A clinically relevant gene signature in triple negative and basal-like breast cancer.

Achim Rody; Thomas Karn; Cornelia Liedtke; Lajos Pusztai; Eugen Ruckhaeberle; Lars Hanker; Regine Gaetje; Christine Solbach; Andre Ahr; Dirk Metzler; Marcus Schmidt; Volkmar Müller; Uwe Holtrich; Manfred Kaufmann

doi:10.1186/bcr3035

A clinically relevant gene signature in triple negative and basal-like breast cancer.

Achim Rody
Thomas Karn
Cornelia Liedtke
Lajos Pusztai
Eugen Ruckhaeberle
Lars Hanker
Regine Gaetje
Christine Solbach
Andre Ahr
Dirk Metzler
Marcus Schmidt
Volkmar Müller
Uwe Holtrich
Manfred Kaufmann

Related Research units

Department of Gynecology

Abstract

Current prognostic gene expression profiles for breast cancer mainly reflect proliferation status and are most useful in ER-positive cancers. Triple negative breast cancers (TNBC) are clinically heterogeneous and prognostic markers and biology-based therapies are needed to better treat this disease.

Bibliographical data

Original language	English
Article number	5
ISSN	1465-5411
DOIs	https://doi.org/10.1186/bcr3035
Publication status	Published - 2011

pubmed	21978456