Prof. Dr. ID: 65683
Boris Fehse
Publications
Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation
Panagiota, V., Thol, F., Markus, B., Fehse, B., Alchalby, H., Badbaran, A., Lehmann, U., Koenecke, C., Shahswar, R., Chaturvedi, A., Stadler, M., Eder, M., Göhring, G., Koenigsmann, M., Kloos, A., Trummer, A., Schroeder, T., Kobbe, G., Thiede, C., Platzbecker, U., Schlegelberger, B., Kreipe, H-H., Ganser, A., Kröger, N. & Heuser, M., 01.07.2014, In: LEUKEMIA. 28, 7, p. 1552-5 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purging and haemopoietic progenitor cell selection by CD34+ cell separation
Krüger, W., Gruber, M., Hennings, S., Fehse, N., Fehse, B., Gutensohn, K., Kröger, N. & Zander, A. R., 04.1998, In: BONE MARROW TRANSPL. 21, 7, p. 665-671 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation
Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.
Bacher, U., Badbaran, A., Fehse, B., Zabelina, T., Zander, A. R. & Kröger, N., 2009, In: EXP HEMATOL. 37, 1, p. 135-142 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid and efficient cloning of proviral flanking fragments by kanamycin resistance gene complementation
Fehse, B., Kühlcke, K., Langer, A., Ostertag, W. & Lother, H., 15.01.1999, In: NUCLEIC ACIDS RES. 27, 2, p. 706-7 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA.
Meyer, J., Rhein, M., Schiedlmeier, B., Kustikova, O., Rudolph, C., Kamino, K., Neumann, T., Yang, M., Wahlers, A., Fehse, B., Reuther, G. W., Schlegelberger, B., Ganser, A., Baum, C. & Li, Z., 2007, In: LEUKEMIA. 21, 10, p. 2171-2180 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resistance of mature T cells to oncogene transformation.
Newrzela, S., Cornils, K., Li, Z., Baum, C., Brugman, M. H., Hartmann, M., Meyer, J., Hartmann, S., Hansmann, M-L., Fehse, B. & von Laer, D., 2008, In: BLOOD. 112, 6, p. 2278-2286 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retrovirale Vektoren – Effiziente Gentaxis für unterschiedliche Gentherapien
Morgan, M. A., Galla, M., Fehse, B. & Schambach, A., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 25-49 25 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Retroviral gene therapy in Germany with a view on previous experience and future perspectives
Morgan, M. A., Galla, M., Grez, M., Fehse, B. & Schambach, A., 09.2021, In: GENE THER. 28, 9, p. 494-512 19 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis
Heim, D., Cornils, K., Schulze, K., Fehse, B., Lohse, A. W., Brümmendorf, T. H. & Wege, H., 2015, In: ONCOGENE. 34, 3, p. 385-393Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertion site analysis in dominant haematopoietic clones.
Kustikova, O. S., Modlich, U. & Fehse, B., 2009, In: Methods Mol Biol. 506, p. 373-390Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral integration site analysis in hematopoietic stem cells.
Kustikova, O. S., Baum, C. & Fehse, B., 2008, In: Methods Mol Biol. 430, p. 255-267Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions.
Giordano, F. A., Fehse, B., Hotz-Wagenblatt, A., Jonnakuty, S., Del Val, C., Appelt, J-U., Nagy, K. Z., Kuehlcke, K., Naundorf, S., Zander, A. R., Zeller, W. J., Ho, A. D., Fruehauf, S. & Laufs, S., 2006, In: BONE MARROW TRANSPL. 38, 3, p. 229-235 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Kustikova, O. S., Geiger, H., Li, Z., Brugman, M. H., Chambers, S. M., Shaw, C. A., Pike-Overzet, K., de Ridder, D., Staal, F. J. T., von Keudell, G., Cornils, K., Nattamai, K. J., Modlich, U., Wagemaker, G., Goodell, M. A., Fehse, B. & Baum, C., 2007, In: BLOOD. 109, 5, p. 1897-1907 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse
Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking with lentiviral vectors for multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Benten, D. & Fehse, B., 2012, In: NAT PHYS. 7, 5, p. 839-849 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma
Waizenegger, J. S., Ben-Batalla, I., Weinhold, N., Meissner, T., Wroblewski, M., Janning, M., Riecken, K., Binder, M., Atanackovic, D., Taipaleenmaeki, H., Schewe, D., Sawall, S., Gensch, V., Cubas-Cordova, M., Seckinger, A., Fiedler, W., Hesse, E., Kröger, N., Fehse, B., Hose, D., Klein, B., Raab, M. S., Pantel, K., Bokemeyer, C. & Loges, S., 01.03.2015, In: LEUKEMIA. 29, 3, p. 696-704 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
„Rote Gentechnologie“ – Nachhaltiges Comeback der Gentherapie?!
Fehse, B., 2018, Vierter Gentechnologiebericht : Bilanzierung einer Hochtechnologie. Hucho, F., Diekämper, J., Fangerau, H., Fehse, B., Hampel, J., Köchy, K., Könninger, S., Marx-Stölting, L., Müller-Röber, B., Reich, J., Schickl, H., Taupitz, J., Walter, J., Zenke, M. & Korte, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 210-214 5 p. (Forschungsberichte der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 40).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT.
Alchalby, H., Badbaran, A., Bock, O., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: BONE MARROW TRANSPL. 45, 9, p. 1404-1407 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening of Potential HIV-1 Inhibitors/Replication Blockers Using Secure Lentiviral in Vitro System.
Prokofjeva, M. M., Spirin, P. V., Yanvarev, D. V., Ivanov, A. V., Novikov, M. S., Stepanov, O. A., Gottikh, M. B., Kochetkov, S. N., Fehse, B., Stocking, C. & Prassolov, V. S., 2012, In: ACTA NATURAE. 3, 4, p. 55-65 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectins mediate small cell lung cancer systemic metastasis
Heidemann, F., Schildt, A., Schmid, K., Bruns, O. T., Riecken, K., Jung, C., Ittrich, H., Wicklein, D., Reimer, R., Fehse, B., Heeren, J., Lüers, G., Schumacher, U. & Heine, M., 01.01.2014, In: PLOS ONE. 9, 4, p. e92327Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selective immunoaffinity-based enrichment of CD34+ cells transduced with retroviral vectors containing an intracytoplasmatically truncated version of the human low-affinity nerve growth factor receptor (deltaLNGFR) gene
Fehse, B., Uhde, A., Fehse, N., Eckert, H. G., Clausen, J., Rüger, R., Koch, S., Ostertag, W., Zander, A. R. & Stockschläder, M., 10.10.1997, In: HUM GENE THER. 8, 15, p. 1815-1824 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Self-inactivating retroviral vectors with improved RNA processing
Kraunus, J., Schaumann, D. H. S., Meyer, J., Modlich, U., Fehse, B., Brandenburg, G., von Laer, D., Klump, H., Schambach, A., Bohne, J. & Baum, C., 11.2004, In: GENE THER. 11, 21, p. 1568-78 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitive balance of suppressing and activating effects of mesenchymal stem cells on T-cell proliferation.
Fang, L., Lange, C., Engel, M., Zander, A. R. & Fehse, B., 2006, In: TRANSPLANTATION. 82, 10, p. 1370-1373 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model
Täger, M., Horn, S., Latuske, E., Ehm, P., Schaks, M., Nalaskowski, M., Fehse, B., Fiedler, W., Stocking, C., Wellbrock, J. & Jücker, M., 11.2017, In: GENE THER. 24, 11, p. 749-753 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Side effects of retroviral gene transfer into hematopoietic stem cells
Baum, C., Düllmann, J., Li, Z., Fehse, B., Meyer, J., Williams, D. A. & von Kalle, C., 15.03.2003, In: BLOOD. 101, 6, p. 2099-114 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Similar outcome of calreticulin type I and calreticulin type II mutations following RIC allogeneic haematopoietic stem cell transplantation for myelofibrosis
Christopeit, M., Badbaran, A., Zabelina, T., Zeck, G., Fehse, B., Ayuketang, F. A., Wolschke, C. & Kröger, N-M., 10.2016, In: BONE MARROW TRANSPL. 51, 10, p. 1391-1393 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Simplified generation of high-titer retrovirus producer cells for clinically relevant retroviral vectors by reversible inclusion of a lox-P-flanked marker gene
Loew, R., Selevsek, N., Fehse, B., von Laer, D., Baum, C., Fauser, A. & Kuehlcke, K., 05.2004, In: MOL THER. 9, 5, p. 738-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
von Wenserski, L., Schultheiß, C., Bolz, S., Schliffke, S., Simnica, D., Willscher, E., Gerull, H., Wolters-Eisfeld, G., Riecken, K., Fehse, B., Altfeld, M., Nollau, P. & Binder, M., 04.2021, In: LEUKEMIA. 35, 4, p. 1073-1086 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SOCS3 promotes interleukin-17 expression of human T cells.
Kleinsteuber, K., Heesch, K., Schattling, S., Sander-Juelch, C., Mock, U., Riecken, K., Fehse, B., Fleischer, B. & Jacobsen, M., 2012, In: BLOOD. 120, 22, p. 4374-4382 22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spleen volume and length determined by computed tomography impact outcome after allogeneic stem cell transplantation for myelofibrosis
Luther, M., Henes, F. O., Zabelina, T., Massoud, R., Janson, D., Wolschke, C., Klyuchnikov, E., Gagelmann, N., Fehse, B., Adam, G., Kröger, N. & Ayuk, F., 07.2023, In: BONE MARROW TRANSPL. 58, 7, p. 755-761 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stand wissenschaftlicher und medizinischer Entwicklungen
Fehse, B., Baum, C., Schmidt, M. & Kalle, C., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 41-126 86 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Stem cell clonality and genotoxicity in hematopoietic cells: gene activation side effects should be avoidable
von Kalle, C., Fehse, B., Layh-Schmitt, G., Schmidt, M., Kelly, P. & Baum, C., 10.2004, In: SEMIN HEMATOL. 41, 4, p. 303-18 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Stem cell clonality -- theoretical concepts, experimental techniques, and clinical challenges
Glauche, I., Bystrykh, L., Eaves, C., Roeder, I. & other participants, 01.04.2013, In: BLOOD CELL MOL DIS. 50, 4, p. 232-40 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Suicide gene therapy for the treatment of high-grade glioma: past lessons, present trends, and future prospects
Hossain, J. A., Marchini, A., Fehse, B., Bjerkvig, R. & Miletic, H., 10.07.2020, In: NEURO-ONCOL ADV. 2, 1, p. vdaa013Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Syngenic graft-versus-chronic-myeloid-leukemia-effect?
Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer
Berdien, B., Mock, U., Atanackovic, D. & Fehse, B., 27.03.2014, In: GENE THER. 21, p. 539–548Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)
Hambach, J., Riecken, K., Cichutek, S., Schütze, K., Albrecht, B., Petry, K., Röckendorf, J. L., Baum, N., Kröger, N., Hansen, T., Schuch, G., Haag, F., Adam, G., Fehse, B., Bannas, P. & Koch-Nolte, F., 29.01.2020, In: CELLS-BASEL. 9, 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting species D adenoviruses replication to counteract the epidemic keratoconjunctivitis
Nikitenko, N. A., Speiseder, T., Groitl, P., Spirin, P. V., Prokofjeva, M. M., Lebedev, T. D., Rubtsov, P. M., Lam, E., Riecken, K., Fehse, B., Dobner, T. & Prassolov, V. S., 19.03.2015, In: BIOCHIMIE. 113, p. 10-16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration
Gomez-Nicola, D., Suzzi, S., Vargas-Caballero, M., Fransen, N. L., Al-Malki, H., Cebrian-Silla, A., Garcia-Verdugo, J. M., Riecken, K., Fehse, B. & Perry, V. H., 01.08.2014, In: BRAIN. 137, Pt 8, p. 2312-28 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System
Pallasch, F. B., Freytag, V., Kriegs, M., Gatzemeier, D., Mair, T., Voss, H., Riecken, K., Dawood, M., Fehse, B., Efferth, T., Schlüter, H. & Schumacher, U., 19.06.2024, In: CANCERS. 16, 12, 2278.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro
Horn, S., Meyer, J., Heukeshoven, J., Fehse, B., Schulze, C., Li, S., Frey, J., Poll, S., Stocking, C. & Jücker, M., 01.2001, In: LEUKEMIA. 15, 1, p. 112-20 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Themenbereich somatische Gentherapie: aus dem Labor über klinische Studien zum kommerziellen Einsatz
Fehse, B., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 156-183 28 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Themenbereich somatische Gentherapie: Translationale und klinische Forschung
Fehse, B. & Domasch, S., 2015, Dritter Gentechnologiebericht: Analyse einer Hochtechnologie. Müller-Röber, B., Budisa, N., Diekämper, J., Domasch, S., Fehse, B., Hampel, J., Hucho, F., Hümpel, A., Köchy, K., Marx-Stölting, L., Reich, J., Rheinberger, H-J., Ropers, H-H., Taupitz, J., Walter, J. & Zenke, M. (eds.). 1 ed. Baden Baden: Nomos, p. 211-308 98 p. (Forschungsberichte der Interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 32).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia
Schliffke, S., Buhs, S., Bolz, S., Gerull, H., von Wenserski, L., Riecken, K., Fehse, B., Nollau, P. & Binder, M., 12.04.2018, In: BLOOD. 131, 15, p. 1755-1758 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review