Prof. Dr. ID: 65683
Boris Fehse
Publications
Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector
Cornils, K., Bartholomae, C. C., Thielecke, L., Lange, C., Arens, A., Glauche, I., Mock, U., Riecken, K., Gerdes, S., von Kalle, C., Schmidt, M., Roeder, I. & Fehse, B., 01.01.2013, In: EXP HEMATOL. 41, 1, p. 28-38.e3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients
Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of two doses of antithymocyte globulin in patients undergoing matched unrelated donor allogeneic stem cell transplantation.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Wolschke, C., Fehse, B., Bacher, U., Erttmann, R., Kröger, N. & Zander, A. R., 2008, In: BIOL BLOOD MARROW TR. 14, 8, p. 913-919 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Complement-dependent and complement-independent cytotoxicity of polyclonal antithymocyte globulins in chronic lymphocytic leukemia.
Ayuketang Ayuk, F., Atassi, N., Schuch, G., Mina, S., Fang, L., Bokemeyer, C., Fehse, B., Zander, A. R. & Kröger, N., 2008, In: LEUKEMIA RES. 32, 8, p. 1200-1206 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.
Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China
Büning, H., Griesenbach, U., Fehse, B., Ylä-Herttuala, S., Anagnou, N. P., van Beusechem, V., Raya, A. & Verhoeyen, E., 12.2018, In: HUM GENE THER. 29, 12, p. 1337–1338 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correction: Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application
Schwarze, L. I., Głów, D., Sonntag, T., Uhde, A. & Fehse, B., 02.2023, In: GENE THER. 30, 1-2, p. 187Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Correction: Role of growth arrest-specific gene 6-mer axis in multiple myeloma
Waizenegger, J. S., Ben-Batalla, I., Weinhold, N., Meissner, T., Wroblewski, M., Janning, M., Riecken, K., Binder, M., Atanackovic, D., Taipaleenmaeki, H., Schewe, D., Sawall, S., Gensch, V., Cubas-Cordova, M., Seckinger, A., Atanackovic, D., Hesse, E., Kröger, N., Fehse, B., Hose, D., Klein, B., Raab, M. S., Pantel, K., Bokemeyer, C. & Loges, S., 09.2020, In: LEUKEMIA. 34, 9, p. 2542Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
CRISPR-to-Kill (C2K)–Employing the Bacterial Immune System to Kill Cancer Cells
Glow, D., Maire, C., Schwarze, L-I., Lamszus, K. & Fehse, B., 15.12.2021, In: CANCERS. 13, 24, 6306.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs
Ben-Batalla, I., Cubas-Cordova, M., Udonta, F., Wroblewski, M., Waizenegger, J. S., Janning, M., Sawall, S., Gensch, V., Zhao, L., Martinez-Zubiaurre, I., Riecken, K., Fehse, B., Pantel, K., Bokemeyer, C. & Loges, S., 20.03.2015, In: ONCOTARGET. 6, 8, p. 6341-58 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep Characterization and Comparison of Different Retrovirus-like Particles Preloaded with CRISPR/Cas9 RNPs
Wichmann, M., Maire, C. L., Nuppenau, N., Habiballa, M., Uhde, A., Kolbe, K., Schröder, T., Lamszus, K., Fehse, B. & Głów, D., 13.07.2023, In: INT J MOL SCI. 24, 14, p. 11399Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL
Schieferdecker, A., Voigt, M., Riecken, K., Braig, F., Schinke, T., Loges, S., Bokemeyer, C., Fehse, B. & Binder, M., 30.08.2014, In: ONCOTARGET. 5, 16, p. 6647-53 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of CAR-T cell therapies for multiple myeloma
Gagelmann, N., Riecken, K., Wolschke, C., Berger, C., Ayuk, F. A., Fehse, B. & Kröger, N., 09.2020, In: LEUKEMIA. 34, 9, p. 2317-2332 16 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF.
Siebolts, U., Thiele, J., Zander, T., Ditschkowski, M., Beelen, D. W., Kröger, N., Fehse, B. & Wickenhauser, C., 2008, In: ONCOL REP. 19, 1, p. 287-292 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital-droplet PCR assays for IDH, DNMT3A and driver mutations to monitor after allogeneic stem cell transplantation minimal residual disease of myelofibrosis
Mannina, D., Badbaran, A., Wolschke, C., Klyuchnikov, E., Christopeit, M., Fehse, B. & Kröger, N., 03.2022, In: BONE MARROW TRANSPL. 57, 3, p. 510-512 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Digital-PCR assay for screening and quantitative monitoring of calreticulin (CALR) type-2 positive patients with myelofibrosis following allogeneic stem cell transplantation
Badbaran, A., Fehse, B., Christopeit, M., Aranyossy, T., Ayuketang, F. A., Wolschke, C. & Kröger, N., 06.2016, In: BONE MARROW TRANSPL. 51, 6, p. 872-3Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel
Fehse, B., Badbaran, A., Berger, C., Sonntag, T., Riecken, K., Geffken, M., Kröger, N. & Ayuk, F. A., 13.03.2020, In: MOL THER-METH CLIN D. 16, p. 172-178 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR Panel for Sensitive Hematopoietic Chimerism Quantification after Allogeneic Stem Cell Transplantation
Stahl, T., Rothe, C., Böhme, M. U., Kohl, A., Kröger, N. & Fehse, B., 2016, In: INT J MOL SCI. 17, 9, p. E1515Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases
Mock, U., Hauber, I. & Fehse, B., 03.2016, In: NAT PROTOC. 11, 3, p. 598-615 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to assess hematopoietic chimerism after allogeneic stem cell transplantation
Stahl, T., Böhme, M., Kröger, N. & Fehse, B., 18.03.2015, In: EXP HEMATOL. 43, 6, p. 462-468Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues
Badbaran, A., Mailer, R. K., Dahlke, C., Woens, J., Fathi, A., Mellinghoff, S. C., Renné, T., Addo, M. M., Riecken, K. & Fehse, B., 10.12.2021, In: MOL THER-METH CLIN D. 23, p. 418-423 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diva-Fit: A step-by-step manual for generating high-resolution graphs and histogram overlays of flow cytometry data obtained with FACSDiva software
Riecken, K. & Fehse, B., 2009, In: CTT-Cell Ther Transpl. 1, 4, p. 1-4 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dominant selection of hematopoietic progenitor cells with retroviral MDR1 co-expression vectors
Hildinger, M., Fehse, B., Hegewisch-Becker, S., John, J., Rafferty, J. R., Ostertag, W. & Baum, C., 01.01.1998, In: HUM GENE THER. 9, 1, p. 33-42 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients
Kruchen, A., Stahl, T., Gieseke, F., Binder, T. M. C., Özcan, Z., Meisel, R., Kreyenberg, H., Bader, P., Gruhn, B., Greil, J., Pfeiffer, M., Döring, M., Handgretinger, R., Fehse, B. & Müller, I., 22.06.2015, In: BONE MARROW TRANSPL. 50, 10, p. 1367-1370Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Donor Lymphocyte Infusion and Molecular Monitoring for Relapsed Myelofibrosis After Hematopoietic Cell Transplantation
Gagelmann, N., Wolschke, C., Badbaran, A., Janson, D., Berger, C., Klyuchnikov, E., Ayuk, F., Fehse, B. & Kröger, N., 07.2023, In: HEMASPHERE. 7, 7, p. e921Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population
Kustikova, O. S., Wahlers, A., Kuhlcke, K., Stahle, B., Zander, A. R., Baum, C. & Fehse, B., 01.12.2003, In: BLOOD. 102, 12, p. 3934-7 4 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers
Timin, A. S., Muslimov, A. R., Lepik, K. V., Epifanovskaya, O. S., Shakirova, A. I., Mock, U., Riecken, K., Okilova, M. V., Sergeev, V. S., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 01.2018, In: NANOMED-NANOTECHNOL. 14, 1, p. 97-108 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient lentiviral transduction and transgene expression in primary human B cells.
Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient Pseudotyping of Different Retroviral Vectors Using a Novel, Codon-Optimized Gene for Chimeric GALV Envelope
Mirow, M., Schwarze, L. I., Fehse, B. & Riecken, K., 27.07.2021, In: VIRUSES-BASEL. 13, 8, 1471.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Einleitung: Gentechnologien in Deutschland im Fokus der IAG Gentechnologiebericht
Fehse, B., Marx-Stölting, L., Schickl, H. & Khachatryan, A., 2021, Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. Fehse, B., Hucho, F., Bartfeld, S., Clemens, S., Erb, T., Fangerau, H., Hampel, J., Korte, M., Marx-Stölting, L., Mundlos, S., Osterheider, A., Pichl, A., Reich, J., Schickl, H., Schicktanz, S., Taupitz, J., Walter, J., Winkler, E. & Zenke, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 81-86 6 p. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 44).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Einleitung: Gen- und Zelltherapie – „zwei Seiten zweier Medaillen“
Fehse, B., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 11-21 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Endogenous retrovirus induces leukemia in a xenograft mouse model for primary myelofibrosis
Triviai, I., Ziegler, M., Bergholz, U., Oler, A. J., Stübig, T., Prassolov, V., Fehse, B., Kozak, C. A., Kröger, N-M. & Stocking, C., 10.06.2014, In: P NATL ACAD SCI USA. 111, 23, p. 8595 - 8600Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
Braig, F., März, M., Schieferdecker, A., Schulte, A., Voigt, M., Stein, A., Grob, T., Alawi, M., Indenbirken, D., Kriegs, M., Engel, E., Vanhoefer, U., Grundhoff, A., Loges, S., Riecken, K., Fehse, B., Bokemeyer, C. & Binder, M., 20.05.2015, In: ONCOTARGET. 6, 14, p. 12035-47 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Erratum for "Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors"
Trepel, M., Körbelin, J., Spies, E., Heckmann, M. B., Hunger, A., Fehse, B., Katus, H. A., Kleinschmidt, J. A., Müller, O. J. & Michelfelder, S., 10.2015, In: GENE THER. 22, 10, p. 840-847Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Excellent proliferation and persistence of allogeneic donor-derived 41-BB based CAR-T cells despite immunosuppression with cyclosporine A
Ayuk, F., Fehse, B., Janson, D., Berger, C., Riecken, K. & Kröger, N., 06.2020, In: HAEMATOLOGICA. 105, 6, p. 322-324 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Excision of specific DNA-sequences from integrated retroviral vectors via site-specific recombination
Bergemann, J., Kühlcke, K., Fehse, B., Ratz, I., Ostertag, W. & Lother, H., 11.11.1995, In: NUCLEIC ACIDS RES. 23, 21, p. 4451-6 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fucoidans as potential inhibitors of HIV-1
Prokofjeva, M. M., Imbs, T. I., Shevchenko, N. M., Spirin, P. V., Horn, S., Fehse, B., Zvyagintseva, T. N. & Prassolov, V. S., 01.01.2013, In: MAR DRUGS. 11, 8, p. 3000-14 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene and Cell Therapy in Germany
von Kalle, C., Fehse, B. & Büning, H., 10.2017, In: HUM GENE THER. 28, 10, p. 781Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation
Staffeldt, L., Mattert, G., Riecken, K., Rövenstrunk, G., Volkmar, A., Heumann, A., Moustafa, M., Jücker, M., Fehse, B., Schumacher, U., Lüth, S. & Kah, J., 30.12.2023, In: CELLS-BASEL. 13, 1, 82.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene Therapy "Made in Germany": A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy
Büning, H., Fehse, B., Ivics, Z., Kochanek, S., Koehl, U., Kupatt, C., Mussolino, C., Nettelbeck, D. M., Schambach, A., Uckert, W., Wagner, E. & Cathomen, T., 10.2021, In: HUM GENE THER. 32, 19-20, p. 987-996 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene therapy strategies: can we eradicate HIV?
van Lunzen, J., Fehse, B. & Hauber, J., 2011, In: CURR HIV-AIDS REP. 8, 2, p. 78-84 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina
Jung, G., Sun, J., Petrowitz, B., Riecken, K., Kruszewski, K., Jankowiak, W., Kunst, F., Skevas, C., Richard, G., Fehse, B. & Bartsch, U., 01.12.2013, In: STEM CELL TRANSL MED. 2, 12, p. 1001-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic barcodes facilitate competitive clonal analyses in vivo
Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In: HUM GENE THER. 28, 10, p. 926-937Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic Modifications – Possibilities and Limits of Gene Therapy
Fehse, B., 2011, Human Nature and Self Design. mentis Verlag Paderborn, p. 113-136 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Genetische Manipulation: klinische Anwendung.
Fehse, B. & Cornils, K., 2015, Hämatopoetische Stammzellen: Grundlagen und klinische Einsatzgebiete. Herr, W., Theobald, M., Ehninger, G., Einsele, H. & Meyer, R. G. (eds.). 1 ed. Köln: Deutscher Ärzte-Verlag, p. 21-24 4 p. 6Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations.
Metzner, A., Horstmann, M., Fehse, B., Ortmeyer, G., Niemeyer, C. M., Stocking, C., Mayr, G. W. & Jücker, M., 2007, In: GENE THER. 14, 8, p. 699-703 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomeditierung durch CRISPR und Co
Fehse, B., 2018, Stammzellforschung: Aktuelle wissenschaftliche und gesellschaftliche Entwicklungen. Zenke, M., Marx-Stölting, L. & Schickl, H. (eds.). 1 ed. Baden-Baden: Nomos, p. 97-114 18 p. 4. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 39).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer
Genome-Editing – Gentherapie 2.0 oder nur eine Wunschvorstellung?
Fehse, B., Grünewald, J. & Petri, K., 30.12.2023, Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft: AG Gentechnologiebericht mit freundlicher Unterstützung der DG-GT und des GSCN. Fehse, B., Schickl, H., Bartfeld, S. & Zenke, M. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 103-120 18 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer