A comparative study demonstrated that prevalence figures on multimorbidity require cautious interpretation when drawn from a single database
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A comparative study demonstrated that prevalence figures on multimorbidity require cautious interpretation when drawn from a single database. / Bussche van den, Hendrik; Schäfer, Ingmar; Wiese, Birgitt; Dahlhaus, Anne; Fuchs, Angela; Gensichen, Jochen; Höfels, Susanne; Hansen, Heike; Leicht, Hanna; Koller, Daniela; Luppa, Melanie; Nützel, Anna; Werle, Jochen; Scherer, Martin; Wegscheider, Karl; Glaeske, Gerd; Schön, Gerhard.
In: J CLIN EPIDEMIOL, Vol. 66, No. 2, 2, 2013, p. 209-217.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - A comparative study demonstrated that prevalence figures on multimorbidity require cautious interpretation when drawn from a single database
AU - Bussche van den, Hendrik
AU - Schäfer, Ingmar
AU - Wiese, Birgitt
AU - Dahlhaus, Anne
AU - Fuchs, Angela
AU - Gensichen, Jochen
AU - Höfels, Susanne
AU - Hansen, Heike
AU - Leicht, Hanna
AU - Koller, Daniela
AU - Luppa, Melanie
AU - Nützel, Anna
AU - Werle, Jochen
AU - Scherer, Martin
AU - Wegscheider, Karl
AU - Glaeske, Gerd
AU - Schön, Gerhard
N1 - Copyright © 2013 Elsevier Inc. All rights reserved.
PY - 2013
Y1 - 2013
N2 - OBJECTIVE: We investigated the degree of comparability of the prevalence of chronic diseases and disease combinations in the elderly in two databases comparable with regard to diseases included, sex and age of the patients (65-85 years), and cutoff score for case definition.STUDY DESIGN AND SETTING: One study is based on chart-supported interviews with the primary care physicians within a cohort study of 3,189 multimorbid elderly patients. The second study analyzed claims data from ambulatory care delivered to the multimorbid members of one German Health Insurance (n = 70,031). Multimorbidity was defined by the presence of three or more chronic conditions from an identical list of 46 diseases.RESULTS: The difference of the median number of chronic conditions was 1 (mean 6.7 vs. 5.7). The prevalences of individual conditions were approximately one-third lower in the claims data, but the relative rank order corresponded well between the two databases. These relatively small prevalence differences cumulate when combinations of chronic conditions are investigated, for example, the prevalence differences between the two databases increased to nearly 100% for triadic combinations and nearly 170% for quartets.CONCLUSION: The study shows that conclusions regarding the prevalence of combinations of diseases should be drawn with caution when based on a single database.
AB - OBJECTIVE: We investigated the degree of comparability of the prevalence of chronic diseases and disease combinations in the elderly in two databases comparable with regard to diseases included, sex and age of the patients (65-85 years), and cutoff score for case definition.STUDY DESIGN AND SETTING: One study is based on chart-supported interviews with the primary care physicians within a cohort study of 3,189 multimorbid elderly patients. The second study analyzed claims data from ambulatory care delivered to the multimorbid members of one German Health Insurance (n = 70,031). Multimorbidity was defined by the presence of three or more chronic conditions from an identical list of 46 diseases.RESULTS: The difference of the median number of chronic conditions was 1 (mean 6.7 vs. 5.7). The prevalences of individual conditions were approximately one-third lower in the claims data, but the relative rank order corresponded well between the two databases. These relatively small prevalence differences cumulate when combinations of chronic conditions are investigated, for example, the prevalence differences between the two databases increased to nearly 100% for triadic combinations and nearly 170% for quartets.CONCLUSION: The study shows that conclusions regarding the prevalence of combinations of diseases should be drawn with caution when based on a single database.
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Aged, 80 and over
KW - Sensitivity and Specificity
KW - Risk Assessment
KW - Prevalence
KW - Germany/epidemiology
KW - Databases, Factual
KW - Ambulatory Care/statistics & numerical data
KW - Geriatric Assessment/methods
KW - Chronic Disease/epidemiology
KW - Comorbidity
KW - Data Interpretation, Statistical
KW - Primary Health Care/statistics & numerical data
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Aged, 80 and over
KW - Sensitivity and Specificity
KW - Risk Assessment
KW - Prevalence
KW - Germany/epidemiology
KW - Databases, Factual
KW - Ambulatory Care/statistics & numerical data
KW - Geriatric Assessment/methods
KW - Chronic Disease/epidemiology
KW - Comorbidity
KW - Data Interpretation, Statistical
KW - Primary Health Care/statistics & numerical data
U2 - 10.1016/j.jclinepi.2012.07.019
DO - 10.1016/j.jclinepi.2012.07.019
M3 - SCORING: Journal article
C2 - 23257152
VL - 66
SP - 209
EP - 217
JO - J CLIN EPIDEMIOL
JF - J CLIN EPIDEMIOL
SN - 0895-4356
IS - 2
M1 - 2
ER -