Research ExplorerPublicationsA 12-year experience of bipolar steroid-eluting epicardial p...

A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children

Standard

A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children. / Tomaske, Maren; Gerritse, Bart; Kretzers, Leo; Pretre, Rene; Dodge-Khatami, Ali; Rahn, Mariette; Bauersfeld, Urs.

In: ANN THORAC SURG, Vol. 85, No. 5, 05.2008, p. 1704-1711.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Tomaske, M, Gerritse, B, Kretzers, L, Pretre, R, Dodge-Khatami, A, Rahn, M & Bauersfeld, U 2008, 'A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children', ANN THORAC SURG, vol. 85, no. 5, pp. 1704-1711. https://doi.org/10.1016/j.athoracsur.2008.02.016

APA

Tomaske, M., Gerritse, B., Kretzers, L., Pretre, R., Dodge-Khatami, A., Rahn, M., & Bauersfeld, U. (2008). A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children. ANN THORAC SURG, 85(5), 1704-1711. https://doi.org/10.1016/j.athoracsur.2008.02.016

Vancouver

Tomaske M, Gerritse B, Kretzers L, Pretre R, Dodge-Khatami A, Rahn M et al. A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children. ANN THORAC SURG. 2008 May;85(5):1704-1711. https://doi.org/10.1016/j.athoracsur.2008.02.016

Bibtex

@article{1976d5fc7ba048e89af793f1c920a760,
title = "A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children",
abstract = "BACKGROUND: Cardiovascular abnormalities and small vascular size may preclude transvenous pacing and necessitate epicardial lead implantation. This study evaluates the performance of steroid-eluting, bipolar epicardial pacing leads.METHODS: We prospectively enrolled 114 children with 239 atrial and ventricular bipolar epicardial leads (Medtronic CapSure 10366 or 4968, Minneapolis, MN), followed up to 12.2 years (median, 3.2). Lead data were obtained at implant and at semi-annual visits. Analysis was done for left or right atrial and ventricular leads.RESULTS: Median atrial and ventricular pacing thresholds remained below 1.2 V at 0.5 ms. Thresholds did not differ between pacing sites: left atrial, 0.82 V at 0.5 ms; right atrial, 0.74 V at 0.5 ms (p = 0.85); and left ventricular, 0.96 V at 0.5 ms; right ventricular, 0.94 V at 0.5 ms (p = 0.65). Sensing demonstrated no difference for atrial leads, at left atrial, 3.4 mV; and right atrial, 2.9 mV (p = 0.12), but there was superiority of left over right ventricular leads (11.2 vs 7.7 mV, p = 0.002). During follow-up, the 239 atrial and ventricular leads experienced 19 (8%) lead failures. Lead survival at 2 and 5 years was 99% and 94% for atrial leads and 96% and 85% for ventricular leads, respectively.CONCLUSIONS: Bipolar steroid-eluting epicardial leads demonstrate excellent sensing characteristics and persistent low median pacing thresholds below 1.2 V at 0.5 ms in children during up to 12 years follow-up. Considering growing and active patients with most having congenital heart disease, the lead survival of 85% to 94% at 5 years is favorable. Subanalysis shows superior sensing for left ventricular leads. Bipolar steroid-eluting leads provide an alternative approach for permanent pacing and may also be considered for left atrial and ventricular pacing, resynchronization, or defibrillator therapy.",
keywords = "Adolescent, Child, Child, Preschool, Cohort Studies, Defibrillators, Implantable, Dexamethasone/administration & dosage, Electrocardiography, Electrodes, Implanted, Equipment Design, Equipment Failure, Female, Follow-Up Studies, Heart Atria/physiopathology, Heart Defects, Congenital/physiopathology, Heart Ventricles/physiopathology, Humans, Infant, Infant, Newborn, Male, Pacemaker, Artificial, Pericardium/physiopathology, Telemetry",
author = "Maren Tomaske and Bart Gerritse and Leo Kretzers and Rene Pretre and Ali Dodge-Khatami and Mariette Rahn and Urs Bauersfeld",
year = "2008",
month = may,
doi = "10.1016/j.athoracsur.2008.02.016",
language = "English",
volume = "85",
pages = "1704--1711",
journal = "ANN THORAC SURG",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "5",

}

RIS

TY - JOUR

T1 - A 12-year experience of bipolar steroid-eluting epicardial pacing leads in children

AU - Tomaske, Maren

AU - Gerritse, Bart

AU - Kretzers, Leo

AU - Pretre, Rene

AU - Dodge-Khatami, Ali

AU - Rahn, Mariette

AU - Bauersfeld, Urs

PY - 2008/5

Y1 - 2008/5

N2 - BACKGROUND: Cardiovascular abnormalities and small vascular size may preclude transvenous pacing and necessitate epicardial lead implantation. This study evaluates the performance of steroid-eluting, bipolar epicardial pacing leads.METHODS: We prospectively enrolled 114 children with 239 atrial and ventricular bipolar epicardial leads (Medtronic CapSure 10366 or 4968, Minneapolis, MN), followed up to 12.2 years (median, 3.2). Lead data were obtained at implant and at semi-annual visits. Analysis was done for left or right atrial and ventricular leads.RESULTS: Median atrial and ventricular pacing thresholds remained below 1.2 V at 0.5 ms. Thresholds did not differ between pacing sites: left atrial, 0.82 V at 0.5 ms; right atrial, 0.74 V at 0.5 ms (p = 0.85); and left ventricular, 0.96 V at 0.5 ms; right ventricular, 0.94 V at 0.5 ms (p = 0.65). Sensing demonstrated no difference for atrial leads, at left atrial, 3.4 mV; and right atrial, 2.9 mV (p = 0.12), but there was superiority of left over right ventricular leads (11.2 vs 7.7 mV, p = 0.002). During follow-up, the 239 atrial and ventricular leads experienced 19 (8%) lead failures. Lead survival at 2 and 5 years was 99% and 94% for atrial leads and 96% and 85% for ventricular leads, respectively.CONCLUSIONS: Bipolar steroid-eluting epicardial leads demonstrate excellent sensing characteristics and persistent low median pacing thresholds below 1.2 V at 0.5 ms in children during up to 12 years follow-up. Considering growing and active patients with most having congenital heart disease, the lead survival of 85% to 94% at 5 years is favorable. Subanalysis shows superior sensing for left ventricular leads. Bipolar steroid-eluting leads provide an alternative approach for permanent pacing and may also be considered for left atrial and ventricular pacing, resynchronization, or defibrillator therapy.

AB - BACKGROUND: Cardiovascular abnormalities and small vascular size may preclude transvenous pacing and necessitate epicardial lead implantation. This study evaluates the performance of steroid-eluting, bipolar epicardial pacing leads.METHODS: We prospectively enrolled 114 children with 239 atrial and ventricular bipolar epicardial leads (Medtronic CapSure 10366 or 4968, Minneapolis, MN), followed up to 12.2 years (median, 3.2). Lead data were obtained at implant and at semi-annual visits. Analysis was done for left or right atrial and ventricular leads.RESULTS: Median atrial and ventricular pacing thresholds remained below 1.2 V at 0.5 ms. Thresholds did not differ between pacing sites: left atrial, 0.82 V at 0.5 ms; right atrial, 0.74 V at 0.5 ms (p = 0.85); and left ventricular, 0.96 V at 0.5 ms; right ventricular, 0.94 V at 0.5 ms (p = 0.65). Sensing demonstrated no difference for atrial leads, at left atrial, 3.4 mV; and right atrial, 2.9 mV (p = 0.12), but there was superiority of left over right ventricular leads (11.2 vs 7.7 mV, p = 0.002). During follow-up, the 239 atrial and ventricular leads experienced 19 (8%) lead failures. Lead survival at 2 and 5 years was 99% and 94% for atrial leads and 96% and 85% for ventricular leads, respectively.CONCLUSIONS: Bipolar steroid-eluting epicardial leads demonstrate excellent sensing characteristics and persistent low median pacing thresholds below 1.2 V at 0.5 ms in children during up to 12 years follow-up. Considering growing and active patients with most having congenital heart disease, the lead survival of 85% to 94% at 5 years is favorable. Subanalysis shows superior sensing for left ventricular leads. Bipolar steroid-eluting leads provide an alternative approach for permanent pacing and may also be considered for left atrial and ventricular pacing, resynchronization, or defibrillator therapy.

KW - Adolescent

KW - Child

KW - Child, Preschool

KW - Cohort Studies

KW - Defibrillators, Implantable

KW - Dexamethasone/administration & dosage

KW - Electrocardiography

KW - Electrodes, Implanted

KW - Equipment Design

KW - Equipment Failure

KW - Female

KW - Follow-Up Studies

KW - Heart Atria/physiopathology

KW - Heart Defects, Congenital/physiopathology

KW - Heart Ventricles/physiopathology

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Pacemaker, Artificial

KW - Pericardium/physiopathology

KW - Telemetry

U2 - 10.1016/j.athoracsur.2008.02.016

DO - 10.1016/j.athoracsur.2008.02.016

M3 - SCORING: Journal article

C2 - 18442570

VL - 85

SP - 1704

EP - 1711

JO - ANN THORAC SURG

JF - ANN THORAC SURG

SN - 0003-4975

IS - 5

ER -