3D time-resolved vessel-selective angiography based on pseudo-continuous arterial spin labeling
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3D time-resolved vessel-selective angiography based on pseudo-continuous arterial spin labeling. / Lindner, Thomas; Jensen-Kondering, Ulf; van Osch, Matthias J P; Jansen, Olav; Helle, Michael.
In: MAGN RESON IMAGING, Vol. 33, No. 6, 07.2015, p. 840-6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - 3D time-resolved vessel-selective angiography based on pseudo-continuous arterial spin labeling
AU - Lindner, Thomas
AU - Jensen-Kondering, Ulf
AU - van Osch, Matthias J P
AU - Jansen, Olav
AU - Helle, Michael
N1 - Copyright © 2015 Elsevier Inc. All rights reserved.
PY - 2015/7
Y1 - 2015/7
N2 - Angiographic imaging is an important diagnostic tool for the assessment of the intracranial arterial status. Using arterial spin labeling (ASL) techniques, it is possible to visualize the arteries without the administration of exogenous contrast agents. Moreover, modifications of the labeling method allow for the visualization of single arterial trees. In this study, an approach is presented for time-resolved MR angiography based on superselective ASL and keyhole accelerated image acquisition in order to selectively visualize individual cerebral arteries in a clinically acceptable scan time. Keyhole percentage as well as the flip angle of the acquisition sequence was optimized in numerical simulations. Subsequently, the method was validated in healthy volunteers. As a result, image acquisition in 5 minutes with a temporal resolution of 100 ms and spatial resolution below 1 mm was achieved.
AB - Angiographic imaging is an important diagnostic tool for the assessment of the intracranial arterial status. Using arterial spin labeling (ASL) techniques, it is possible to visualize the arteries without the administration of exogenous contrast agents. Moreover, modifications of the labeling method allow for the visualization of single arterial trees. In this study, an approach is presented for time-resolved MR angiography based on superselective ASL and keyhole accelerated image acquisition in order to selectively visualize individual cerebral arteries in a clinically acceptable scan time. Keyhole percentage as well as the flip angle of the acquisition sequence was optimized in numerical simulations. Subsequently, the method was validated in healthy volunteers. As a result, image acquisition in 5 minutes with a temporal resolution of 100 ms and spatial resolution below 1 mm was achieved.
KW - Adult
KW - Cerebral Arteries/anatomy & histology
KW - Female
KW - Humans
KW - Image Interpretation, Computer-Assisted/methods
KW - Imaging, Three-Dimensional/methods
KW - Magnetic Resonance Angiography/methods
KW - Male
KW - Reference Values
KW - Spin Labels
U2 - 10.1016/j.mri.2015.03.001
DO - 10.1016/j.mri.2015.03.001
M3 - SCORING: Journal article
C2 - 25777269
VL - 33
SP - 840
EP - 846
JO - MAGN RESON IMAGING
JF - MAGN RESON IMAGING
SN - 0730-725X
IS - 6
ER -