PD Dr. med. ID: 43961
Tim Ullrich Magnus
Publications
- 2002
Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system
Magnus, T., Chan, A., Linker, R. A., Toyka, K. V. & Gold, R., 09.2002, In: J NEUROPATH EXP NEUR. 61, 9, p. 760-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Autoimmune modulation of astrocyte-mediated homeostasis.
Korn, T., Rao, M. & Magnus, T., 2007, In: NEUROMOL MED. 9, 1, p. 1-16 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response.
Cassiani-Ingoni, R., Muraro, P. A., Magnus, T., Reichert-Scrivner, S., Schmidt, J., Huh, J., Quandt, J. A., Bratincsak, A., Shahar, T., Eusebi, F., Sherman, L. S., Mattson, M. P., Martin, R. & Rao, M. S., 2007, In: J NEUROPATH EXP NEUR. 66, 7, p. 637-649 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.
Magnus, T., Coksaygan, T., Korn, T., Xue, H., Arumugam, T. V., Mughal, M. R., Eckley, D. M., Tang, S-C., Detolla, L., Rao, M. S., Cassiani-Ingoni, R. & Mattson, M. P., 2007, In: J NEUROSCI RES. 85, 10, p. 2126-2137 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.
Arumugam, T. V., Tang, S-C., Lathia, J. D., Cheng, A., Mughal, M. R., Chigurupati, S., Magnus, T., Chan, S. L., Jo, D-G., Ouyang, X., Fairlie, D. P., Granger, D. N., Vortmeyer, A., Basta, M. & Mattson, M. P., 2007, In: P NATL ACAD SCI USA. 104, 35, p. 14104-14109 35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
Tang, S-C., Arumugam, T. V., Cutler, R. G., Jo, D-G., Magnus, T., Chan, S. L., Mughal, M. R., Telljohann, R. S., Nassar, M., Ouyang, X., Calderan, A., Ruzza, P., Guiotto, A. & Mattson, M. P., 2007, In: J NEUROCHEM. 101, 3, p. 729-736 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.
Lathia, J. D., Patton, B., Eckley, D. M., Magnus, T., Mughal, M. R., Sasaki, T., Caldwell, M. A., Rao, M. S., Mattson, M. P. & Ffrench-Constant, C., 2007, In: J COMP NEUROL. 505, 6, p. 630-643 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits.
Tang, S-C., Arumugam, T. V., Xu, X., Cheng, A., Mughal, M. R., Jo, D. G., Lathia, J. D., Siler, D. A., Chigurupati, S., Ouyang, X., Magnus, T., Camandola, S. & Mattson, M. P., 2007, In: P NATL ACAD SCI USA. 104, 34, p. 13798-13803 34.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS.
Carmen, J., Magnus, T., Cassiani-Ingoni, R., Sherman, L., Rao, M. S. & Mattson, M. P., 2007, In: PROG NEUROBIOL. 82, 3, p. 151-162 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Adult glial precursor proliferation in mutant SOD1G93A mice.
Magnus, T., Carmen, J., Deleon, J., Xue, H., Pardo, A. C., Lepore, A. C., Mattson, M. P., Rao, M. S. & Maragakis, N. J., 2008, In: GLIA. 56, 2, p. 200-208 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell myths.
Magnus, T., Liu, Y., Parker, G. C. & Rao, M. S., 2008, In: PHILOS T R SOC B. 363, 1489, p. 9-22 1489.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting TNF-alpha receptors for neurotherapeutics.
Chadwick, W., Magnus, T., Martin, B., Keselman, A., Mattson, M. P. & Maudsley, S., 2008, In: TRENDS NEUROSCI. 31, 10, p. 504-511 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
Lathia, J. D., Okun, E., Tang, S-C., Griffioen, K., Cheng, A., Mughal, M. R., Laryea, G., Selvaraj, P. K., Ffrench-Constant, C., Magnus, T., Arumugam, T. V. & Mattson, M. P., 2008, In: J NEUROSCI. 28, 51, p. 13978-13984 51.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
HNO exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Choe, C-U., Lewerenz, J., Fischer, G., Uliasz, T. F., Espey, M. G., Hummel, F., Bruce King, S., Schwedhelm, E., Böger, R., Gerloff, C., Hewett, S. J., Magnus, T. & Donzelli, S., 2009, In: J NEUROCHEM.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.
Gelderblom, M., Leypoldt, F., Steinbach, K., Behrens, D., Choe, C-U., Siler, D. A., Arumugam, T. V., Orthey, E., Gerloff, C., Tolosa, E. & Magnus, T., 2009, In: STROKE. 40, 5, p. 1849-1857 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity
Choe, C., Lewerenz, J., Fischer, G., Uliasz, T. F., Espey, M. G., Hummel, F. C., King, S. B., Schwedhelm, E., Böger, R. H., Gerloff, C., Hewett, S. J., Magnus, T. & Donzelli, S., 01.09.2009, In: J NEUROCHEM. 110, 6, p. 1766-73 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Report on the 1st scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Mittenwalde/Motzen, Germany, Oct. 30th - Nov. 1st, 2009.
Magnus, T., Linker, R., Meuth, S. G., Kleinschnitz, C. & Korn, T., 2010, In: Exp Transl Stroke Med. 2, p. 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
[Autoimmune synaptic encephalopathies].
Friese, M. A. & Magnus, T., 2011, In: NERVENARZT. 82, 10, p. 1239-1249 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calorie restriction and stroke.
Manzanero, S., Gelderblom, M., Magnus, T. & Arumugam, T. V., 2011, In: Exp Transl Stroke Med. 3, p. 8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.
Choe, C-U., Lardong, K., Gelderblom, M., Ludewig, P., Leypoldt, F., Koch Nolte, F., Gerloff, C. & Magnus, T., 2011, In: PLOS ONE. 6, 5, p. 19046 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Arumugam, T. V., Cheng, Y-L., Choi, Y., Choi, Y-H., Yang, S., Yun, Y-K., Park, J-S., Yang, D. K., Thundyil, J., Gelderblom, M., Karamyan, V. T., Tang, S-C., Chan, S. L., Magnus, T., Sobey, C. G. & Jo, D-G., 2011, In: MOL PHARMACOL. 80, 1, p. 23-31 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nitroxyl in the central nervous system.
Choe, C-U., Lewerenz, J., Gerloff, C., Magnus, T. & Donzelli, S., 2011, In: ANTIOXID REDOX SIGN. 14, 9, p. 1699-1711 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 2nd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010.
Magnus, T., Linker, R. A., Meuth, S. G., Kleinschnitz, C. & Korn, T., 2011, In: Exp Transl Stroke Med. 3, 1, p. 3 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Seventy years of episodic stiffness: an unusual case of neuromyotonia.
Ganos, C., Münchau, A., Bäumer, T., Gerloff, C. & Magnus, T., 2011, In: MOVEMENT DISORD. 26, 7, p. 1360-1361 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model.
Thundyil, J., Pavlovski, D., Hsieh, Y-H., Gelderblom, M., Magnus, T., Fairlie, D. P. & Arumugam, T. V., 2012, In: NEUROMOL MED. 14, 1, p. 30-39 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
Sydow, K., Schmitz, C., von Leitner, E-C., von Leitner, R., Klinke, A., Atzler, D., Krebs, C., Wieboldt, H., Ehmke, H., Schwedhelm, E., Meinertz, T., Blankenberg, S., Böger, R. H., Magnus, T., Baldus, S. & Wenzel, U., 2012, In: PLOS ONE. 7, 10, p. 48150 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner, J. E., Krebs, C., Tittel, A. P., Paust, H-J., Meyer-Schwesinger, C., Bennstein, S. B., Steinmetz, O., Prinz, I., Magnus, T., Korn, T., Stahl, R. A. K., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 9, p. 1486-1495 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune mechanisms of stroke.
Magnus, T., Wiendl, H. & Kleinschnitz, C., 2012, In: CURR OPIN NEUROL. 25, 3, p. 334-340 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.
Widiapradja, A., Vegh, V., Lok, K. Z., Manzanero, S., Thundyil, J., Gelderblom, M., Cheng, Y-L., Pavlovski, D., Tang, S-C., Jo, D-G., Magnus, T., Chan, S. L., Sobey, C. G., Reutens, D., Basta, M., Mattson, M. P. & Arumugam, T. V., 2012, In: J NEUROCHEM. 122, 2, p. 321-332 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 3'rd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.
Kleinschnitz, C., Meuth, S. G., Magnus, T., Korn, T. & Linker, R. A., 2012, In: Exp Transl Stroke Med. 4, 1, p. 2 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 4'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012.
Linker, R. A., Meuth, S. G., Magnus, T., Korn, T. & Kleinschnitz, C., 2012, In: Exp Transl Stroke Med. 4, 1, p. 22 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Gelderblom, M., Leypoldt, F., Lewerenz, J., Birkenmayer, G., Orozco, D., Ludewig, P., Thundyil, J., Arumugam, T. V., Gerloff, C., Tolosa, E., Maher, P. & Magnus, T., 2012, In: J CEREBR BLOOD F MET. 32, 5, p. 835-843 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak.
Magnus, T., Röther, J., Simova, O., Meier-Cillien, M., Repenthin, J., Möller, F., Gbadamosi, J., Panzer, U., Wengenroth, M., Hagel, C., Kluge, S., Stahl, R. A. K., Wegscheider, K., Urban, P., Eckert, B., Glatzel, M., Fiehler, J. & Gerloff, C., 2012, In: BRAIN. 135, Pt 6, p. 1850-1859 Pt 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.
Leypoldt, F., Buchert, R., Kleiter, I., Marienhagen, J., Gelderblom, M., Magnus, T., Dalmau, J., Gerloff, C. & Lewerenz, J., 01.07.2012, In: J NEUROL NEUROSUR PS. 83, 7, p. 681-686 6 p., 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurologische Manifestationen von Vaskulitiden und primäre ZNS-Vaskulitis
Magnus, T., Melms, A., Kötter, I. & Holle, J. U., 01.09.2012, In: Z RHEUMATOL. 71, 7, p. 551-563 13 p., 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Göbel, K., Schuhmann, M. K., Langhauser, F., Helluy, X., Schwarz, T., Bittner, S., Mayer, C. T., Brede, M., Varallyay, C., Pham, M., Bendszus, M., Jakob, P., Magnus, T., Meuth, S. G., Iwakura, Y., Zernecke, A., Sparwasser, T., Nieswandt, B., Stoll, G. & Wiendl, H., 2013, In: BLOOD. 121, 4, p. 679-691 13 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection.
Zoufaly, A., Cramer, J. P., Vettorazzi, E., Sayk, F., Bremer, J. P., Koop, I., de Weerth, A., Schmiedel, S., Jordan, S., Zimmermann-Fraedrich, K., Asselborn, N. H., Nitschke, M., Neumann-Grutzeck, C., Magnus, T., Rüther, C., Fellermann, K., Stahl, R. K., Wegscheider, K. & Lohse, A. W., 2013, In: PLOS ONE. 8, 3, p. e59209 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
Gelderblom, M., Neumann, M., Ludewig, P., Bernreuther, C., Krasemann, S., Arunachalam, P., Gerloff, C., Glatzel, M. & Magnus, T., 01.01.2013, In: PLOS ONE. 8, 5, p. e63118Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
Fann, D. Y-W., Lee, S. Y., Manzanero, S., Tang, S. C., Gelderblom, M., Chunduri, P., Bernreuther, C., Glatzel, M., Cheng, Y. L., Thundyil, J., Widiapradja, A., Lok, K. Z., Foo, S. L., Wang, Y. C., Li, Y. I., Drummond, G. R., Basta, M., Magnus, T., Jo, D. G., Mattson, M. P., Sobey, C. G. & Arumugam, T. V., 01.01.2013, In: CELL DEATH DIS. 4, p. e790Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 5'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013
Linker, R. A., Magnus, T., Korn, T., Kleinschnitz, C., Meuth, S. G. & speakers at the 5’th NEUROWIND e.V. scientific meeting, 01.01.2013, In: Exp Transl Stroke Med. 5, 1, p. 15Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis
Kluger, M. A., Zahner, G., Paust, H-J., Schaper, M., Magnus, T., Panzer, U. & Stahl, R. A. K., 01.05.2013, In: KIDNEY INT. 83, 5, p. 865-77 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome
Braune, S. A., Wichmann, D., Heinz, M. C., Nierhaus, A., Becker, H., Meyer, T. N., Meyer, G. P., Müller-Schulz, M., Fricke, J., de Weerth, A., Höpker, W-W., Fiehler, J., Magnus, T., Gerloff, C., Panzer, U., Stahl, R. A. K., Wegscheider, K. & Kluge, S., 01.07.2013, In: CRIT CARE MED. 41, 7, p. 1702-10 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply: Blood-cerebrospinal fluid barrier dysfunction in patients with neurological symptoms during the 2011 Northern German Escherichia coli serotype O104:H4 outbreak
Magnus, T., Simova, O., Meier-Cillien, M., Röther, J. & Gerloff, C., 01.08.2013, In: BRAIN. 136, Pt 8, p. e242Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Choe, C., Atzler, D., Wild, P. S., Carter, A. M., Böger, R. H., Ojeda Echevarria, F. M., Simova, O., Stockebrand, M., Lackner, K., Nabuurs, C., Marescau, B., Streichert, T., Müller, C., Lüneburg, N., De Deyn, P. P., Benndorf, R. A., Baldus, S., Gerloff, C., Blankenberg, S., Heerschap, A., Grant, P. J., Magnus, T., Zeller, T., Isbrandt, D. & Schwedhelm, E., 24.09.2013, In: CIRCULATION. 128, 13, p. 1451-61 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke
Ludewig, P., Sedlacik, J., Gelderblom, M., Bernreuther, C., Korkusuz, Y., Wagener, C., Gerloff, C., Fiehler, J., Magnus, T. & Horst, A. K., 27.09.2013, In: CIRC RES. 113, 8, p. 1013-22 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report
Leypoldt, F., Titulaer, M. J., Aguilar, E., Walther, J., Bönstrup, M., Havemeister, S., Teegen, B., Lütgehetmann, M., Rosenkranz, M., Magnus, T. & Dalmau, J., 29.10.2013, In: NEUROLOGY. 81, 18, p. 1637-9 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
Gelderblom, M., Daehn, T., Schattling, B., Ludewig, P., Bernreuther, C., Arunachalam, P., Matschke, J., Glatzel, M., Gerloff, C., Friese, M. A. & Magnus, T., 01.11.2013, In: NEUROBIOL DIS. 59, p. 177-82 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice
Langhauser, F., Kraft, P., Göb, E., Leinweber, J., Schuhmann, M. K., Lorenz, K., Gelderblom, M., Bittner, S., Meuth, S. G., Wiendl, H., Magnus, T. & Kleinschnitz, C., 2014, In: STROKE. 45, 6, p. 1799-+Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobodies as modulators of inflammation: potential applications for acute brain injury
Rissiek, B., Nolte, F. & Magnus, T., 2014, In: FRONT CELL NEUROSCI. 8, p. 344Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review