Research ExplorerPublications15 Jahre histopathologischer Synovialitis-Score

15 Jahre histopathologischer Synovialitis-Score

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15 Jahre histopathologischer Synovialitis-Score : Rückblick und Weiterentwicklung eines diagnostischen Scores. / Krenn, V; Perino, G; Rüther, W; Krenn, V T; Huber, M; Hügle, T; Najm, A; Müller, S; Boettner, F; Pessler, F; Waldstein, W; Kriegsmann, J; Häupl, T; Wienert, S; Krukemeyer, M G; Sesselmann, S; Tikhilov, R; Morawietz, L.

In: Z RHEUMATOL, Vol. 76, No. 6, 08.2017, p. 539-546.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Krenn, V, Perino, G, Rüther, W, Krenn, VT, Huber, M, Hügle, T, Najm, A, Müller, S, Boettner, F, Pessler, F, Waldstein, W, Kriegsmann, J, Häupl, T, Wienert, S, Krukemeyer, MG, Sesselmann, S, Tikhilov, R & Morawietz, L 2017, '15 Jahre histopathologischer Synovialitis-Score: Rückblick und Weiterentwicklung eines diagnostischen Scores', Z RHEUMATOL, vol. 76, no. 6, pp. 539-546. https://doi.org/10.1007/s00393-017-0308-2

APA

Krenn, V., Perino, G., Rüther, W., Krenn, V. T., Huber, M., Hügle, T., Najm, A., Müller, S., Boettner, F., Pessler, F., Waldstein, W., Kriegsmann, J., Häupl, T., Wienert, S., Krukemeyer, M. G., Sesselmann, S., Tikhilov, R., & Morawietz, L. (2017). 15 Jahre histopathologischer Synovialitis-Score: Rückblick und Weiterentwicklung eines diagnostischen Scores. Z RHEUMATOL, 76(6), 539-546. https://doi.org/10.1007/s00393-017-0308-2

Vancouver

Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T et al. 15 Jahre histopathologischer Synovialitis-Score: Rückblick und Weiterentwicklung eines diagnostischen Scores. Z RHEUMATOL. 2017 Aug;76(6):539-546. https://doi.org/10.1007/s00393-017-0308-2

Bibtex

@article{0627a3ff8db24554a5f1b8b07ce7f77f,
title = "15 Jahre histopathologischer Synovialitis-Score: R{\"u}ckblick und Weiterentwicklung eines diagnostischen Scores",
abstract = "The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synovitis, meniscopathy-related synovitis and synovitis in hemochromatosis). Synovitis scores of between ≥ 5 and 9 are classified as high-grade synovitis (rheumatoid arthritis, psoriatic arthritis, Lyme's arthritis, post-infection/reactive arthritis and peripheral arthritis in Bechterew disease); sensitivity is 61.7% and sensitivity 96.1%. According to receiver operating characteristic (ROC) analysis (AUC: 0.8-0.9), diagnostic value is good. National and international acceptance of the synovitis score has grown since the first publication in 2002 and a related follow-up publication in 2006. PubMed data analysis (as of 11.01.2017) yielded the following citation values according to {"}cited by PubMed Central articles{"} for two publications relating to the synovitis score: there were 29 cited-by-PubMed articles for DOI: 10.1078/0344-0338-5710261 , and 44 cited-in-PubMed articles for the second publication, DOI: 10.1111/j.1365-2559.2006.02508 . This makes a total of 73 PubMed citations over a period of 15 years, thereby evidencing the score's international acceptance. Immunohistochemical determination of a number of CD antigens relevant to inflammation has been proposed to further specify the synovitis score for the purposes of risk stratification of high-grade synovitis (e.g., risk of progression and sensitivity to biological agents).",
keywords = "English Abstract, Journal Article, Review",
author = "V Krenn and G Perino and W R{\"u}ther and Krenn, {V T} and M Huber and T H{\"u}gle and A Najm and S M{\"u}ller and F Boettner and F Pessler and W Waldstein and J Kriegsmann and T H{\"a}upl and S Wienert and Krukemeyer, {M G} and S Sesselmann and R Tikhilov and L Morawietz",
year = "2017",
month = aug,
doi = "10.1007/s00393-017-0308-2",
language = "Deutsch",
volume = "76",
pages = "539--546",
journal = "Z RHEUMATOL",
issn = "0340-1855",
publisher = "D. Steinkopff-Verlag",
number = "6",

}

RIS

TY - JOUR

T1 - 15 Jahre histopathologischer Synovialitis-Score

T2 - Rückblick und Weiterentwicklung eines diagnostischen Scores

AU - Krenn, V

AU - Perino, G

AU - Rüther, W

AU - Krenn, V T

AU - Huber, M

AU - Hügle, T

AU - Najm, A

AU - Müller, S

AU - Boettner, F

AU - Pessler, F

AU - Waldstein, W

AU - Kriegsmann, J

AU - Häupl, T

AU - Wienert, S

AU - Krukemeyer, M G

AU - Sesselmann, S

AU - Tikhilov, R

AU - Morawietz, L

PY - 2017/8

Y1 - 2017/8

N2 - The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synovitis, meniscopathy-related synovitis and synovitis in hemochromatosis). Synovitis scores of between ≥ 5 and 9 are classified as high-grade synovitis (rheumatoid arthritis, psoriatic arthritis, Lyme's arthritis, post-infection/reactive arthritis and peripheral arthritis in Bechterew disease); sensitivity is 61.7% and sensitivity 96.1%. According to receiver operating characteristic (ROC) analysis (AUC: 0.8-0.9), diagnostic value is good. National and international acceptance of the synovitis score has grown since the first publication in 2002 and a related follow-up publication in 2006. PubMed data analysis (as of 11.01.2017) yielded the following citation values according to "cited by PubMed Central articles" for two publications relating to the synovitis score: there were 29 cited-by-PubMed articles for DOI: 10.1078/0344-0338-5710261 , and 44 cited-in-PubMed articles for the second publication, DOI: 10.1111/j.1365-2559.2006.02508 . This makes a total of 73 PubMed citations over a period of 15 years, thereby evidencing the score's international acceptance. Immunohistochemical determination of a number of CD antigens relevant to inflammation has been proposed to further specify the synovitis score for the purposes of risk stratification of high-grade synovitis (e.g., risk of progression and sensitivity to biological agents).

AB - The histopathological synovitis score evaluates in a graded approach, as is largely usual for diagnostic histopathological scores, the immunological and inflammatory changes caused by synovitis. A synovitis score of between 1 and ≤ 4 is classified as low-grade (osteoarthritis-related synovitis, post-traumatic synovitis, meniscopathy-related synovitis and synovitis in hemochromatosis). Synovitis scores of between ≥ 5 and 9 are classified as high-grade synovitis (rheumatoid arthritis, psoriatic arthritis, Lyme's arthritis, post-infection/reactive arthritis and peripheral arthritis in Bechterew disease); sensitivity is 61.7% and sensitivity 96.1%. According to receiver operating characteristic (ROC) analysis (AUC: 0.8-0.9), diagnostic value is good. National and international acceptance of the synovitis score has grown since the first publication in 2002 and a related follow-up publication in 2006. PubMed data analysis (as of 11.01.2017) yielded the following citation values according to "cited by PubMed Central articles" for two publications relating to the synovitis score: there were 29 cited-by-PubMed articles for DOI: 10.1078/0344-0338-5710261 , and 44 cited-in-PubMed articles for the second publication, DOI: 10.1111/j.1365-2559.2006.02508 . This makes a total of 73 PubMed citations over a period of 15 years, thereby evidencing the score's international acceptance. Immunohistochemical determination of a number of CD antigens relevant to inflammation has been proposed to further specify the synovitis score for the purposes of risk stratification of high-grade synovitis (e.g., risk of progression and sensitivity to biological agents).

KW - English Abstract

KW - Journal Article

KW - Review

U2 - 10.1007/s00393-017-0308-2

DO - 10.1007/s00393-017-0308-2

M3 - SCORING: Review

C2 - 28470440

VL - 76

SP - 539

EP - 546

JO - Z RHEUMATOL

JF - Z RHEUMATOL

SN - 0340-1855

IS - 6

ER -