) with mild to moderate depressive symptoms (Patient Health Questionnaire [PHQ-9] score 5 - 14) who took part in a randomized control trial of an internet intervention for depression (EVIDENT trial) were re-analyzed. The MINI-interview was conducted to diagnose CD (n = 376). If CD was not diagnosed, the self-reported number of depressive episodes was used to categorize participants as having episodic depression with up to five (FE, n = 422) or more than five (ME, n = 215) prior episodes. Over a three-year period, participants were assessed repeatedly regarding the course of depression (PHQ-9, QIDS), quality of life (SF-12) and therapeutic progress (FEP-2). At baseline, most scores were different between CD and FE but comparable between CD and ME. Time to remission did not differ between CD and ME but was longer in CD compared to FE. Results suggest that ME closely resembles CD and that CD differs from FE.
AB - This study tested the hypothesis that chronic depression (CD) is more similar to depression with multiple prior episodes (ME) than to depression with few prior episodes (FE). Data from participants (n = 1013) with mild to moderate depressive symptoms (Patient Health Questionnaire [PHQ-9] score 5 - 14) who took part in a randomized control trial of an internet intervention for depression (EVIDENT trial) were re-analyzed. The MINI-interview was conducted to diagnose CD (n = 376). If CD was not diagnosed, the self-reported number of depressive episodes was used to categorize participants as having episodic depression with up to five (FE, n = 422) or more than five (ME, n = 215) prior episodes. Over a three-year period, participants were assessed repeatedly regarding the course of depression (PHQ-9, QIDS), quality of life (SF-12) and therapeutic progress (FEP-2). At baseline, most scores were different between CD and FE but comparable between CD and ME. Time to remission did not differ between CD and ME but was longer in CD compared to FE. Results suggest that ME closely resembles CD and that CD differs from FE.
U2 - 10.1016/j.psychres.2020.113235
DO - 10.1016/j.psychres.2020.113235
M3 - SCORING: Journal article
C2 - 32599445
VL - 291
SP - 113235
JO - PSYCHIAT RES
JF - PSYCHIAT RES
SN - 0165-1781
ER -
